| Record 1 of 44 |
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Title:
Guarding Against China’s Predatory Acquisition of Foreign Technologies: A Quad Perspective
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Author(s):
Tyagi, G (Tyagi, Gaurav); Behera, LK (Behera, Laxman Kumar); Yadav, A (Yadav, Ankur); Verma, NK (Verma, Naresh Kumar) |
| Source:
SCIENCE TECHNOLOGY AND SOCIETY DOI:
10.1177/09717218241238605 Early Access Date:
JUN 2024 Published Date:
2024 JUN 3 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
62
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|
Abstract:
The study examines the response of the Quad countries (Australia, India, Japan and the United States) to People’s Republic of China (PRC)’s predatory acquisition of foreign technologies. This article looks at PRC’s science and technology (S&T) policy and its relation to the grand strategy of attaining global superpower status. The meteoric rise of the PRC in the last four decades has amazed many. Innovation and technological advancement and their alignment with government policies are important factors in this rise. The study notes that PRC’s S&T policy involves, among others, acquiring foreign technologies through illicit means that include stealing through espionage and sophisticated cyberattacks and forcing overseas companies operating in China to share intellectual property rights with local partners. Alarmed by PRC’s predatory strategy, the Quad countries have taken steps to regulate, and in some cases prohibit, the PRC’s targeted foreign investments and coercive and opportunistic takeovers. The article argues that the Quad countries need to coordinate their efforts to effectively counter PRC’s illicit acquisition of their technologies. |
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Accession Number:
WOS:001238159700001
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
China; technology; illicit acquisition; QUAD |
|
Addresses:
[Tyagi, Gaurav; Behera, Laxman Kumar; Yadav, Ankur; Verma, Naresh Kumar] Jawaharlal Nehru Univ, Special Ctr Natl Secur Studies, New Delhi 121003, India. |
|
Corresponding Address:
Tyagi, G (corresponding author), Jawaharlal Nehru Univ, Special Ctr Natl Secur Studies, New Delhi 121003, India. |
|
E-mail Addresses:
gauravtyagi@mail.jnu.ac.in |
|
Affiliations:
Jawaharlal Nehru University, New Delhi |
|
Publisher:
SAGE PUBLICATIONS INDIA PVT LTD
|
|
Publisher Address:
B-1-I-1 MOHAN CO-OPERATIVE INDUSTRIAL AREA, MATHURA RD, POST BAG NO 7, NEW DELHI 110 044, INDIA
|
|
Web of Science Index:
Social Science Citation Index (SSCI)
|
|
Web of Science Categories:
Management |
|
Research Areas:
Business & Economics |
|
IDS Number:
SZ0R4
|
|
ISSN:
0971-7218
|
|
eISSN:
0973-0796
|
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29-char Source Abbrev.:
SCI TECHNOL SOC
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ISO Source Abbrev.:
Sci. Technol. Soc.
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Source Item Page Count:
19
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| Funding: |
| Funding Agency | Grant Number |
|
CRDF Global Grant |
202108-68023
|
|
|
This work was supported by the CRDF Global Grant (Grant Number: 202108-68023).
|
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Output Date:
2024-07-01
|
| Record 2 of 44 |
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Title:
Energy-efficient communication-aware VM placement in cloud datacenter using hybrid ACO-GWO
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Author(s):
Keshri, R (Keshri, Rashmi); Vidyarthi, DP (Vidyarthi, Deo Prakash) |
| Source:
CLUSTER COMPUTING-THE JOURNAL OF NETWORKS SOFTWARE TOOLS AND APPLICATIONS DOI:
10.1007/s10586-024-04623-z Early Access Date:
JUN 2024 Published Date:
2024 JUN 22 |
|
Times Cited in Web of Science Core Collection:
0
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Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
48
|
|
Abstract:
Virtual machine placement (VMP) is the process of mapping virtual machines to physical machines, which is very important for resource utilization in cloud data centres. As such, VM placement is an NP-class problem, and therefore, researchers have frequently applied meta-heuristics for this. In this study, we applied a hybrid meta-heuristic that combines ant colony optimisation (ACO) and grey wolf optimisation (GWO) to minimise resource wastage, energy consumption, and bandwidth usage. The performance study of the proposed work is conducted on variable number of virtual machines with different resource correlation coefficients. According to the observations, there is 2.85%, 7.61%, 15.78% and 19.41% improvement in power consumption, 26.44%, 57.83%, 77.90% and 83.89% improvement in resource wastage and 2.94%, 8.20%, 9.99% and 10.72% improvement in bandwidth utilisation as compared to multi-objective GA, ACO, FFD and random based algorithm respectively. To study the convergence of the proposed method, it is compared with few recent hybrid meta-heuristic algorithms, namely ACO-PSO, GA-PSO, GA-ACO and GA-GWO which exhibits that the proposed hybrid method converges faster. |
|
Accession Number:
WOS:001251875700004
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
Virtual machine placement (VMP); Ant colony optimization (ACO); Grey wolf optimisation (GWO); Multi-objective optimization; Cloud datacentre; Energy efficiency |
|
KeyWords Plus:
CONSOLIDATION |
|
Addresses:
[Keshri, Rashmi; Vidyarthi, Deo Prakash] Jawaharlal Nehru Univ, Sch Comp Syst Sci, New Delhi 110067, India. |
|
Corresponding Address:
Vidyarthi, DP (corresponding author), Jawaharlal Nehru Univ, Sch Comp Syst Sci, New Delhi 110067, India. |
|
E-mail Addresses:
rashmi59_scs@jnu.ac.in; dpv@mail.jnu.ac.in |
|
Affiliations:
Jawaharlal Nehru University, New Delhi |
|
Publisher:
SPRINGER
|
|
Publisher Address:
ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Computer Science, Information Systems; Computer Science, Theory & Methods |
|
Research Areas:
Computer Science |
|
IDS Number:
UZ4O4
|
|
ISSN:
1386-7857
|
|
eISSN:
1573-7543
|
|
29-char Source Abbrev.:
CLUSTER COMPUT
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|
ISO Source Abbrev.:
Cluster Comput.
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|
Source Item Page Count:
28
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|
Output Date:
2024-07-01
|
| Record 3 of 44 |
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Title:
Small Town Stardom and theBig Picture: Cinematic Intimacies on TikTok Ishani Dey
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Author(s):
Dey, I (Dey, Ishani) |
| Source:
BIOSCOPE-SOUTH ASIAN SCREEN STUDIES DOI:
10.1177/09749276241252631 Early Access Date:
JUN 2024 Published Date:
2024 JUN 9 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
53
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|
Abstract:
This article demonstrates how new media technologies remediate traditional cinematic modes of stardom, specifically in and through small towns in India. Through two case studies, it explores registers of stardom that have emerged through the short video sharing app TikTok – both on the platform and in its filmic renditions. The first case looks at the cinematic construct of a TikTok star, which fuels the formal and narrative force of the 2019 film Bala (dir. Amar Kaushik). Bala illustrates how cinema can self-reflexively interweave traditional tropes with new media technologies. The second case features a ‘real-life’ TikTok star and political aspirant who brings into focus the political and electoral valence of TikTok stardom in the town of Adampur, Haryana. The cinematic is central to this narrative, where cinephilic nostalgia indicates a shared cultural intimacy between the political candidate and her followers and helps further her political ambitions. While the real TikTok star, Sonali Phogat, directly addresses her constituency, lip-syncing to old movie songs in 15-second videos, her reel counterparts pay homage to their cine-ancestors, 15 seconds at a time. In a setting where ‘the star’ has traditionally been understood through the prism of cinema, this article brings to light shifting registers invoked through the platformisation of the star and the cinematic in small town India. |
|
Accession Number:
WOS:001241122000001
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
TikTok; Bala; remediation; stardom; cinephilia; OTT; platforms |
|
KeyWords Plus:
FILM |
|
Addresses:
[Dey, Ishani] Jawaharlal Nehru Univ, Sch Arts & Aesthet, Dept Cinema Studies, New Delhi, India. |
|
Corresponding Address:
Dey, I (corresponding author), Jawaharlal Nehru Univ, Sch Arts & Aesthet, Dept Cinema Studies, New Delhi, India. |
|
E-mail Addresses:
ishani.dey@gmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi |
|
Publisher:
SAGE PUBLICATIONS INDIA PVT LTD
|
|
Publisher Address:
B-1-I-1 MOHAN CO-OPERATIVE INDUSTRIAL AREA, MATHURA RD, POST BAG NO 7, NEW DELHI 110 044, INDIA
|
|
Web of Science Index:
Arts & Humanities Citation Index (A&HCI)
|
|
Web of Science Categories:
Film, Radio, Television; Asian Studies |
|
Research Areas:
Film, Radio & Television; Asian Studies |
|
IDS Number:
TK3R1
|
|
ISSN:
0974-9276
|
|
eISSN:
0976-352X
|
|
29-char Source Abbrev.:
BIOSCOPE
|
|
ISO Source Abbrev.:
BioScope S. Asian Screen Stud.
|
|
Source Item Page Count:
20
|
| Funding: |
| Funding Agency | Grant Number |
|
Jawaharlal Nehru University | |
|
|
The author extends her sincere gratitude to Dr Debashree Mukherjee for her meticulous attention to this article, and to the anonymous peer reviewer for their encouraging feedback. The author acknowledges with appreciation the guidance provided by Professor Ravi Vasudevan and Professor Ravi Sundaram in the early stages. An initial draft of this article was presented at a conference organised by the Department of Cinema Studies at the School of Arts and Aesthetics, Jawaharlal Nehru University. The author is grateful for the feedback received from the faculty and cohort. Special thanks to Dr Vebhuti Duggal for her unwavering support throughout this process and to Sarah Khan for her technical assistance.
|
|
Output Date:
2024-07-01
|
| Record 4 of 44 |
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Title:
Mitigation of Carbonaceous Indoor Aerosols Through Behavioural Change Soft Approach in Cooking at Selected Rural Sites (India)
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Author(s):
Verma, K (Verma, Kopal); Kulshrestha, UC (Kulshrestha, Umesh Chandra) |
| Source:
AEROSOL AND AIR QUALITY RESEARCH Volume:
24 Issue:
6 Article Number:
240013 DOI:
10.4209/aaqr.240013 Published Date:
2024 JUN |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
38
|
|
Abstract:
Indoor air pollution particularly from biomass burning, presents a significant challenge in rural India. Despite awareness of cleaner energy sources, rural communities encounter financial and logistical barriers hindering their transition to cleaner energy. The combustion of biomass emits substantial amounts of carbonaceous aerosols (CA), including organic carbon (OC) and elemental carbon (EC), which severely impact health and contribute to climate change. This study is aimed at applying certain behavioural changes in cooking practices, termed here as ‘Soft Approaches,’ to mitigate indoor air pollution. Soft approaches involve minor adjustments in daily practices to promote sustainability. Conducted over a year at three sites in Punjab (Phullanwal) and Madhya Pradesh (Budhwada and Khedla), the study assessed CA concentrations in rural household kitchens. Outdoor CA concentrations were also measured in order to examine the indoor and outdoor differences in CA levels. Mostly, OC and EC concentrations peaked during the winter season, with outdoor levels consistently lower than indoor ones. The implementation of soft approaches such as using table fans for smoke dispersion, employing dried biomass, enhancing ventilation, utilizing biomass in pellet form resulted in reductions of up to 87.1% and 83.6% in indoor OC and EC concentrations, respectively. Questionnaire analysis indicated that the community recognized the benefits of cleaner fuels and soft approaches, despite challenges related to availability and economic feasibility. The adoption of soft approaches offers broader benefits by enhancing adaptive capabilities, fostering resilience to environmental challenges for individuals and the nation as a whole. |
|
Accession Number:
WOS:001249292600007
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Research; Carbonaceous aerosol; Biomass burning; Soft approaches |
|
KeyWords Plus:
RENEWABLE ENERGY; ELEMENTAL CARBON; AIR-POLLUTION; BIOMASS; BARRIERS; IMPACT; REGION |
|
Addresses:
[Verma, Kopal; Kulshrestha, Umesh Chandra] Jawaharlal Nehru Univ, Sch Environm Sci, New Delhi 110067, India. |
|
Corresponding Address:
Kulshrestha, UC (corresponding author), Jawaharlal Nehru Univ, Sch Environm Sci, New Delhi 110067, India. |
|
E-mail Addresses:
umeshkulshrestha@gmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi |
|
Publisher:
TAIWAN ASSOC AEROSOL RES-TAAR
|
|
Publisher Address:
CHAOYANG UNIV TECH, DEPT ENV ENG & MGMT, PROD CTR AAQR, NO 168, JIFONG E RD, WUFONG TOWNSHIP, TAICHUNG COUNTY, 41349, TAIWAN
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Environmental Sciences |
|
Research Areas:
Environmental Sciences & Ecology |
|
IDS Number:
UP6D9
|
|
ISSN:
1680-8584
|
|
eISSN:
2071-1409
|
|
29-char Source Abbrev.:
AEROSOL AIR QUAL RES
|
|
ISO Source Abbrev.:
Aerosol Air Qual. Res.
|
|
Source Item Page Count:
16
|
| Funding: |
| Funding Agency | Grant Number |
|
CSIR-UGC JRF | |
|
DST -PURSE | |
|
CIF Facility in School of Environmental Sciences, Jawaharlal Nehru University, New Delhi | |
|
|
We sincerely thank the financial support received from CSIR-UGC JRF, DST -PURSE, and CIF Facility in School of Environmental Sciences, Jawaharlal Nehru University, New Delhi and gratefully acknowledge the support of the residents of sampling houses, to conduct this research work. This study is a part of DRS -Net (Deposition Research Network through students) -India of Prof U.C. Kulshrestha.
|
|
Open Access:
gold
|
|
Output Date:
2024-07-01
|
| Record 5 of 44 |
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Title:
<i>Shaheed-e-Azam Bhagat Singh</i> (1954): A Curious Case of the First Biopic on the Indian Revolutionary Martyr
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Author(s):
Singh, R (Singh, Ravinder) |
| Source:
BIOSCOPE-SOUTH ASIAN SCREEN STUDIES DOI:
10.1177/09749276241252938 Early Access Date:
JUN 2024 Published Date:
2024 JUN 9 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
61
|
|
Abstract:
Immediately after India’s independence, the Indian revolutionary martyr Bhagat Singh became the focus of several competing biopic projects. A censorship controversy erupted around the making of the now-lost film filmindia (1954), the first biopic on the martyr. It became a contentious site where the interests of the filmmakers, former revolutionary colleagues of Bhagat Singh and his family members, and various other stakeholders like public representatives, intersected with an almost disinterested state. Following Debashree Mukherjee’s (2019) methodological approach of considering film censorship ‘as a productive material site for the study of lost films’, this article enters into a microhistory of this controversy by utilising bureaucratic paperwork and filmic and nonfilmic paratextual material to compensate for the absent film element. By tracing the very first attempts which were made to mount a biopic on Bhagat Singh, I try to investigate personal and political motivations behind the race to make the first biopic on the revolutionary martyr. For this purpose, I employ Chris Moffat’s (2019) mobilisation of the metaphors of corpse, corpus and corps, which he productively uses to understand the politics behind the multifarious afterlives of Bhagat Singh and wrangle over his revolutionary inheritance in the post-colonial period, and make a case for the importance of the study of Bhagat Singh’s hitherto neglected biopics by arguing that the time of their making, their production contexts and attendant controversies afford us unique insights into what Moffat terms the politics of ‘India’s revolutionary inheritance’. |
|
Accession Number:
WOS:001242224900001
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
Shaheed-e-Azam Bhagat Singh; revolutionary martyr; biopic; censorship |
|
Addresses:
[Singh, Ravinder] Jawaharlal Nehru Univ, Sch Arts & Aesthet, New Delhi, India. |
|
Corresponding Address:
Singh, R (corresponding author), Jawaharlal Nehru Univ, Sch Arts & Aesthet, New Delhi, India. |
|
E-mail Addresses:
ravindersonkla@gmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi |
|
Publisher:
SAGE PUBLICATIONS INDIA PVT LTD
|
|
Publisher Address:
B-1-I-1 MOHAN CO-OPERATIVE INDUSTRIAL AREA, MATHURA RD, POST BAG NO 7, NEW DELHI 110 044, INDIA
|
|
Web of Science Index:
Arts & Humanities Citation Index (A&HCI)
|
|
Web of Science Categories:
Film, Radio, Television; Asian Studies |
|
Research Areas:
Film, Radio & Television; Asian Studies |
|
IDS Number:
TO5U8
|
|
ISSN:
0974-9276
|
|
eISSN:
0976-352X
|
|
29-char Source Abbrev.:
BIOSCOPE
|
|
ISO Source Abbrev.:
BioScope S. Asian Screen Stud.
|
|
Source Item Page Count:
28
|
|
Output Date:
2024-07-01
|
| Record 6 of 44 |
|
Title:
Pedagogical challenges of Israel studies in India
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|
Author(s):
Kumaraswamy, PR (Kumaraswamy, P. R.) |
| Source:
JOURNAL OF ISRAELI HISTORY DOI:
10.1080/13531042.2023.2368285 Early Access Date:
JUN 2024 Published Date:
2024 JUN 20 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
40
|
|
Abstract:
Israel Studies in India faces five specific challenges. The presence of a small Jewish population and weaker Zionist sentiments; the absence of Judeo-Christian tradition and unfamiliarity with Jewish historical affinity with the holy land; viewing Israel and its claims through the Islamic prism due to the presence of a large Muslim population; the ideological baggage of framing of Arab-Israeli conflict through the “progressive lens” and the resultant anti-Israeli narrative among the elite; and the limited utility of historical guilt due to the absence of any role or association with the Holocaust or anti-Semitism. Moreover, the four decades of a recognition-without-relations policy of the Indian government has impeded a balanced understanding of Israel and its dilemma vis-& agrave;-vis the outside world. Hence, Israel Studies in India demand a different, innovative, and non-Western approach. |
|
Accession Number:
WOS:001250503300001
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
Judeo-Christian Heritage; Islamic prism; Muslim population; normalization |
Addresses:
[Kumaraswamy, P. R.] Jawaharlal Nehru Univ, New Delhi, India.
[Kumaraswamy, P. R.] JNU, CWAS, SIS, New Delhi 110067, India. |
|
Corresponding Address:
Kumaraswamy, PR (corresponding author), JNU, CWAS, SIS, New Delhi 110067, India. |
|
E-mail Addresses:
kumaraswamy.pr@gmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi |
|
Publisher:
ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
|
|
Publisher Address:
2-4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
|
|
Web of Science Index:
Social Science Citation Index (SSCI); Arts & Humanities Citation Index (A&HCI)
|
|
Web of Science Categories:
History |
|
Research Areas:
History |
|
IDS Number:
UU2J2
|
|
ISSN:
1353-1042
|
|
eISSN:
1744-0548
|
|
29-char Source Abbrev.:
J ISR HIST
|
|
ISO Source Abbrev.:
J. Isr. Hist.
|
|
Source Item Page Count:
15
|
|
Output Date:
2024-07-01
|
| Record 7 of 44 |
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Title:
Agricultural livelihood sustainability assessment among the indigenous communities of Sundarban biosphere reserve in India: a cross-sectional mixed methods approach
|
|
Author(s):
Das, S (Das, Shibu); Sharma, KK (Sharma, Kaushal Kumar); Das, D (Das, Debabrata) |
| Source:
ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY DOI:
10.1007/s10668-024-05008-3 Early Access Date:
JUN 2024 Published Date:
2024 JUN 14 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
103
|
|
Abstract:
Improving the tribal community’s livelihood security is a top priority for the Indian government. This study measured the livelihood security among the tribal community of 19 C.D. blocks (C.D. blocks represent the community development blocks in West Bengal of India. In West Bengal C.D. blocks are the sub district level unit.) in the Sundarban Delta, a backward region in southeast India. No such studies consider the whole tribal community in this fragile ecosystem and deal with their livelihood sustainability. However, none of the studies addressed the integrated agricultural system (crop, fishery and livestock) and measured this region’s sustainable agriculture livelihood security index among the tribal community. The sustainable agriculture livelihood security index (SALSI) is a function of three component indicators, i.e. ecological security index (ESI), social equity index (SEI) and economic efficiency index (EEI). This study has taken 27 indicators related to three components of sustainable agriculture livelihood security index. One-way ANOVA has been used to find the responsible factors present for spatially heterogeneous components of the SALSI. A cross-sectional mixed-method approach was adopted to conduct the study. Interblock spatial variation has been observed in the three aspects of the SALSI. Namkhana (0.57) ranked highest in SALSI, while Kultali (0.35) ranked last. In the case of sub-components, ESI was stronger indices compared to the other two indices, EEI and SEI. Kultali, Jaynagar – II, Canning – I, Basanti, and Sandeshkhali – II blocks had a very low level of sustainability. But, it was highly sustainable in Sagar, Namkhana, and Patharpratima. Results suggested that region-centric, systematic, and proactive approaches are required for sustainable development among the tribal community in this region. The results provide valuable insights for policymakers and relevant stakeholders to facilitate the transformation of C.D. blocks with very low and low sustainability levels. By implementing appropriate policies that address these factors, there is an opportunity to elevate these C.D. blocks to achieve moderate and high levels of agricultural sustainability. This approach is transferable and can be implemented across different scales, not only in other regions within India but also in various developing nations. |
|
Accession Number:
WOS:001246755600002
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
Agrarian indigenous communities; India; Mixed method approach; Sundarban biosphere reserve; Sustainable livelihood |
|
KeyWords Plus:
SOCIAL SUSTAINABILITY; VAISHALI DISTRICT; CLIMATE-CHANGE; FARM-LEVEL; SECURITY; INDICATORS; INDEX; VULNERABILITY; CONSERVATION |
Addresses:
[Das, Shibu; Sharma, Kaushal Kumar] Jawaharlal Nehru Univ, Ctr Study Reg Dev CSRD, Sch Social Sci SSS, New Delhi 110067, India.
[Das, Debabrata] Krishnagar Govt Coll, Coll St, Nadia 741101, West Bengal, India. |
|
Corresponding Address:
Das, S (corresponding author), Jawaharlal Nehru Univ, Ctr Study Reg Dev CSRD, Sch Social Sci SSS, New Delhi 110067, India. |
|
E-mail Addresses:
shibudasgeoku2016@gmail.com; kaushalkumar@mail.jnu.ac.in; debabratakgc@gmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi |
|
Publisher:
SPRINGER
|
|
Publisher Address:
VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Green & Sustainable Science & Technology; Environmental Sciences |
|
Research Areas:
Science & Technology – Other Topics; Environmental Sciences & Ecology |
|
IDS Number:
UF9F8
|
|
ISSN:
1387-585X
|
|
eISSN:
1573-2975
|
|
29-char Source Abbrev.:
ENVIRON DEV SUSTAIN
|
|
ISO Source Abbrev.:
Environ. Dev. Sustain.
|
|
Source Item Page Count:
47
|
|
Output Date:
2024-07-01
|
| Record 8 of 44 |
|
Title:
Plastic pollution and economic growth: some lessons from Japan
|
|
Author(s):
Singha, K (Singha, Komol); Guha, P (Guha, Pradyut); Upadhyay, J (Upadhyay, Jyoti) |
| Source:
ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY DOI:
10.1007/s10668-024-05137-9 Early Access Date:
JUN 2024 Published Date:
2024 JUN 22 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
77
|
|
Abstract:
This study examines the long-term relationship between plastic pollution and economic growth in Japan, using time series data from 1985 to 2021. This study also examines the role of institutions, especially the Japanese informal/social and cultural values, in balancing plastic pollution/waste caused by the country’s rapid economic expansion. The regression results demonstrated that an increase in plastic output/waste in the short-run is related to an increase in GDP per capita, manufacturing sector share of GDP, and population size. However, the quadratic component of lagged GDP per capita is found to be negatively correlated with increased plastic production, providing statistical support for the presence of an inverted U-shaped EKC. Though R&D spending increased plastic waste discharge in the short run, it has since reversed in the long run. Despite its high plastic production and consumption, Japan has become one of the most efficient plastic waste management nations due to its unique socio-cultural habits, which deserves to be replicated worldwide. |
|
Accession Number:
WOS:001252326300003
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
Environment; Economy; Japanese society; Plastic pollution; F64; I15; K32; Q53; Q56; Z13 |
|
KeyWords Plus:
KUZNETS CURVE HYPOTHESIS; ENVIRONMENT; TECHNOLOGY; PROGRESS; WASTE; CHINA; FUEL |
Addresses:
[Singha, Komol] Jawaharlal Nehru Univ, Ctr Econ Studies & Planning, Sch Social Sci 2, New Delhi 110067, India.
[Guha, Pradyut] Sikkim Univ, Dept Econ, Gangtok 737102, India. |
|
Corresponding Address:
Singha, K (corresponding author), Jawaharlal Nehru Univ, Ctr Econ Studies & Planning, Sch Social Sci 2, New Delhi 110067, India. |
|
E-mail Addresses:
hijamkomol@gmail.com; pguha@cus.ac.in; jyotiupadhyay11@gmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; Sikkim University |
|
Publisher:
SPRINGER
|
|
Publisher Address:
VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Green & Sustainable Science & Technology; Environmental Sciences |
|
Research Areas:
Science & Technology – Other Topics; Environmental Sciences & Ecology |
|
IDS Number:
WB1V7
|
|
ISSN:
1387-585X
|
|
eISSN:
1573-2975
|
|
29-char Source Abbrev.:
ENVIRON DEV SUSTAIN
|
|
ISO Source Abbrev.:
Environ. Dev. Sustain.
|
|
Source Item Page Count:
26
|
|
Output Date:
2024-07-01
|
| Record 9 of 44 |
|
Title:
Risk assessment of trace elements in vegetables grown in river Yamuna floodplain in Delhi
|
|
Author(s):
Aithani, D (Aithani, Deeksha); Jyethi, DS (Jyethi, Darpa Saurav); Yadav, AK (Yadav, Amit Kumar); Siddiqui, Z (Siddiqui, Zainab); Khillare, PS (Khillare, Pandit Sudan) |
| Source:
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH Volume:
46 Issue:
6 Article Number:
180 DOI:
10.1007/s10653-024-01948-x Published Date:
2024 JUN |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
2 |
|
Usage Count
(Since 2013):
2 |
|
Cited Reference Count:
37
|
|
Abstract:
Urban agriculture is common in fertile river floodplains of many developing countries. However, there is a risk of contamination in highly polluted regions. This study quantifies health risks associated with the consumption of vegetables grown in the floodplain of the urban river ‘Yamuna’ in the highly polluted yet data-scarce megacity Delhi, India. Six trace elements are analyzed in five kinds of vegetable samples. Soil samples from the cultivation area are also analyzed for elemental contamination. Ni, Mn, and Co are observed to be higher in leafy vegetables than others. Fruit and inflorescence vegetables are found to have higher concentrations of Cr, Pb, and Zn as compared to root vegetables. Transfer Factor indicates that Cr and Co have the highest and least mobility, respectively. Vegetable Pollution Index indicates that contamination levels follow as Cr > Ni > Pb > Zn. Higher Metal Pollution Index of leafy and inflorescence vegetables than root and fruit vegetables indicate that atmospheric deposition is the predominant source. Principal Component Analysis indicates that Pb and Cr have similar sources and patterns in accumulation. Among the analyzed vegetables, radish may pose a non-carcinogenic risk to the age group of 1-5 year. Carcinogenic risk is found to be potentially high due to Ni and Cr accumulation. Consumption of leafy vegetables was found to have relatively less risk than other vegetables due to lower Cr accumulation. Remediation of Cr and Ni in floodplain soil and regular monitoring of elemental contamination is a priority. |
|
Accession Number:
WOS:001225934200028
|
|
PubMed ID:
38696107
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Health risk; Trace element; Urban river floodplain; Vegetables; Yamuna |
|
KeyWords Plus:
HEAVY-METAL CONTAMINATION; HEALTH-RISK; TOXICITY; SOIL; CONSUMPTION; PLANTS |
Addresses:
[Aithani, Deeksha; Yadav, Amit Kumar; Siddiqui, Zainab; Khillare, Pandit Sudan] Jawaharlal Nehru Univ, Sch Environm Sci, Delhi, India.
[Jyethi, Darpa Saurav] Indian Stat Inst, North East Ctr, Theoret & Appl Sci Unit, Tezpur, Assam, India. |
|
Corresponding Address:
Jyethi, DS (corresponding author), Indian Stat Inst, North East Ctr, Theoret & Appl Sci Unit, Tezpur, Assam, India. |
|
E-mail Addresses:
darpa@isine.ac.in |
|
Affiliations:
Jawaharlal Nehru University, New Delhi |
|
Publisher:
SPRINGER
|
|
Publisher Address:
VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Engineering, Environmental; Environmental Sciences; Public, Environmental & Occupational Health; Water Resources |
|
Research Areas:
Engineering; Environmental Sciences & Ecology; Public, Environmental & Occupational Health; Water Resources |
|
IDS Number:
RE2T0
|
|
ISSN:
0269-4042
|
|
eISSN:
1573-2983
|
|
29-char Source Abbrev.:
ENVIRON GEOCHEM HLTH
|
|
ISO Source Abbrev.:
Environ. Geochem. Health
|
|
Source Item Page Count:
14
|
| Funding: |
| Funding Agency | Grant Number |
|
University Grants Commission, Government of India | |
|
|
We are grateful to Mr. Hoshiar Singh, Mr. Dinesh, and Mr. Ankesh for their support in sampling. We thank the Central Instrumentation Facility, School of Environmental Sciences, Jawaharlal Nehru University for analysis of elements by Atomic Absorption Spectrometer. Research fellowship to Deeksha Aithani by University Grants Commission, Government of India is duly acknowledged. The authors are thankful to the Editor and the anonymous reviewers for their comments towards improving the manuscript.
|
|
Output Date:
2024-07-01
|
| Record 10 of 44 |
|
Title:
Estimation of Non-Marine Fractions of Ions in Rainwater at Three Sites of Different Characteristics in Haryana State (India)
|
|
Author(s):
Singh, Y (Singh, Yogender); Katoch, A (Katoch, Ankita); Yadav, S (Yadav, Sudesh); Dhakad, S (Dhakad, Saurabh); Kulshrestha, UC (Kulshrestha, Umesh Chandra) |
| Source:
AEROSOL AND AIR QUALITY RESEARCH Volume:
24 Issue:
6 Article Number:
230252 DOI:
10.4209/aaqr.230252 Published Date:
2024 JUN |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
54
|
|
Abstract:
Non-marine sulphate (SO42-) has a significant influence on the pH of rainwater. This study reports the wet deposition of major ions at three sites having different land use and land cover (LULC) characteristics in Haryana state, located in the agriculturally dominated northwestern part of India. The sites Hisar (urban), Bahadurgarh (industrial), and Meham (semi-urban) had an average pH of rainwater of 5.94, 6.32, and 6.38, respectively. The sum of ionic constituents (i.e., Na+, NH4+, K+, Ca2+, Mg2+, F-, Cl-, NO3-, and SO42-) was found higher at the industrial site (309.9 mu eq L-1) as compared to the urban (225.6 mu eq L-1) and semi-urban (255.7 mu eq L-1) sites with dominant contribution of NH4+ ions. Calculation of ratios of major ions to Na+ to compare the standard Na+ ratios of seawater at all the sites indicated a significant influence of non-marine sources. Source apportionment was carried out using principal component analysis (PCA) which indicated that anthropogenic activities such as coal combustion or industrial emissions were the key sources at the industrial and urban sites. Fertilizer application and its volatilization was observed as a potential source of NH3 at the semi-urban site which is expected due to prominent agricultural activities. Ca2+ and SO42- both were associated significantly with non-marine sources at all three sites. The non-marine fraction was further differentiated into anthropogenic and crustal-associated portions using soil Ca2+ ratios. The anthropogenic/crustal ratios of nss-SO42- were calculated as 0.41, 0.32, and 0.28 at urban, industrial, and semi-urban sites respectively. These ratios were inversely with pH explaining low pH at higher anthropogenic/crustal ratios. This approach of calculation of non-marine crustal associated and anthropogenic SO42- is very important to assess acidification prospects in the region. |
|
Accession Number:
WOS:001249292600002
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Non-marine sulphate; Non-marine chloride; Wet deposition; Source-apportionment |
|
KeyWords Plus:
WET DEPOSITION FLUXES; LONG-RANGE TRANSPORT; CHEMICAL-COMPOSITION; MAJOR IONS; URBAN SITE; ACID-RAIN; NEW-DELHI; PRECIPITATION; NITROGEN; CHEMISTRY |
Addresses:
[Singh, Yogender; Katoch, Ankita; Yadav, Sudesh; Dhakad, Saurabh; Kulshrestha, Umesh Chandra] Jawaharlal Nehru Univ, Sch Environm Sci, New Delhi 110067, India.
[Singh, Yogender] Delhi Univ, Shivaji Coll, Dept Environm Studies, New Delhi 110027, India. |
|
Corresponding Address:
Kulshrestha, UC (corresponding author), Jawaharlal Nehru Univ, Sch Environm Sci, New Delhi 110067, India. |
|
E-mail Addresses:
umeshkulshrestha@gmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; University of Delhi |
|
Publisher:
TAIWAN ASSOC AEROSOL RES-TAAR
|
|
Publisher Address:
CHAOYANG UNIV TECH, DEPT ENV ENG & MGMT, PROD CTR AAQR, NO 168, JIFONG E RD, WUFONG TOWNSHIP, TAICHUNG COUNTY, 41349, TAIWAN
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Environmental Sciences |
|
Research Areas:
Environmental Sciences & Ecology |
|
IDS Number:
UP6D9
|
|
ISSN:
1680-8584
|
|
eISSN:
2071-1409
|
|
29-char Source Abbrev.:
AEROSOL AIR QUAL RES
|
|
ISO Source Abbrev.:
Aerosol Air Qual. Res.
|
|
Source Item Page Count:
17
|
| Funding: |
| Funding Agency | Grant Number |
|
University Grant Commission | |
|
|
The authors would like to thank Jawaharlal Nehru University for providing the necessary facilities and the University Grant Commission for awarding fellowship to carry out this work. Authors are also thankful to NOAA Air Resources Laboratory (http://www.arl.noaa.gov/ready/hysplit4.html) for trajectory calculations. This work is part of DRS-India Network of Prof. U. C. Kulshrestha and UKRI GCRF South Asian Nitrogen Hub project.
|
|
Output Date:
2024-07-01
|
| Record 11 of 44 |
|
Title:
Studies of photocatalytic and optoelectronic properties of microwave synthesized and polyethyleneimine stabilized carbon quantum dots (vol 305, 130830, 2021)
|
|
Author(s):
Ahlawat, A (Ahlawat, Amit); Rana, PS (Rana, Pawan S.); Solanki, PR (Solanki, Pratima R.) |
| Source:
MATERIALS LETTERS Volume:
365 Article Number:
136350 DOI:
10.1016/j.matlet.2024.136350 Published Date:
2024 JUN 15 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
1
|
|
Accession Number:
WOS:001236118000001
|
|
Language:
English |
|
Document Type:
Correction |
Addresses:
[Ahlawat, Amit; Solanki, Pratima R.] Jawaharlal Nehru Univ, Special Ctr NanoSci, New Delhi, India.
[Ahlawat, Amit; Rana, Pawan S.] Deenbandhu Chhotu Ram Univ Sci & Technol, Dept Phys, Murthal 131039, India. |
|
Corresponding Address:
Solanki, PR (corresponding author), Jawaharlal Nehru Univ, Special Ctr NanoSci, New Delhi, India. |
|
E-mail Addresses:
partima@mail.jnu.ac.in |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; Deenbandhu Chhotu Ram University of Science & Technology |
|
Publisher:
ELSEVIER
|
|
Publisher Address:
RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Materials Science, Multidisciplinary; Physics, Applied |
|
Research Areas:
Materials Science; Physics |
|
IDS Number:
SR2R8
|
|
ISSN:
0167-577X
|
|
eISSN:
1873-4979
|
|
29-char Source Abbrev.:
MATER LETT
|
|
ISO Source Abbrev.:
Mater. Lett.
|
|
Source Item Page Count:
1
|
|
Output Date:
2024-07-01
|
| Record 12 of 44 |
|
Title:
Multiscale modeling and prediction of elastic properties of MWCNT- and RHA-reinforced AlP0507 matrix composite
|
|
Author(s):
Srivastava, N (Srivastava, Nitin); Singh, LK (Singh, Lavish Kumar); Yadav, MK (Yadav, Manoj Kumar); Kamesh, B (Kamesh, Bodduru) |
| Source:
JOURNAL OF THE BRAZILIAN SOCIETY OF MECHANICAL SCIENCES AND ENGINEERING Volume:
46 Issue:
6 Article Number:
329 DOI:
10.1007/s40430-024-04919-6 Published Date:
2024 JUN |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
2 |
|
Usage Count
(Since 2013):
2 |
|
Cited Reference Count:
31
|
|
Abstract:
The objective of this study is to utilize numerical modeling techniques to forecast the performance of a novel metal matrix composite and speed up the experimental testing process by reproducing the unique features observed at the micro-scale of the composite material. The matrix material chosen for this study was aluminum P0507 alloy, with multi-walled carbon nanotube (MWCNT) and rice husk ash (RHA) selected as the reinforcements. The reinforcement loading was varied from 1 to 9 vol.%. The representative volume element model in corroboration with the DIGIMAT-FE software was utilized to model, simulate and assess the performance of these composites across different volume fractions and orientations. Both the modulus, elastic and shear, increased monotonously with increase in the CNT and RHA content, whereas the Poisson’s ratio decreased with increase in the reinforcement loading; the changes being more evident in CNT-reinforced composites. On one hand, highest value of E-1 was found in case of aligned inclusions, on the other hand, the highest value of E-2 and E-3 was found for composites containing 2D random orientation type inclusions. As far as shear moduli are concerned, the highest value of G(12) was found for 2D random orientation type, and the highest value of G(23) and G(13) was found in case of 3D random type orientation. The elastic moduli and shear moduli followed the following trend: E-1 > E-2 > E-3 and G(12) > G(13) > G(23). The values of elastic as well as shear moduli for hybrid composite, Al-9 vol.% (CNT + RHA), were found to be higher than that of Al-9 vol.% RHA. For instance, the value of 2D-oriented E-1 increased from 77.15 to 78.40 GPa, and the value of aligned G(13) enhanced from 29.17 to 29.45 GPa. Therefore, it can be concluded that hybrid composites give luxury to fabricate components with tailored properties at a lower cost. |
|
Accession Number:
WOS:001214193600001
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Aluminum alloy P0507; Multi-walled carbon nanotube; Rice husk ash; Representative volume element; Digimat; Elastic property |
Addresses:
[Srivastava, Nitin; Kamesh, Bodduru] Sharda Univ, Dept Mech Engn, Greater Noida, Uttar Pradesh, India.
[Singh, Lavish Kumar] Jawaharlal Nehru Univ, Sch Engn, New Delhi 110067, India.
[Yadav, Manoj Kumar] Ajay Kumar Garg Engn Coll, Dept Mech Engn, Ghaziabad, Uttar Pradesh, India. |
|
Corresponding Address:
Singh, LK (corresponding author), Jawaharlal Nehru Univ, Sch Engn, New Delhi 110067, India. |
|
E-mail Addresses:
lavish.singh2011@gmail.com |
|
Affiliations:
Sharda University; Jawaharlal Nehru University, New Delhi |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Srivastava, Nitin | | 0000-0002-2311-3521 |
|
|
Publisher:
SPRINGER HEIDELBERG
|
|
Publisher Address:
TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Engineering, Mechanical |
|
Research Areas:
Engineering |
|
IDS Number:
PL3L4
|
|
ISSN:
1678-5878
|
|
eISSN:
1806-3691
|
|
29-char Source Abbrev.:
J BRAZ SOC MECH SCI
|
|
ISO Source Abbrev.:
J. Braz. Soc. Mech. Sci. Eng.
|
|
Source Item Page Count:
12
|
|
Output Date:
2024-07-01
|
| Record 13 of 44 |
|
Title:
Unveiling the secretome of <i>Penicillium fuscoglaucum</i> JAM-1 for efficient dual substrate degradation and waste valorization
|
|
Author(s):
Joshi, N (Joshi, Namrata); Grewal, J (Grewal, Jasneet); Stasiuk, R (Stasiuk, Robert); Drewniak, L (Drewniak, Lukasz); Pranaw, K (Pranaw, Kumar) |
| Source:
BIOMASS CONVERSION AND BIOREFINERY DOI:
10.1007/s13399-024-05809-6 Early Access Date:
JUN 2024 Published Date:
2024 JUN 15 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
50
|
|
Abstract:
In the pursuit of cost-effective and superior enzymes crucial for the efficient hydrolysis of diverse lignocellulosic biomasses, filamentous fungi have emerged as key candidates for bioprospecting endeavors. In our exploration for potent lignocellulosic biomass degraders, we have identified a strain of Penicillium fuscoglaucum JAM-1, showcasing multipurpose hydrolase capabilities in its secretome. During fermentation, P. fuscoglaucum JAM-1 effectively utilized rapeseed cake (RSC), resulting in improved enzymatic activities, including xylanase (612 U/gds), beta-glucosidase (264 U/gds), endoglucanase (102 U/gds), FPase (21.3 U/gds), and exo-polygalacturonase (49.17 U/gds), as compared to pine sawdust (PSD). Secretome profiling revealed a protein abundance totaling 435 and 120 proteins during RSC and PSD utilization, respectively. The major component of carbohydrate-active enzymes (CAZymes) consists of cellulose-degrading proteins, including endoglucanases (GH5, GH7), beta-glucosidases (GH1, GH3, GH17), and cellobiohydrolases (GH6, GH7). Correspondingly, hemicellulose-degrading enzymes were present, encompassing endo-1,4-xylanase (GH10), alpha/beta-galactosidase (GH27, GH35, GH36), alpha/beta-mannosidases (GH38, GH2, GH47, GH5), and alpha-l-arabinofuranosidase (GH43, GH62, GH51, GH54) and carbohydrate-active auxiliary activities enzymes, such as AA9 (formerly known as GH61) lytic polysaccharide monooxygenase (LPMO). Upon application to fruit waste, the crude enzyme demonstrated higher saccharification potential compared to commercial cellulase (Cellic CTec2). Specifically, the crude enzyme yielded 565 mg/g of reducing sugar within 72 h, outperforming Cellic CTec2, which yielded 352 mg/g under identical conditions. A comprehensive comparative analysis of enzyme workings, activities, and secretome profiling underscores P. fuscoglaucum JAM-1 as a potent cellulase producer, showcasing its potential to boost lignocellulose biodegradation. These findings highlight the practical applications of the P. fuscoglaucum JAM-1 in various industrial processes, suggesting its role as a valuable candidate for further exploration and exploitation in biotechnological applications. |
|
Accession Number:
WOS:001248310200001
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
Penicillium; Enzymatic hydrolysis; Rapeseed cake; Pine sawdust; Secretome; Orange peel waste |
|
KeyWords Plus:
CELLULASES; LIPASE |
Addresses:
[Joshi, Namrata; Grewal, Jasneet; Drewniak, Lukasz; Pranaw, Kumar] Univ Warsaw, Inst Microbiol, Fac Biol, Dept Environm Microbiol & Biotechnol, Miecznikowa 1, PL-02096 Warsaw, Poland.
[Stasiuk, Robert] Univ Warsaw, Inst Microbiol, Fac Biol, Dept Geomicrobiol, Miecznikowa 1, PL-02096 Warsaw, Poland.
[Pranaw, Kumar] Jawaharlal Nehru Univ, Sch Environm Sci, New Delhi 110067, India. |
Corresponding Address:
Pranaw, K (corresponding author), Univ Warsaw, Inst Microbiol, Fac Biol, Dept Environm Microbiol & Biotechnol, Miecznikowa 1, PL-02096 Warsaw, Poland.
Pranaw, K (corresponding author), Jawaharlal Nehru Univ, Sch Environm Sci, New Delhi 110067, India. |
|
E-mail Addresses:
kpranaw@gmail.com |
|
Affiliations:
University of Warsaw; University of Warsaw; Jawaharlal Nehru University, New Delhi |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
PRANAW, KUMAR | | 0000-0002-6073-8635 |
|
|
Publisher:
SPRINGER HEIDELBERG
|
|
Publisher Address:
TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Energy & Fuels; Engineering, Chemical |
|
Research Areas:
Energy & Fuels; Engineering |
|
IDS Number:
UL8Q8
|
|
ISSN:
2190-6815
|
|
eISSN:
2190-6823
|
|
29-char Source Abbrev.:
BIOMASS CONVERS BIOR
|
|
ISO Source Abbrev.:
Biomass Convers. Biorefinery
|
|
Source Item Page Count:
12
|
| Funding: |
| Funding Agency | Grant Number |
|
Fundacja na rzecz Nauki Polskiej | |
|
|
The authors thank Abhishek Agarwal, Laboratory of Functional and Structural Genomics, Centre of New Technologies, University of Warsaw, for helping implement the R script for creating a graph.
|
|
Open Access:
hybrid
|
|
Output Date:
2024-07-01
|
| Record 14 of 44 |
|
Title:
Comparative Transcriptomics Reveals Novel Spatial Gene Expression Profiles in Cotton (<i>Gossypium hirsutum</i> L.) Under Herbivory and Drought Stress
|
|
Author(s):
Bihani, D (Bihani, Dikshika); Khuman, A (Khuman, Aniruddhabhai); Chaudhary, B (Chaudhary, Bhupendra) |
| Source:
JOURNAL OF PLANT GROWTH REGULATION DOI:
10.1007/s00344-024-11362-3 Early Access Date:
JUN 2024 Published Date:
2024 JUN 18 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
73
|
|
Abstract:
Cotton is the major natural fiber-producing crop, contributing significantly to the global textile economy. However, the cotton crop encounters several biotic and abiotic stress challenges globally, causing substantial annual yield loss. Plant responses to such diverse stress conditions involve intricate molecular and physiological modifications at the cellular level. Here, we employed a genomics approach to illustrate comprehensive spatial transcriptomic profiles in response to various insect infestations, including aphids (Aphis gossypii), cotton boll weevils (Anthonomus grandis), cotton bollworms (Helicoverpa armigera), whiteflies (Bemisia tabaci), and drought stress. Comparative temporal expression analysis with a strict log-fold change threshold (> 2.0) revealed distinct gene expression patterns in different tissues of cotton plants, with selected pivotal ‘stress-general’ and ‘stress-specific’ genes involved in plant defense mechanisms against various infestations and drought conditions. The expression of at least 5 insect-general transcription factor-encoding genes, WRKY28, WRKY40, WRKY53, ERF4, and ERF5, was highly upregulated across cotton leaf tissues infested by aphids, cotton bollworms, and whiteflies. Additionally, a set of highly upregulated ‘stress-specific’ genes, including GH3.1, ACS1, CYP74A, TIFY10A, BHLH25, ABR1, and ERF025, were identified especially after a 6-h period of cotton bollworm infestation. Similarly, various sets of such ‘stress-specific’ spatially upregulated genes were identified across diverse insect infestations. Functional annotation of differentially expressed genes revealed the upregulation of various defense-related functions such as stress hormone signal transduction, MAPK signaling pathway, and biosynthesis of secondary metabolites, orchestrating the plant’s defense mechanisms. Further, spatiotemporal expression analysis of ‘stress-general’ genes in response to abiotic stresses revealed that GhWRKY28 was highly upregulated in response to both biotic and abiotic stress conditions. The findings suggested that the identified ‘stress-general’ genes could serve as suitable candidates for manipulating crops for multiple stress resistance/tolerance. |
|
Accession Number:
WOS:001250320000001
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
Cotton; Transcriptome; Insect infestation; Drought tolerance; Pest management |
|
KeyWords Plus:
ENHANCES RESISTANCE; INSECT RESISTANCE; ARABIDOPSIS; OVEREXPRESSION; JASMONATE; INFESTATION; PATHOGEN; DEFENSE; MEMBER; ACID |
Addresses:
[Bihani, Dikshika; Khuman, Aniruddhabhai; Chaudhary, Bhupendra] Gautam Buddha Univ, Sch Biotechnol, Greater Noida 201312, Uttar Pradesh, India.
[Chaudhary, Bhupendra] Jawaharlal Nehru Univ, Sch Life Sci, New Delhi 110067, India. |
Corresponding Address:
Chaudhary, B (corresponding author), Gautam Buddha Univ, Sch Biotechnol, Greater Noida 201312, Uttar Pradesh, India.
Chaudhary, B (corresponding author), Jawaharlal Nehru Univ, Sch Life Sci, New Delhi 110067, India. |
|
E-mail Addresses:
bhupendra@mail.jnu.ac.in |
|
Affiliations:
Gautam Buddha University; Jawaharlal Nehru University, New Delhi |
|
Publisher:
SPRINGER
|
|
Publisher Address:
ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Plant Sciences |
|
Research Areas:
Plant Sciences |
|
IDS Number:
UT5K0
|
|
ISSN:
0721-7595
|
|
eISSN:
1435-8107
|
|
29-char Source Abbrev.:
J PLANT GROWTH REGUL
|
|
ISO Source Abbrev.:
J. Plant Growth Regul.
|
|
Source Item Page Count:
20
|
| Funding: |
| Funding Agency | Grant Number |
|
Science and Engineering Research Board (SERB), Government of India |
EMR/2016/005497
|
|
Council of Scientific and Industrial Research (CSIR), Government of India |
38(1298)/11/EMR-II
|
|
Department of Biotechnology (DBT), Government of India |
BT/PR8727/AGR/36/777/2013
|
|
|
This work was supported by the Science and Engineering Research Board (SERB), Government of India (Grant No. EMR/2016/005497), Council of Scientific and Industrial Research (CSIR), Government of India (Grant No. 38(1298)/11/EMR-II), and Department of Biotechnology (DBT), Government of India (Grant No. BT/PR8727/AGR/36/777/2013). The authors are thankful to the funding agencies for providing financial support to carry out this research.
|
|
Output Date:
2024-07-01
|
| Record 15 of 44 |
|
Title:
Non-Debye to Debye spectral shift in solid solutions of orientationally disordered crystals
|
|
Author(s):
Singh, AK (Singh, Abhishek K.) |
| Source:
PHYSICAL REVIEW E Volume:
109 Issue:
6 Article Number:
065003 DOI:
10.1103/PhysRevE.109.065003 Published Date:
2024 JUN 13 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
43
|
|
Abstract:
Debye relaxation is a simple and unique physical mechanism by which a macroscopic orientational polarization decays monoexponentially with time. However, the very existence of the Debye process in complex systems such as water, aqueous solutions, and monohydroxyl alcohols, among others, is puzzling to date and their microscopic origin is still ambiguously explained. In order to shed light on some of these aspects, orientational dynamics of an orientationally disordered dipolar crystal with an identically structured nonpolar matrix has been studied in the form of solid solutions. A crossover from non-Debye to Debye-type spectral behavior has been observed with increasing concentration of the nonpolar matrix in the solid solutions. Analysis of the dynamic response shows that the evolution of cooperativity and spatial heterogeneity with concentration of nonpolar matrix is responsible for the observed trends. The results not only authenticate a possible mechanism of the Debye process as originating from localized orientational fluctuations due to molecular dipoles but also shed light on the evolution of non-Debye characteristics in these systems. |
|
Accession Number:
WOS:001247491400008
|
|
Language:
English |
|
Document Type:
Article |
|
KeyWords Plus:
DIELECTRIC-RELAXATION; PLASTIC CRYSTALS; DYNAMICS; PHASE; LIQUID |
Addresses:
[Singh, Abhishek K.] Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India.
[Singh, Abhishek K.] Ohio State Univ, Sch Med, Columbus, OH 43210 USA. |
Corresponding Address:
Singh, AK (corresponding author), Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India.
Singh, AK (corresponding author), Ohio State Univ, Sch Med, Columbus, OH 43210 USA. |
|
E-mail Addresses:
abhishekjnu00@gmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; University System of Ohio; Ohio State University |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Singh, Abhishek K. | | 0000-0003-3895-198X |
|
|
Publisher:
AMER PHYSICAL SOC
|
|
Publisher Address:
ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Physics, Fluids & Plasmas; Physics, Mathematical |
|
Research Areas:
Physics |
|
IDS Number:
UI7K8
|
|
ISSN:
2470-0045
|
|
eISSN:
2470-0053
|
|
29-char Source Abbrev.:
PHYS REV E
|
|
ISO Source Abbrev.:
Phys. Rev. E
|
|
Source Item Page Count:
7
|
|
Output Date:
2024-07-01
|
| Record 16 of 44 |
|
Title:
Cellular Transport and Multifaceted Roles of Jasmonates in Nutrient Deficiency Response in Plants
|
|
Author(s):
Kamali, S (Kamali, Saravanappriyan); Sonkar, K (Sonkar, Kamankshi); Singh, A (Singh, Amarjeet) |
| Source:
JOURNAL OF PLANT GROWTH REGULATION DOI:
10.1007/s00344-024-11364-1 Early Access Date:
JUN 2024 Published Date:
2024 JUN 6 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
127
|
|
Abstract:
Jasmonates (JAs) are well documented for their role in plant defense and growth regulation. Cellular transport of JAs during their biosynthesis and signaling constitutes an important layer of their functional regulation. However, most of the information about JAs transport has been gathered in recent years. Therefore, understanding the mechanism of intracellular transport of JAs in plants is of great importance to comprehend their function. In addition, in recent years, JAs have emerged as key regulators of nutrient deficiency response in plants. Under nutrient deficiency, plants show unique adaptive responses, including altered root growth, remodeling of root system architecture (RSA), triggering nutrient uptake-related genes, and activation of nutrient transporters. JAs have been found to regulate these responses in relation to the variable availability of macro- and micronutrients. Evidence indicates that in response to deficiencies of macronutrients such as nitrogen (N), phosphorus (P), and potassium (K+), the JA biosynthesis pathway is modulated, leading to higher JA accumulation. Furthermore, the JA-signaling pathway has been shown to regulate nutrient deficiency-related transcription factors, transporters, and RSA for optimum plant development. In this review, recent developments and updates on molecular mechanisms of cellular transport of JAs during JA biosynthesis and signaling are presented. In addition, new insights on involvement of JAs in nutrient uptake, homeostasis, deficiency response, and plant development have been provided. |
|
Accession Number:
WOS:001243283300002
|
|
Language:
English |
|
Document Type:
Review; Early Access |
|
Author Keywords:
Deficiency; Homeostasis; Jasmonates; Macronutrients; Micronutrients; Root system architecture; Transport; Uptake |
|
KeyWords Plus:
BINDING CASSETTE TRANSPORTER; PEROXISOMAL ABC TRANSPORTER; TENDRIL-COILING RESPONSE; TRANSCRIPTION FACTOR; METHYL JASMONATE; CIS-JASMONE; 12-OXO-PHYTODIENOIC ACID; ARABIDOPSIS-THALIANA; SEED-GERMINATION; GENE-EXPRESSION |
Addresses:
[Kamali, Saravanappriyan; Sonkar, Kamankshi; Singh, Amarjeet] Natl Inst Plant Genome Res, New Delhi 110067, India.
[Singh, Amarjeet] Jawaharlal Nehru Univ, Sch Life Sci, New Delhi 110067, India. |
Corresponding Address:
Singh, A (corresponding author), Natl Inst Plant Genome Res, New Delhi 110067, India.
Singh, A (corresponding author), Jawaharlal Nehru Univ, Sch Life Sci, New Delhi 110067, India. |
|
E-mail Addresses:
amarjeetsingh@jnu.ac.in |
|
Affiliations:
Department of Biotechnology (DBT) India; National Institute of Plant Genome Research (NIPGR); Jawaharlal Nehru University, New Delhi |
|
Publisher:
SPRINGER
|
|
Publisher Address:
ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Plant Sciences |
|
Research Areas:
Plant Sciences |
|
IDS Number:
TS6H9
|
|
ISSN:
0721-7595
|
|
eISSN:
1435-8107
|
|
29-char Source Abbrev.:
J PLANT GROWTH REGUL
|
|
ISO Source Abbrev.:
J. Plant Growth Regul.
|
|
Source Item Page Count:
16
|
| Funding: |
| Funding Agency | Grant Number |
|
National Institute of Plant Genome Research (NIPGR) core grant | |
|
Science and Engineering Research Board (SERB)-Department of Science and Technology (DST), Government of India |
EEQ/2022/000062
|
|
DBT-BUILDER project |
DBT-BUILDER BT/INF/22/SP45382/2022
|
|
Council of Scientific and Industrial Research (CSIR), India | |
|
|
We acknowledge financial support from the National Institute of Plant Genome Research (NIPGR) core grant, research grant from Science and Engineering Research Board (SERB)-Department of Science and Technology (DST), Government of India (Grant No. EEQ/2022/000062), and from the DBT-BUILDER project (DBT-BUILDER BT/INF/22/SP45382/2022). SK and KS are thankful to Council of Scientific and Industrial Research (CSIR), India for research fellowships.
|
|
Output Date:
2024-07-01
|
| Record 17 of 44 |
|
Title:
Concurrent improvement of rice grain yield and abiotic stress tolerance by overexpression of cytokinin activating enzyme LONELY GUY (OsLOG)
|
|
Author(s):
Rathore, RS (Rathore, Ray Singh); Mishra, M (Mishra, Manjari); Pareek, A (Pareek, Ashwani); Singla-Pareek, SL (Singla-Pareek, Sneh Lata) |
| Source:
PLANT PHYSIOLOGY AND BIOCHEMISTRY Volume:
211 Article Number:
108635 DOI:
10.1016/j.plaphy.2024.108635 Published Date:
2024 JUN |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
88
|
|
Abstract:
Meristem activity is important for normal plant growth as well as adaptive plastic development under abiotic stresses. Cytokinin has been recognized to have a major role in regulating meristem function which is controlled by cytokinin activating enzymes by fine-tuning the concentrations and spatial distribution of its bioactive forms. It was previously reported that LONELY GUY (LOG) acts in the direct activation pathway of cytokinin in rice shoot meristems. LOG has a cytokinin specific phosphoribohydrolase activity, which transforms inactive cytokinin nucleotides into active free bases. Here, we explored the role of OsLOG in controlling meristem activity mediated by cytokinin and its effects on growth, development, and stress resilience of rice plants. Overexpression of OsLOG in rice led to significant alterations in cytokinin levels in the inflorescence meristem, leading to enhanced plant growth, biomass and grain yield under both non-stress as well as stress conditions such as drought and salinity. Moreover, our study provides insight into how overexpression of OsLOG improves the ability of plants to withstand stress. The OsLOG-overexpressing lines exhibit reduced accumulation of H2O2 along with elevated antioxidant enzyme activities, thereby maintaining better redox homeostasis under stress conditions. This ultimately reduces the negative impact of stresses on grain yield and improves harvest index, as evidenced by observations in the OsLOG-overexpressing lines. In summary, our study emphasizes the diverse role of OsLOG, not only in regulating plant growth and yield via cytokinin but also in enhancing adaptability to abiotic stresses. This highlights its potential to improve crop yield and promote sustainable agriculture. |
|
Accession Number:
WOS:001235979700001
|
|
PubMed ID:
38688114
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Abiotic stresses; Cytokinin; Hydrogen peroxide; Reactive oxygen species; Rice; Yield |
|
KeyWords Plus:
DROUGHT TOLERANCE; ARABIDOPSIS; GENES; EXPRESSION; BIOSYNTHESIS; PLANTS; METABOLISM; SENESCENCE; AUXIN; HOMEOSTASIS |
Addresses:
[Rathore, Ray Singh; Mishra, Manjari; Singla-Pareek, Sneh Lata] Int Ctr Genet Engn & Biotechnol, Plant Stress Biol, New Delhi 110067, India.
[Pareek, Ashwani] Jawaharlal Nehru Univ, Sch Life Sci, Stress Physiol & Mol Biol Lab, New Delhi 110067, India. |
|
Corresponding Address:
Singla-Pareek, SL (corresponding author), Int Ctr Genet Engn & Biotechnol, Plant Stress Biol, New Delhi 110067, India. |
|
E-mail Addresses:
sneh@icgeb.res.in |
|
Affiliations:
Department of Biotechnology (DBT) India; International Center for Genetic Engineering & Biotechnology (ICGEB); International Center for Genetic Engineering & Biotechnology (ICGEB), New Delhi; Jawaharlal Nehru University, New Delhi |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Pareek, Ashwani | | 0000-0002-2923-0681 |
|
|
Publisher:
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
|
|
Publisher Address:
65 RUE CAMILLE DESMOULINS, CS50083, 92442 ISSY-LES-MOULINEAUX, FRANCE
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Plant Sciences |
|
Research Areas:
Plant Sciences |
|
IDS Number:
SQ7J6
|
|
ISSN:
0981-9428
|
|
eISSN:
1873-2690
|
|
29-char Source Abbrev.:
PLANT PHYSIOL BIOCH
|
|
ISO Source Abbrev.:
Plant Physiol. Biochem.
|
|
Source Item Page Count:
13
|
| Funding: |
| Funding Agency | Grant Number |
|
ICGEB, New Delhi, India | |
|
Department of Science Technology (DST) |
IF160321
|
|
|
This work was supported by the internal funds of ICGEB, New Delhi, India. R.S.R. thanks Department of Science Technology (DST) for Inspire Fellowship (IF160321) .
|
|
Output Date:
2024-07-01
|
| Record 18 of 44 |
|
Title:
<SUP>1</SUP>H, <SUP>15</SUP>N and <SUP>13</SUP>C resonance backbone and side-chain assignments and secondary structure determination of the BRCT domain of <i>Mtb</i> LigA
|
|
Author(s):
Vaishnav, J (Vaishnav, Jayanti); Ampapathi, RS (Ampapathi, Ravi Sankar) |
| Source:
BIOMOLECULAR NMR ASSIGNMENTS Volume:
18 Issue:
1 Pages:
105-109 DOI:
10.1007/s12104-024-10175-5 Published Date:
2024 JUN |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
24
|
|
Abstract:
The BRCA1 carboxyl-terminal (BRCT) domain, an evolutionarily conserved structural motif, is ubiquitous in a multitude of proteins spanning prokaryotic and eukaryotic organisms. In Mycobacterium tuberculosis (Mtb), BRCT domain plays a pivotal role in the catalytic activity of the NAD+-dependent DNA ligase (LigA). LigA is pivotal in DNA replication, catalyzing the formation of phosphodiester bonds in Okazaki fragments and repairing single-strand breaks in damaged DNA, essential for the survival of Mtb. Structural and functional aspects of LigA unveil its character as a highly modular protein, undergoing substantial conformational changes during its catalytic cycle. Although the BRCT domain of Mtb LigA plays an essential role in DNA binding and protein-protein interactions, the precise mechanism of action remains poorly understood. Unravelling the structure of the BRCT domain holds the promise of advancing our understanding of this pivotal domain. Additionally, it will facilitate further exploration of the protein-protein interactions and enhance our understanding of inter domain interactions within LigA, specifically between BRCT and the Adenylation domain. In this study, we demonstrate the overexpression of the BRCT domain of Mtb LigA and conduct its analysis using solution NMR spectroscopy, revealing a well-folded structure and we present the nearly complete chemical shift assignments of both backbone and sidechains. In addition, a secondary structure prediction by TALOS N predicts BRCT consisting of 3 alpha-helices and 4 beta-sheets, closely resembling the typical structural topology of most BRCT domains. |
|
Accession Number:
WOS:001217612300009
|
|
PubMed ID:
38689205
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
BRCT domain; LigA; Mycobacterium tuberculosis; NAD(+); DNA repair |
|
KeyWords Plus:
NAD(+)-DEPENDENT DNA-LIGASE; MYCOBACTERIUM-TUBERCULOSIS; RV3014C |
Addresses:
[Vaishnav, Jayanti; Ampapathi, Ravi Sankar] CSIR Cent Drug Res Inst, Sophisticated Analyt Instrumentat Facil & Res SAIF, Lucknow 226031, Uttar Pradesh, India.
[Vaishnav, Jayanti; Ampapathi, Ravi Sankar] Jawaharlal Nehru Univ, New Delhi 110067, India.
[Ampapathi, Ravi Sankar] Acad Sci & Innovat Res, Ghaziabad 201002, Uttar Pradesh, India. |
Corresponding Address:
Ampapathi, RS (corresponding author), CSIR Cent Drug Res Inst, Sophisticated Analyt Instrumentat Facil & Res SAIF, Lucknow 226031, Uttar Pradesh, India.
Ampapathi, RS (corresponding author), Jawaharlal Nehru Univ, New Delhi 110067, India.
Ampapathi, RS (corresponding author), Acad Sci & Innovat Res, Ghaziabad 201002, Uttar Pradesh, India. |
|
E-mail Addresses:
ravi_sa@cdri.res.in |
|
Affiliations:
Council of Scientific & Industrial Research (CSIR) – India; CSIR – Central Drug Research Institute (CDRI); Jawaharlal Nehru University, New Delhi; Academy of Scientific & Innovative Research (AcSIR) |
|
Publisher:
SPRINGER
|
|
Publisher Address:
VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Biophysics; Spectroscopy |
|
Research Areas:
Biophysics; Spectroscopy |
|
IDS Number:
PY3Y0
|
|
ISSN:
1874-2718
|
|
eISSN:
1874-270X
|
|
29-char Source Abbrev.:
BIOMOL NMR ASSIGN
|
|
ISO Source Abbrev.:
Biomol. NMR Assign.
|
|
Source Item Page Count:
5
|
| Funding: |
| Funding Agency | Grant Number |
|
CSIR-Central Drug Research Institute |
10775
|
|
ICMR, New Delhi | |
|
|
JV is thankful to ICMR, New Delhi for fellowship. Authors are thankful to DST for 700 MHz Facility of SAIF at CDRI. The CDRI communication number allotted to this manuscript is 10775.
|
|
Output Date:
2024-07-01
|
| Record 19 of 44 |
|
Title:
Diosmetin: A dietary flavone as modulator of signaling pathways in cancer progression
|
|
Author(s):
Raza, W (Raza, Waseem); Meena, A (Meena, Abha); Luqman, S (Luqman, Suaib) |
| Source:
MOLECULAR CARCINOGENESIS DOI:
10.1002/mc.23774 Early Access Date:
JUN 2024 Published Date:
2024 JUN 18 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
104
|
Abstract:
Flavonoids, constituting the most extensive category of polyphenols, founds in a variety of plants and comprise over 9000 compounds. Diosmetin, O-methylated flavone (3′,5,7-trihydroxy-4′-methoxyflavone) of flavonoid aglycone diosmin have witnessed a significant surge in recent years. Many studies showed that flavonoids induced cytotoxicity in different organ specific cancer types. Thus, current review evaluates the anticancer potential of diosmetin and shed light on its mechanism of action such as cell cycle regulation, apoptosis via both intrinsic and extrinsic pathway, autophagy and tumour progression and metastasis. It also provides comprehensive analysis of different cancer targets and their role in breast, colon, hepatic, gliomas, leukemia, lung, prostate and skin cancer. Combination studies of diosmetin to improve drug sensitivity and reduce toxicity towards normal cells has been also discussed. Besides, in vitro studies, present review also discuss the anticancer potential of diosmetin on xenograft mice model. Different natural sources of diosmetin, limitations, pharmacokinetic analysis and toxicity study also summarized in current review. The emphasis on enhancing solubility and permeability for clinical utility has been thoroughly highlighted with particular attention given to the utilization of nano formulations to overcome existing barriers. At last, in-depth analysis of current challenges and a forward-looking perspective deliberated to address the existing gaps and position it as a promising lead compound for clinical applications in cancer treatment. This discussion is boosted by diosmetin’s potential anticancer properties on different cancers, makes valuable candidates in the ongoing quest for effective therapeutic interventions against cancer.
Diosmetin regulates cancer progression by up/downregulating various cancer-associated signaling pathways. image |
|
Accession Number:
WOS:001248787100001
|
|
PubMed ID:
38888206
|
|
Language:
English |
|
Document Type:
Review; Early Access |
|
Author Keywords:
apoptosis; cancer; cell cycle; diosmetin; metastasis |
|
KeyWords Plus:
CELL-CYCLE REGULATION; DEATH PATHWAYS; AERIAL PARTS; IN-VITRO; KAPPA-B; APOPTOSIS; PROLIFERATION; ARREST; SIZE; CONSTITUENTS |
Addresses:
[Raza, Waseem; Meena, Abha; Luqman, Suaib] CSIR Cent Inst Med & Aromat Plants, Bioprospect & Prod Dev Div, Lucknow 226015, Uttar Pradesh, India.
[Raza, Waseem] Jawaharlal Nehru Univ, New Delhi, India.
[Meena, Abha; Luqman, Suaib] Acad Sci & Innovat Res AcSIR, Ghaziabad, India. |
|
Corresponding Address:
Meena, A (corresponding author), CSIR Cent Inst Med & Aromat Plants, Bioprospect & Prod Dev Div, Lucknow 226015, Uttar Pradesh, India. |
|
E-mail Addresses:
a.meena@cimap.res.in |
|
Affiliations:
Council of Scientific & Industrial Research (CSIR) – India; CSIR – Central Institute of Medicinal & Aromatic Plants (CIMAP); Jawaharlal Nehru University, New Delhi; Academy of Scientific & Innovative Research (AcSIR) |
|
Publisher:
WILEY
|
|
Publisher Address:
111 RIVER ST, HOBOKEN 07030-5774, NJ USA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Biochemistry & Molecular Biology; Oncology |
|
Research Areas:
Biochemistry & Molecular Biology; Oncology |
|
IDS Number:
UN6V4
|
|
ISSN:
0899-1987
|
|
eISSN:
1098-2744
|
|
29-char Source Abbrev.:
MOL CARCINOGEN
|
|
ISO Source Abbrev.:
Mol. Carcinog.
|
|
Source Item Page Count:
16
|
| Funding: |
| Funding Agency | Grant Number |
|
CSIR-Central Institute of Medicinal and Aromatic Plants |
DU2/MLP-11
|
|
Council of Scientific & Industrial Research (CSIR), New Delhi | |
|
|
We appreciate the Director, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, for providing us with research-related facilities. WR is thankful to the Council of Scientific & Industrial Research (CSIR), New Delhi, for the Senior Research Fellowship. CSIR-CIMAP (DU2/MLP-11).
|
|
Output Date:
2024-07-01
|
| Record 20 of 44 |
|
Title:
Newcomers navigating the welfare state: experiences of immigrants and street-level bureaucrats with Belgium’s social assistance system
|
|
Author(s):
Panneer, S (Panneer, Sigamani); Thomas, S (Thomas, Sildia) |
| Source:
EUROPEAN JOURNAL OF SOCIAL WORK DOI:
10.1080/13691457.2024.2362700 Early Access Date:
JUN 2024 Published Date:
2024 JUN 8 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
0
|
|
Accession Number:
WOS:001242479100001
|
|
Language:
English |
|
Document Type:
Book Review; Early Access |
Addresses:
[Panneer, Sigamani; Thomas, Sildia] Jawaharlal Nehru Univ, Ctr Study Law & Governance, New Delhi, India.
[Panneer, Sigamani; Thomas, Sildia] Assam Univ, Dept Social Work, Silchar, India. |
Corresponding Address:
Panneer, S (corresponding author), Jawaharlal Nehru Univ, Ctr Study Law & Governance, New Delhi, India.
Panneer, S (corresponding author), Assam Univ, Dept Social Work, Silchar, India. |
|
E-mail Addresses:
sigamani@mail.jnu.ac.in |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; Assam University |
|
Publisher:
ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
|
|
Publisher Address:
2-4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
|
|
Web of Science Index:
Social Science Citation Index (SSCI)
|
|
Web of Science Categories:
Social Work |
|
Research Areas:
Social Work |
|
IDS Number:
TP5O9
|
|
ISSN:
1369-1457
|
|
eISSN:
1468-2664
|
|
29-char Source Abbrev.:
EUR J SOC WORK
|
|
ISO Source Abbrev.:
Eur. J. Soc. Work
|
|
Source Item Page Count:
3
|
|
Output Date:
2024-07-01
|
| Record 21 of 44 |
|
Title:
The role of nucleotide opening dynamics in facilitated target search by DNA-repair proteins
|
|
Author(s):
Mishra, SK (Mishra, Sujeet Kumar); Sangeeta (Sangeeta); Heermann, DW (Heermann, Dieter W.); Bhattacherjee, A (Bhattacherjee, Arnab) |
| Source:
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS Volume:
1867 Issue:
2 Article Number:
195026 DOI:
10.1016/j.bbagrm.2024.195026 Published Date:
2024 JUN |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
55
|
|
Abstract:
Preserving the genomic integrity stands a fundamental necessity, primarily achieved by the DNA repair proteins through their continuous patrolling on the DNA in search of lesions. However, comprehending how even a single base-pair lesion can be swiftly and specifically recognized amidst millions of base-pair sites remains a formidable challenge. In this study, we employ extensive molecular dynamics simulations using an appropriately tuned model of both protein and DNA to probe the underlying molecular principles. Our findings reveal that the dynamics of a non-canonical base generate an entropic signal that guides the one-dimensional search of a repair protein, thereby facilitating the recognition of the lesion site. The width of the funnel perfectly aligns with the one-dimensional diffusion length of DNAbinding proteins. The generic mechanism provides a physical basis for rapid recognition and specificity of DNA damage sensing and recognition. |
|
Accession Number:
WOS:001232240100001
|
|
PubMed ID:
38641240
|
|
Language:
English |
|
Document Type:
Article |
|
KeyWords Plus:
IMINO PROTON-EXCHANGE; MOLECULAR-DYNAMICS; GENERAL MECHANISM; MISMATCH REPAIR; FREE-ENERGY; BASE; RECOGNITION; PATHWAYS; CONFORMATION; LOCATION |
Addresses:
[Mishra, Sujeet Kumar; Sangeeta; Bhattacherjee, Arnab] Jawaharlal Nehru Univ, Sch Computat & Integrat Sci, New Delhi 110067, India.
[Heermann, Dieter W.; Bhattacherjee, Arnab] Heidelberg Univ, Inst Theoret Phys, Heidelberg, Germany. |
Corresponding Address:
Bhattacherjee, A (corresponding author), Jawaharlal Nehru Univ, Sch Computat & Integrat Sci, New Delhi 110067, India.
Bhattacherjee, A (corresponding author), Heidelberg Univ, Inst Theoret Phys, Heidelberg, Germany. |
|
E-mail Addresses:
arnab@jnu.ac.in |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; Ruprecht Karls University Heidelberg |
|
Publisher:
ELSEVIER
|
|
Publisher Address:
RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Biochemistry & Molecular Biology; Biophysics |
|
Research Areas:
Biochemistry & Molecular Biology; Biophysics |
|
IDS Number:
SC4F9
|
|
ISSN:
1874-9399
|
|
eISSN:
1876-4320
|
|
29-char Source Abbrev.:
BBA-GENE REGUL MECH
|
|
ISO Source Abbrev.:
Biochim. Biophys. Acta-Gene Regul. Mech.
|
|
Source Item Page Count:
8
|
| Funding: |
| Funding Agency | Grant Number |
|
DST India |
CRG/2023/000636
|
|
DBT India |
BT/PR46247/BID/7/1015/2023
|
|
DBT CoE research grant | |
|
Alexandar von Humboldt Foundation, Germany | |
|
Ministry of Human Resource Development (MHRD), Govt. of India |
PMRF-192002-617
|
|
|
We gratefully acknowledge the financial support from DST India (CRG/2023/000636) , DBT India (BT/PR46247/BID/7/1015/2023) and DBT CoE research grant. A.B. gratefully acknowledges support from the Alexandar von Humboldt Foundation, Germany. Sangeeta acknowledges the financial support from the Ministry of Human Resource Development (MHRD) , Govt. of India for Prime Minister’s Research Fellowship (PMRF-192002-617) . We thank Prof. Devapriya Choudhury, JNU and Prof. Narinder Singh Sahni, JNU for valuable scientific discussions and suggestions related to the statistical analysis of the manuscript.
|
|
Output Date:
2024-07-01
|
| Record 22 of 44 |
|
Title:
Crosstalk between lattice-spin electron dynamics at spin textures and across multiple magnetic-electronic phases in La 1-<i> x</i> Sr<i> x</i> MnO 3 (<i> x</i>=0 . 125, 0.175)
|
|
Author(s):
Mekap, S (Mekap, Smrutiranjan); Tiwari, JK (Tiwari, Jeetendra Kumar); Baro, A (Baro, Ajay); Das, T (Das, Tilak); Ghosh, S (Ghosh, Subhasis); Roy, A (Roy, Anushree) |
| Source:
PHYSICAL REVIEW B Volume:
109 Issue:
21 Article Number:
214411 DOI:
10.1103/PhysRevB.109.214411 Published Date:
2024 JUN 7 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
2 |
|
Usage Count
(Since 2013):
2 |
|
Cited Reference Count:
80
|
|
Abstract:
Recently observed skyrmionic, bubble, stripelike spin textures, along with multiple possible magnetic and related electrical phases, have renewed interest in doped rare-earth perovskite material, lanthanum strontium manganite La 1 – x Sr x MnO 3 (LSMO). Microscopic mechanisms that lead to exotic spin dynamics, spin structures, and electrical transport of LSMO over the varied temperature range are still not well understood. In the present study, temperature -dependent micro -Raman spectroscopic measurements indicate the intriguing trend of the evolution of spin -phonon and electron -phonon couplings with temperature across multiple magnetic and electrical phases in LSMO ( x = 0 . 125, 0.175) having orthorhombic and rhombohedral phases. Electrical transport and magnetization studies revealed a metal -insulator phase transition in LSMO-0.125, whereas the system remains in the metallic phase in LSMO-0.175 over the low -temperature ferromagnetically ordered state. The observed anomalous Raman spectral shifts across magnetic phase transition temperatures relate to the complex nature of the coupling between spin and phonon dynamics in these compounds. Especially, the systematic modulation in the change in Raman shift with temperature in the ferromagnetic metallic phase, over which these materials are expected to exhibit nearly zero -field stripe spin structure, is noteworthy. The onset of such a trend is observed just above the paramagnetic -to -ferromagnetic phase transition temperature in LSMO-0.125. The unusual variation of Raman spectral linewidth at the crossover between the insulating and metallic ferromagnetic phase in LSMO-0.125 indicates an intertwined electron density of states near Fermi energy and phonon dynamics at this juncture. To this end, we report the expected signature of the existence of orbital polaron in the ferromagnetic insulating phase of LSMO-0.125 by studying the detailed spectral profiles of high wave -number Raman modes under different excitation wavelengths and varying temperatures. Combined manifold spin -phonon coupling schemes and the existence of orbital polaron in the ferromagnetic insulating phase, as could be qualitatively deliberated from Raman measurements, offer a crucial ingredient for a better understanding of microscopic mechanisms for the formation of exotic phases and various spin textures in LSMO. |
|
Accession Number:
WOS:001242983500002
|
|
Language:
English |
|
Document Type:
Article |
|
KeyWords Plus:
GIANT MAGNETORESISTANCE; TRANSITION; MANGANITE; POLARONS; PHONONS; OXIDES; STATE |
Addresses:
[Mekap, Smrutiranjan; Das, Tilak; Roy, Anushree] Indian Inst Technol Kharagpur, Dept Phys, Kharagpur 721302, India.
[Tiwari, Jeetendra Kumar; Baro, Ajay; Ghosh, Subhasis] Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India. |
|
Corresponding Address:
Mekap, S (corresponding author), Indian Inst Technol Kharagpur, Dept Phys, Kharagpur 721302, India. |
|
Affiliations:
Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) – Kharagpur; Jawaharlal Nehru University, New Delhi |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Ghosh, Subhasis | | 0000-0003-1346-5635 |
|
Das, Tilak | | 0000-0002-9593-7888 |
|
|
Publisher:
AMER PHYSICAL SOC
|
|
Publisher Address:
ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter |
|
Research Areas:
Materials Science; Physics |
|
IDS Number:
TR4W2
|
|
ISSN:
2469-9950
|
|
eISSN:
2469-9969
|
|
29-char Source Abbrev.:
PHYS REV B
|
|
ISO Source Abbrev.:
Phys. Rev. B
|
|
Source Item Page Count:
12
|
| Funding: |
| Funding Agency | Grant Number |
|
CRG by SERB, India |
CRG/2021/000718
|
|
Science and Engineering Research Board (SERB) , Government of India |
RJF/2021/000120
|
|
Ministry of Electronics and Information Technology (MeitY) | |
|
Department of Science and Technology (DST) , Government of India | |
|
SERB, Department of Science and Technology, Government of India |
CRG/2021/000776
|
|
|
A.R. thanks CRG by SERB, India (Grant No. CRG/2021/000718) for financial assistance. T.D. received the support of the Science and Engineering Research Board (SERB) , Government of India, File No. RJF/2021/000120 for a research grant for Ramanujan Fellow. T.D. and A.R. acknowledge the National Supercomputing Mission (NSM) for providing computing resources of “PARAM Shakti” at IIT Kharagpur, which is implemented by C-DAC and supported by the Ministry of Electronics and Information Technology (MeitY) and the Department of Science and Technology (DST) , Government of India. This project is partially supported by SERB, Department of Science and Technology, Government of India, through the project with SERB Sanction Order No. CRG/2021/000776.
|
|
Output Date:
2024-07-01
|
| Record 23 of 44 |
|
Title:
Facile Synthesis of Polypyrrole/Reduced Graphene Oxide Composites for High-Performance Supercapacitor Applications
|
|
Author(s):
Saini, R (Saini, Rashmi); Singh, P (Singh, Paramjit); Kumar, R (Kumar, Rajesh); Kulriya, P (Kulriya, Pawan); Kumar, S (Kumar, Shalendra) |
| Source:
JOURNAL OF ELECTRONIC MATERIALS DOI:
10.1007/s11664-024-11207-5 Early Access Date:
JUN 2024 Published Date:
2024 JUN 11 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
44
|
|
Abstract:
Supercapacitors have drawn a lot of interest as energy storage devices because of their high-power density, quick charge/discharge rates, and long cycle life. However, the creation of cutting-edge electrode materials is essential in order to further improve their performance. Nanostructures made of graphene-based conducting polymers have shown promise because they combine the special qualities of both graphene and conducting polymers. In the present research, we synthesized the composites of reduced graphene oxide and polypyrrole conducting polymer by in situ chemical polymerization by varying their mass ratio. The fabricated samples were characterized by FTIR spectroscopy, Raman spectroscopy, TEM, XPS, XRD, and cyclic voltammetry for further analyses for these nanostructures’ potential application in energy storage devices. Composite fabrication was verified through FTIR and Raman spectroscopy by confirming distinct peaks. TEM studies confirmed the presence of thin and randomly aggregated graphene oxide nanoparticles. XPS survey spectra identified carbon, nitrogen, and oxygen, with major peaks at 284 eV, 399 eV, and 531 eV, reflecting variations in C, N, and O. Cyclic voltammetry determined specific capacitance values of 4.66 F/g and 6.11 F/g for different mass ratios of polypyrrole and reduced graphene oxide. |
|
Accession Number:
WOS:001244800000001
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
Conducting polymers; reduced graphene oxide; energy storage; supercapacitors |
|
KeyWords Plus:
OXIDE/POLYPYRROLE COMPOSITE; NANOCOMPOSITES; ELECTRODES |
Addresses:
[Saini, Rashmi; Kumar, Rajesh] Guru Gobind Singh Indraprastha Univ, Univ Sch Basic & Appl Sci, New Delhi 110078, India.
[Singh, Paramjit] Gujranwala Guru Nanak Khalsa Coll, Dept Phys, Ludhiana 141001, Punjab, India.
[Kulriya, Pawan] Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India.
[Kumar, Shalendra] Univ Petr & Energy Studies, Dept Phys, Dehra Dun 248007, India. |
|
Corresponding Address:
Singh, P (corresponding author), Gujranwala Guru Nanak Khalsa Coll, Dept Phys, Ludhiana 141001, Punjab, India. |
|
E-mail Addresses:
psd1985@gmail.com |
|
Affiliations:
GGS Indraprastha University; Jawaharlal Nehru University, New Delhi; University of Petroleum & Energy Studies (UPES) |
|
Publisher:
SPRINGER
|
|
Publisher Address:
ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Engineering, Electrical & Electronic; Materials Science, Multidisciplinary; Physics, Applied |
|
Research Areas:
Engineering; Materials Science; Physics |
|
IDS Number:
TY4G1
|
|
ISSN:
0361-5235
|
|
eISSN:
1543-186X
|
|
29-char Source Abbrev.:
J ELECTRON MATER
|
|
ISO Source Abbrev.:
J. Electron. Mater.
|
|
Source Item Page Count:
10
|
| Funding: |
| Funding Agency | Grant Number |
|
Science and Engineering Research Board (SERB), Department of Science and Technology, Government of India |
TAR/2021/000128
|
|
Malaviya National Institute of Technology (MNIT), Jaipur, India | |
|
Guru Gobind Indraprastha University, New Delhi, India | |
|
|
One of the authors Dr. Paramjit Singh is highly thankful to Science and Engineering Research Board (SERB), Department of Science and Technology, Government of India for providing financial assistance under Teachers Associateship for Research Excellence (TARE) Research Project (File No. TAR/2021/000128) to carry-out this research work. The characterization facilities provided by Malaviya National Institute of Technology (MNIT), Jaipur, India are gratefully acknowledged. The author Miss Rashmi Saini is thankful to Guru Gobind Indraprastha University, New Delhi, India for providing Short Term Research Fellowship (STRF).
|
|
Output Date:
2024-07-01
|
| Record 24 of 44 |
|
Title:
Influence of growth temperature on the magnetization dynamics of sputtered CoFeB thin films on various substrates and their microwave device functionality
|
|
Author(s):
Kumar, P (Kumar, Prashant); Kumar, R (Kumar, Ravi); Sharma, V (Sharma, Vipul); Khanna, MK (Khanna, Manoj Kumar); Kuanr, BK (Kuanr, Bijoy Kumar) |
| Source:
JOURNAL OF ALLOYS AND COMPOUNDS Volume:
988 Article Number:
174314 DOI:
10.1016/j.jallcom.2024.174314 Published Date:
2024 JUN 15 |
|
Times Cited in Web of Science Core Collection:
1
|
|
Total Times Cited:
1
|
|
Usage Count
(Last 180 days):
4 |
|
Usage Count
(Since 2013):
4 |
|
Cited Reference Count:
56
|
|
Abstract:
In the present investigation, sputtering growth of 100 nm thick Co40Fe40B20 (CoFeB) film has been investigated in a low temperature range from room temperature (RT) to 400 degrees C on silicon (Si), silicon dioxide (Si/SiO2), and sapphire (Al2O3) substrates. The film surface morphology, static and dynamic magnetization were measured as a function of growth temperature and substrate. The grown films were further tested as a potential material for microwave device functionality in terms of filter and phase shifter. Surface roughness was lowest for the film grown on Si/SiO2 substrate at 200 degrees C (0.39 nm) measured from atomic force microscopy. Static magnetic properties measured by tracing magnetic hysteresis loop suggest a soft magnetic behaviour with in-plane magnetic anisotropy. Film saturation magnetization increases with the increase in growth temperature up to 200 degrees C and then decreases from 200 degrees C to 400 degrees C. This suggest that the sputtering growth from room temperature to 200 degrees C offer a moderate to low interfacial stress resulting in low defects density. Gilbert damping constant (alpha eff) of the thin film is obtained from the ferromagnetic resonance measurements in a broad band of microwave frequencies. Damping was lowest (5.4×10- 3) in the film grown at 200 degrees C on the Si/SiO2 substrate which correlates with the roughness and magnetization data. A low value of alpha eff is desirable for a material to be used in energy efficient spintronics and magnonic applications. The CoFeB films were also utilized in prototype microwave band-stop filter and phase shifter device applications. The filter has been tested in the frequency range from 6GHz to 25GHz with an applied magnetic bias up to 4.0 kOe. The frequency tunability with respect to the applied magnetic bias measured to be around 3.64 GHz/kOe. The maximum attenuation of -4dB was observed for the film grown on Si/SiO2 substrate at 200 degrees C. Whereas, phase shifter fabricated on Si/SiO2/CoFeB film grown at 200 degrees C shows a differential phase shift up to 75 degrees/cm. These results indicates that the CoFeB film deposited at low growth temperature can be a potential material in spintronics and CMOS applications where low temperatures are required for device fabrications. |
|
Accession Number:
WOS:001219486600001
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
CoFeB film; Magnetization dynamics; Gilbert damping; Microwave device; Band -stop filter; Phase shifter |
|
KeyWords Plus:
DEPOSITION; ANISOTROPY; THICKNESS |
Addresses:
[Kumar, Prashant; Khanna, Manoj Kumar] Univ Delhi, Dept Elect Sci, New Delhi 110021, India.
[Kumar, Prashant; Kuanr, Bijoy Kumar] Jawaharlal Nehru Univ, Special Ctr Nanosci, New Delhi 110067, India.
[Kumar, Prashant] Univ Delhi, Motilal Nehru Coll, Delhi 110021, India.
[Kumar, Ravi] Univ Delhi, Shaheed Rajguru Coll Appl Sci Women, New Delhi 110096, India.
[Sharma, Vipul] Northeastern Univ, Dept Phys, Boston, MA 02115 USA. |
Corresponding Address:
Khanna, MK (corresponding author), Univ Delhi, Dept Elect Sci, New Delhi 110021, India.
Kuanr, BK (corresponding author), Jawaharlal Nehru Univ, Special Ctr Nanosci, New Delhi 110067, India. |
|
E-mail Addresses:
dr_manojkhanna@yahoo.co.in; bkkuanr@gmail.com |
|
Affiliations:
University of Delhi; Jawaharlal Nehru University, New Delhi; University of Delhi; University of Delhi; Northeastern University |
|
Publisher:
ELSEVIER SCIENCE SA
|
|
Publisher Address:
PO BOX 564, 1001 LAUSANNE, SWITZERLAND
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Chemistry, Physical; Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering |
|
Research Areas:
Chemistry; Materials Science; Metallurgy & Metallurgical Engineering |
|
IDS Number:
QF5W5
|
|
ISSN:
0925-8388
|
|
eISSN:
1873-4669
|
|
29-char Source Abbrev.:
J ALLOY COMPD
|
|
ISO Source Abbrev.:
J. Alloy. Compd.
|
|
Source Item Page Count:
9
|
| Funding: |
| Funding Agency | Grant Number |
|
Science and Engineering Research Board |
EMR/2017/003351
|
|
DST AMT Government of India | |
|
|
The authors in the manuscript thank AIRF JNU for the PPMS. BKK acknowledge the Financial Grant support from Science and Engineering Research Board (EMR/2017/003351) , and DST AMT Government of India. Thin film deposition, XRD, AFM and FMR measurements are performed at SCNS, JNU.
|
|
Output Date:
2024-07-01
|
| Record 25 of 44 |
|
Title:
A one-pot ultrasound-assisted regio and stereoselective synthesis of indenoquinoxaline engrafted spiropyrrolidines
|
|
Author(s):
Bokam, R (Bokam, Ramesh); Munipalle, K (Munipalle, Kiran); Annam, SCVAR (Annam, S. Ch. V. Appa Rao); Gundoju, N (Gundoju, Narayanarao); Chowhan, LR (Chowhan, L. Raju); Ponnapalli, MG (Ponnapalli, Mangala Gowri) |
| Source:
ORGANIC & BIOMOLECULAR CHEMISTRY DOI:
10.1039/d4ob00288a Early Access Date:
JUN 2024 Published Date:
2024 JUN 10 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
29
|
Abstract:
A catalyst free ultrasound-assisted regio-/stereoselective modular approach was accomplished for the synthesis of highly constrained indenoquinoxaline engrafted spiro pyrrolidines from easily available substrates. This one-pot strategy utilizes 1,3-dipolar cycloaddition from a four component reaction of ninhydrin, 1,2-phenylenediamine, beta-nitrostyrene and benzylamine or amino acids under ultrasound irradiation. The transformation is mild and operationally simple, providing architecturally complex fused spiro polycyclic heterocycles. This synthesis was confined to follow the group-assistant-purification (GAP) chemistry process, which can avoid chromatographic purifications and use of catalysts and allows easy access to a novel class of spiro engrafted polyheterocyclic scaffolds, which may be beneficial in biomedical research/materials science in the near future. This opens an era for the formation of a single exo product, when compared with reported protocols, by merely switching over reaction conditions to US irradiation.
We have demonstrated a catalyst free ultrasound-assisted multicomponent synthesis of highly regio and stereoselective spiropyrrolidines containing the indenoquinoxaline moiety via a 1,3-dipolar cycloaddition strategy. |
|
Accession Number:
WOS:001242609900001
|
|
PubMed ID:
38856015
|
|
Language:
English |
|
Document Type:
Article; Early Access |
Addresses:
[Bokam, Ramesh; Munipalle, Kiran; Annam, S. Ch. V. Appa Rao; Gundoju, Narayanarao; Ponnapalli, Mangala Gowri] CSIR Indian Inst Chem Technol, Dept Nat Prod & Med Chem, Hyderabad 500007, India.
[Munipalle, Kiran; Ponnapalli, Mangala Gowri] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India.
[Chowhan, L. Raju] Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India. |
Corresponding Address:
Ponnapalli, MG (corresponding author), CSIR Indian Inst Chem Technol, Dept Nat Prod & Med Chem, Hyderabad 500007, India.
Ponnapalli, MG (corresponding author), Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India. |
|
E-mail Addresses:
mangala.iict@gov.in |
|
Affiliations:
Council of Scientific & Industrial Research (CSIR) – India; CSIR – Indian Institute of Chemical Technology (IICT); Academy of Scientific & Innovative Research (AcSIR); Jawaharlal Nehru University, New Delhi |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Chowhan, Dr. L Raju | S-4302-2018 | 0000-0002-5434-4488 |
|
|
Publisher:
ROYAL SOC CHEMISTRY
|
|
Publisher Address:
THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Chemistry, Organic |
|
Research Areas:
Chemistry |
|
IDS Number:
TQ0P0
|
|
ISSN:
1477-0520
|
|
eISSN:
1477-0539
|
|
29-char Source Abbrev.:
ORG BIOMOL CHEM
|
|
ISO Source Abbrev.:
Org. Biomol. Chem.
|
|
Source Item Page Count:
9
|
| Funding: |
| Funding Agency | Grant Number |
|
University Grants Commission | |
|
University Grants Commission/Council of Scientific and Industrial Research, New Delhi | |
|
|
B. R., K. M., N. G. and S. Ch. V. A. R. A. are thankful to the University Grants Commission/Council of Scientific and Industrial Research, New Delhi for the research fellowship. We thank NMR group, CSIR-IICT for providing 2D NMR data and JNU for SCXRD facility. [CSIR-IICT Communication No. IICT/Pubs./2024/100].
|
|
Output Date:
2024-07-01
|
| Record 26 of 44 |
|
Title:
Identification of Small Molecule Inhibitors Targeting Phosphoserine Phosphatase: A Novel Target for the Development of Antiamoebic Drugs
|
|
Author(s):
Kumari, P (Kumari, Poonam); Agrawal, P (Agrawal, Prakhar); Umarao, P (Umarao, Preeti); Ramachandran, V (Ramachandran, Vijayan); Gourinath, S (Gourinath, Samudrala) |
| Source:
ACS OMEGA DOI:
10.1021/acsomega.3c09439 Early Access Date:
JUN 2024 Published Date:
2024 JUN 17 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
80
|
|
Abstract:
Amoebiasis, a widespread disease caused by the protozoan parasite Entamoeba histolytica, poses challenges due to the adverse effects of existing antiamoebic drugs and rising drug resistance. Novel targeted drugs are in need of the hour to combat the prevalence of this disease. Given the significance of cysteine for Entamoeba survival, the rate-determining step in the serine (the sole substrate of cysteine synthesis) biosynthetic pathway, i.e., the conversion of 3-phosphoserine to l-serine catalyzed by phosphoserine phosphatase (PSP), emerges as a promising drug target. Our previous study unveils the essential role of EhPSP in amoebas’ survival, particularly under oxidative stress, by increasing cysteine production. The study also revealed that EhPSP differs significantly from its human counterpart, both structurally and biochemically, highlighting its potential as a viable target for developing new antiamoebic drugs. In the present study, employing in silico screening of vast natural and synthetic small chemical compound libraries, we identified 21 potential EhPSP inhibitor molecules. Out of the 21 compounds examined, only five could inhibit the catalytic activity of EhPSP. The inhibition capability of these five compounds was subsequently validated by in silico binding free energy calculations, SPR-based real-time binding studies, and molecular simulations to assess the stability of the EhPSP-inhibitor complexes. By identifying the five potential inhibitors that can target cysteine synthesis via EhPSP, our findings establish EhPSP as a drug candidate that can serve as a foundation for antiamoebic drug research. |
|
Accession Number:
WOS:001249661000001
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
KeyWords Plus:
D-PHOSPHOGLYCERATE DEHYDROGENASE; ENTAMOEBA-HISTOLYTICA; SUPEROXIDE-DISMUTASE; PROTOZOAN PARASITE; CYSTEINE SYNTHASE; METRONIDAZOLE RESISTANCE; NITROIMIDAZOLE DRUGS; PROTEIN; METABOLISM; MECHANISMS |
Addresses:
[Kumari, Poonam; Agrawal, Prakhar] Int Ctr Genet Engn & Biotechnol, New Delhi 110067, India.
[Kumari, Poonam; Umarao, Preeti; Gourinath, Samudrala] Jawaharlal Nehru Univ, Sch Life Sci, Struct Biol Lab, New Delhi 110067, India.
[Ramachandran, Vijayan] Univ Arizona, Ctr Innovat Brain Sci, Tucson, AZ 85721 USA. |
Corresponding Address:
Kumari, P (corresponding author), Int Ctr Genet Engn & Biotechnol, New Delhi 110067, India.
Kumari, P; Gourinath, S (corresponding author), Jawaharlal Nehru Univ, Sch Life Sci, Struct Biol Lab, New Delhi 110067, India. |
|
E-mail Addresses:
sgourinath@mail.jnu.ac.in; poonam.bio12@yahoo.co.in |
|
Affiliations:
Department of Biotechnology (DBT) India; International Center for Genetic Engineering & Biotechnology (ICGEB); International Center for Genetic Engineering & Biotechnology (ICGEB), New Delhi; Jawaharlal Nehru University, New Delhi; University of Arizona |
|
Publisher:
AMER CHEMICAL SOC
|
|
Publisher Address:
1155 16TH ST, NW, WASHINGTON, DC 20036 USA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Chemistry, Multidisciplinary |
|
Research Areas:
Chemistry |
|
IDS Number:
UR0G0
|
|
ISSN:
2470-1343
|
|
29-char Source Abbrev.:
ACS OMEGA
|
|
ISO Source Abbrev.:
ACS Omega
|
|
Source Item Page Count:
13
|
| Funding: |
| Funding Agency | Grant Number |
|
Department of Biotechnology, Ministry of Science and Technology, India | |
|
ICMR-SRF, India | |
|
|
S.G. is thankful for the SERB-STAR grant. P.K. and P.U. thank the DBT-MK BHAN Postdoctoral Fellowship and ICMR-SRF, India, respectively, for providing them with their fellowships.
|
|
Open Access:
gold
|
|
Output Date:
2024-07-01
|
| Record 27 of 44 |
|
Title:
Genome-wide mapping of DNase I hypersensitive sites revealed differential chromatin accessibility and regulatory DNA elements under drought stress in rice cultivars
|
|
Author(s):
Rajkumar, MS (Rajkumar, Mohan Singh); Tembhare, K (Tembhare, Kunal); Garg, R (Garg, Rohini); Jain, M (Jain, Mukesh) |
| Source:
PLANT JOURNAL DOI:
10.1111/tpj.16864 Early Access Date:
JUN 2024 Published Date:
2024 JUN 10 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
91
|
|
Abstract:
Drought stress (DS) is one of the major constraints limiting yield in crop plants including rice. Gene regulation under DS is largely governed by accessibility of the transcription factors (TFs) to their cognate cis-regulatory elements (CREs). In this study, we used DNase I hypersensitive assays followed by sequencing to identify the accessible chromatin regions under DS in a drought-sensitive (IR64) and a drought-tolerant (N22) rice cultivar. Our results indicated that DNase I hypersensitive sites (DHSs) were highly enriched at transcription start sites (TSSs) and numerous DHSs were detected in the promoter regions. DHSs were concurrent with epigenetic marks and the genes harboring DHSs in their TSS and promoter regions were highly expressed. In addition, DS induced changes in DHSs (triangle DHSs) in TSS and promoter regions were positively correlated with upregulation of several genes involved in drought/abiotic stress response, those encoding TFs and located within drought-associated quantitative trait loci, much preferentially in the drought-tolerant cultivar. The CREs representing the binding sites of TFs involved in DS response were detected within the triangle DHSs, suggesting differential accessibility of TFs to their cognate sites under DS in different rice cultivars, which may be further deployed for enhancing drought tolerance in rice. |
|
Accession Number:
WOS:001243487600001
|
|
PubMed ID:
38859561
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
DNase I; rice; cis-regulatory elements; epigenetic modifications; gene expression and drought stress |
|
KeyWords Plus:
TRANSCRIPTION FACTORS; ABIOTIC STRESS; OSMOTIC-STRESS; ABSCISIC-ACID; GRAIN-YIELD; TOLERANCE; GENE; METHYLATION; RESPONSES; FAMILY |
Addresses:
[Rajkumar, Mohan Singh; Tembhare, Kunal; Jain, Mukesh] Jawaharlal Nehru Univ, Sch Computat & Integrat Sci, New Delhi 110067, India.
[Garg, Rohini] Shiv Nadar Univ, Sch Nat Sci, Dept Life Sci, Gautam Buddha Nagar 201314, Uttar Pradesh, India.
[Rajkumar, Mohan Singh] Texas A&M AgriLife Res & Extens Ctr, Weslaco, TX USA. |
|
Corresponding Address:
Jain, M (corresponding author), Jawaharlal Nehru Univ, Sch Computat & Integrat Sci, New Delhi 110067, India. |
|
E-mail Addresses:
mjain@jnu.ac.in |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; Shiv Nadar University; Texas A&M University System; Texas A&M University College Station; Texas A&M AgriLife Research |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Jain, Mukesh | | 0000-0002-7622-1083 |
|
|
Publisher:
WILEY
|
|
Publisher Address:
111 RIVER ST, HOBOKEN 07030-5774, NJ USA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Plant Sciences |
|
Research Areas:
Plant Sciences |
|
IDS Number:
TT4D6
|
|
ISSN:
0960-7412
|
|
eISSN:
1365-313X
|
|
29-char Source Abbrev.:
PLANT J
|
|
ISO Source Abbrev.:
Plant J.
|
|
Source Item Page Count:
17
|
| Funding: |
| Funding Agency | Grant Number |
|
Department of Biotechnology, Ministry of Science and Technology, India |
CRG/2020/000172
|
|
Science and Engineering Research Board, New Delhi |
BT/PR40261/BTIS/137/55/2023
|
|
Department of Biotechnology, Government of India, under the National Network Project | |
|
TATA Innovation Fellowship scheme | |
|
Department of Science and Technology, Government of India | |
|
Department of Biotechnology, Government of India | |
|
|
This work was financially sponsored by the Science and Engineering Research Board, New Delhi (CRG/2020/000172). The financial support provided by the Department of Biotechnology, Government of India, under the National Network Project (BT/PR40261/BTIS/137/55/2023) and TATA Innovation Fellowship scheme is also gratefully acknowledged. The support from Department of Science and Technology, Government of India, under the Fund for Improvement of S&T infrastructure in universities and higher educational institutions (FIST) scheme at JNU is acknowledged. MSR acknowledges the Department of Biotechnology, Government of India, for Research Associateship. We are thankful to Dr. Somya Sinha for help with initial DNase-seq sample preparation.
|
|
Output Date:
2024-07-01
|
| Record 28 of 44 |
|
Title:
Production of fatty acids from distilled aromatic waste biomass using oleaginous yeast
|
|
Author(s):
Singh, S (Singh, Suman); Chaturvedi, S (Chaturvedi, Shivani); Syed, N (Syed, Naziya); Rastogi, D (Rastogi, Dheerendra); Kumar, P (Kumar, Prashant); Sharma, PK (Sharma, Praveen Kumar); Kumar, D (Kumar, Deepak); Sahoo, D (Sahoo, Debesmita); Srivastava, N (Srivastava, Nitin); Nannaware, AD (Nannaware, Ashween Deepak); Khare, SK (Khare, Sunil Kumar); Rout, PK (Rout, Prasant Kumar) |
| Source:
BIOMASS & BIOENERGY Volume:
185 Article Number:
107213 DOI:
10.1016/j.biombioe.2024.107213 Published Date:
2024 JUN |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
43
|
|
Abstract:
Microbial lipids are feasible alternatives to vegetable oils and fats in the production of biodiesel and other industrially significant compounds. To achieve the main goals of the circular economy, waste materials go under microbiological processes, it reduces wastes through recycling. To show the effectiveness of the suggested strategy, four fungi, and four oleaginous yeasts were used in the present investigation. Along with this, distilled biomasses from different aromatic crops (lemongrass, mentha, citronella, geranium, ocimum, palmarosa) were used for microbial growth and lipid production. The distillation process acts as a pretreatment step for the fermentation of lignocellulosic biomass. The heat results in the breakdown of some bonds to easily release monomers and increase the available surface for the action of hydrolytic enzymes produced by fermenting microbes to release monomers which may be used further for lipid production. The lipid content obtained by Trichoderma harzianum, Rhodotorula glutinosa, Rhodotorula mucilaginosa, Aspergillus awamori, and Fusarium solani under optimized growth conditions were found significant in comparison to other strains, control 1 and 2. Lemongrass, citronella, ocimum, and palmarosa showed a promising lipid accumulation in comparison to other distilled biomasses. The major fatty acids produced by Rhodotorula glutinosa, R. mucilaginosa, Trichosporon cutaneous, Aspergillus awamori and Trichoderma harzianum were oleic, linoleic, linolenic and lignoceric acid from after distilled biomass of mentha, citronella and ocimum. Principal component analysis was performed to observe the variability within the dataset and provide evidence that the results are matching with the observations. Scanning electron microscopy and confocal fluorescence microscopy were also performed to confirm the lipid production by R. mucilaginosa and Aspergillus awamori . The oil obtained from R. mucilaginosa was further transesterified and assessed for their physical properties as biodiesel. It is found suitable to be used as bio-based fuel with the EN 14214 as well as ASTM D6751 standards. As a result, the distilled biomasses will provide a lowcost alternative for yeast growth that leads to accumulation of lipids and subsequently biodiesel generation. In order to integrate biotechnological processes in a circular economy challenge, this study offers convincing evidence that the valorization of distilled biomasses to lipid production using oleaginous yeasts is promising. |
|
Accession Number:
WOS:001233142600001
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Microbial lipids; Oleaginous yeasts; Distilled biomass; Biodiesel |
|
KeyWords Plus:
LIPID PRODUCTION; BIODIESEL; OIL |
Addresses:
[Singh, Suman; Chaturvedi, Shivani; Syed, Naziya; Rastogi, Dheerendra; Kumar, Prashant; Sharma, Praveen Kumar; Kumar, Deepak; Sahoo, Debesmita; Nannaware, Ashween Deepak; Rout, Prasant Kumar] CSIR Cent Inst Med & Aromat Plants, Phytochem Div, Lucknow 226015, Uttar Pradesh, India.
[Srivastava, Nitin; Khare, Sunil Kumar] Indian Inst Technol, Dept Chem, Enzyme & Microbial Biochem Lab, New Delhi 110016, India.
[Syed, Naziya] Jawaharlal Nehru Univ, New Delhi 110067, India. |
|
Corresponding Address:
Chaturvedi, S (corresponding author), CSIR Cent Inst Med & Aromat Plants, Phytochem Div, Lucknow 226015, Uttar Pradesh, India. |
|
E-mail Addresses:
shivani.d123@gmail.com |
|
Affiliations:
Council of Scientific & Industrial Research (CSIR) – India; CSIR – Central Institute of Medicinal & Aromatic Plants (CIMAP); Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) – Delhi; Jawaharlal Nehru University, New Delhi |
|
Publisher:
PERGAMON-ELSEVIER SCIENCE LTD
|
|
Publisher Address:
THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Agricultural Engineering; Biotechnology & Applied Microbiology; Energy & Fuels |
|
Research Areas:
Agriculture; Biotechnology & Applied Microbiology; Energy & Fuels |
|
IDS Number:
SF8V8
|
|
ISSN:
0961-9534
|
|
eISSN:
1873-2909
|
|
29-char Source Abbrev.:
BIOMASS BIOENERG
|
|
ISO Source Abbrev.:
Biomass Bioenerg.
|
|
Source Item Page Count:
12
|
| Funding: |
| Funding Agency | Grant Number |
|
DST |
DST/WOS-A/CS-94/2021
|
|
|
Authors are grateful to the Dr. Prabodh K. Trivedi, Director, CSIR- CIMAP Lucknow for facilitating the work and his constant encourage- ment. Dr. S Chaturvedi is thankful to DST for Women Scientist fellow- ship (DST/WOS-A/CS-94/2021) .
|
|
Output Date:
2024-07-01
|
| Record 29 of 44 |
|
Title:
Surgical Tumor Resection Deregulates Hallmarks of Cancer in Resected Tissue and the Surrounding Microenvironment
|
|
Author(s):
Chaubal, R (Chaubal, Rohan); Gardi, N (Gardi, Nilesh); Joshi, S (Joshi, Shalaka); Pantvaidya, G (Pantvaidya, Gouri); Kadam, R (Kadam, Rasika); Vanmali, V (Vanmali, Vaibhav); Hawaldar, R (Hawaldar, Rohini); Talker, E (Talker, Elizabeth); Chitra, J (Chitra, Jaya); Gera, P (Gera, Poonam); Bhatia, D (Bhatia, Dimple); Kalkar, P (Kalkar, Prajakta); Gurav, M (Gurav, Mamta); Shetty, O (Shetty, Omshree); Desai, S (Desai, Sangeeta); Krishnan, NM (Krishnan, Neeraja M.); Nair, N (Nair, Nita); Parmar, V (Parmar, Vani); Dutt, A (Dutt, Amit); Panda, B (Panda, Binay); Gupta, S (Gupta, Sudeep); Badwe, R (Badwe, Rajendra) |
| Source:
MOLECULAR CANCER RESEARCH Volume:
22 Issue:
6 Pages:
572-584 DOI:
10.1158/1541-7786.MCR-23-0265 Published Date:
2024 JUN 4 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
53
|
|
Abstract:
Surgery exposes tumor tissue to severe hypoxia and mechanical stress leading to rapid gene expression changes in the tumor and its microenvironment, which remain poorly characterized. We biopsied tumor and adjacent normal tissues from patients with breast (n = 81) and head/neck squamous cancers (HNSC; n = 10) at the beginning (A), during (B), and end of surgery (C). Tumor/normal RNA from 46/81 patients with breast cancer was subjected to mRNA-Seq using Illumina short-read technology, and from nine patients with HNSC to whole-transcriptome microarray with Illumina BeadArray. Pathways and genes involved in 7 of 10 known cancer hallmarks, namely, tumor-promoting inflammation (TNF-A, NFK-B, IL18 pathways), activation of invasion and migration (various extracellular matrix-related pathways, cell migration), sustained proliferative signaling (K-Ras Signaling), evasion of growth suppressors (P53 signaling, regulation of cell death), deregulating cellular energetics (response to lipid, secreted factors, and adipogenesis), inducing angiogenesis (hypoxia signaling, myogenesis), and avoiding immune destruction (CTLA4 and PDL1) were significantly deregulated during surgical resection (time points A vs. B vs. C). These findings were validated using NanoString assays in independent pre/intra/post-operative breast cancer samples from 48 patients. In a comparison of gene expression data from biopsy (analogous to time point A) with surgical resection samples (analogous to time point C) from The Cancer Genome Atlas study, the top deregulated genes were the same as identified in our analysis, in five of the seven studied cancer types. This study suggests that surgical extirpation deregulates the hallmarks of cancer in primary tumors and adjacent normal tissue across different cancers.Implications: Surgery deregulates hallmarks of cancer in human tissue. |
|
Accession Number:
WOS:001239198100005
|
|
PubMed ID:
38394149
|
|
Language:
English |
|
Document Type:
Article |
|
KeyWords Plus:
FATTY-ACID SYNTHASE; METABOLISM; CHOLANGIOCARCINOMA; RISK; OBESITY; TARGET; FATP2; MICE |
Addresses:
[Chaubal, Rohan; Joshi, Shalaka; Pantvaidya, Gouri; Chitra, Jaya; Nair, Nita; Parmar, Vani; Badwe, Rajendra] Tata Mem Hosp, Tata Mem Ctr, Dept Surg Oncol, Mumbai, India.
[Chaubal, Rohan; Gardi, Nilesh; Joshi, Shalaka; Talker, Elizabeth; Chitra, Jaya; Bhatia, Dimple; Kalkar, Prajakta; Nair, Nita; Gupta, Sudeep; Badwe, Rajendra] Tata Mem Hosp, Adv Ctr Treatment Res & Educ Canc, Clinician Scientist Lab, Hypoxia & Clin Genom Lab, Navi Mumbai, Maharashtra, India.
[Chaubal, Rohan; Gardi, Nilesh; Joshi, Shalaka; Pantvaidya, Gouri; Kadam, Rasika; Vanmali, Vaibhav; Hawaldar, Rohini; Gurav, Mamta; Shetty, Omshree; Desai, Sangeeta; Nair, Nita; Parmar, Vani; Dutt, Amit; Gupta, Sudeep; Badwe, Rajendra] Homi Bhabha Natl Inst, Training Sch Complex, Mumbai, Maharashtra, India.
[Gardi, Nilesh; Kadam, Rasika; Talker, Elizabeth; Gupta, Sudeep] Tata Mem Hosp, Tata Mem Ctr, Dept Med Oncol, Mumbai, India.
[Vanmali, Vaibhav; Hawaldar, Rohini] Tata Mem Hosp, Tata Mem Ctr, Clin Res Secretariat, Mumbai, India.
[Gera, Poonam] Tata Mem Hosp, Adv Ctr Treatment Res & Educ Canc, Biorepository, Navi Mumbai, Maharashtra, India.
[Gurav, Mamta; Shetty, Omshree; Desai, Sangeeta] Tata Mem Hosp, Tata Mem Ctr, Dept Pathol, Mumbai, India.
[Krishnan, Neeraja M.; Panda, Binay] Jawaharlal Nehru Univ, Sch Biotechnol, New Delhi, India.
[Parmar, Vani] Tata Mem Hosp, Adv Ctr Treatment Res & Educ Canc, 3D Printing Lab, Navi Mumbai, Maharashtra, India.
[Dutt, Amit] Tata Mem Hosp, Adv Ctr Treatment Res & Educ Canc, Integrated Canc Genom Lab, Kharghar 410210, Navi Mumbai, India.
[Badwe, Rajendra] Tata Mem Hosp, Dr E Borges Rd, Mumbai 400012, Maharashtra, India. |
Corresponding Address:
Gupta, S; Badwe, R (corresponding author), Tata Mem Hosp, Adv Ctr Treatment Res & Educ Canc, Clinician Scientist Lab, Hypoxia & Clin Genom Lab, Navi Mumbai, Maharashtra, India.
Gupta, S; Badwe, R (corresponding author), Homi Bhabha Natl Inst, Training Sch Complex, Mumbai, Maharashtra, India.
Gupta, S (corresponding author), Tata Mem Hosp, Tata Mem Ctr, Dept Med Oncol, Mumbai, India.
Badwe, R (corresponding author), Tata Mem Hosp, Dr E Borges Rd, Mumbai 400012, Maharashtra, India. |
|
E-mail Addresses:
badwera@tmc.gov.in; sudeep.gupta@actrec.gov.in |
|
Affiliations:
Tata Memorial Centre (TMC); Tata Memorial Hospital; Tata Memorial Centre (TMC); Tata Memorial Hospital; Advance Centre for Treatment, Research & Education in Cancer (ACTREC); Homi Bhabha National Institute; Tata Memorial Centre (TMC); Tata Memorial Hospital; Tata Memorial Centre (TMC); Tata Memorial Hospital; Tata Memorial Centre (TMC); Tata Memorial Hospital; Advance Centre for Treatment, Research & Education in Cancer (ACTREC); Tata Memorial Centre (TMC); Tata Memorial Hospital; Jawaharlal Nehru University, New Delhi; Tata Memorial Centre (TMC); Tata Memorial Hospital; Advance Centre for Treatment, Research & Education in Cancer (ACTREC); Tata Memorial Centre (TMC); Tata Memorial Hospital; Advance Centre for Treatment, Research & Education in Cancer (ACTREC); Tata Memorial Centre (TMC); Tata Memorial Hospital |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Chaubal, Rohan | O-5062-2019 | 0000-0002-7226-8757 |
|
Joshi, Shalaka | | 0000-0003-3813-4680 |
|
Hawaldar, Rohini | | 0000-0002-3114-5689 |
|
Aadhi, Jaya chitra | | 0000-0002-8717-9490 |
|
|
Publisher:
AMER ASSOC CANCER RESEARCH
|
|
Publisher Address:
615 CHESTNUT ST, 17TH FLOOR, PHILADELPHIA, PA 19106-4404 USA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Oncology; Cell Biology |
|
Research Areas:
Oncology; Cell Biology |
|
IDS Number:
TD0F4
|
|
ISSN:
1541-7786
|
|
eISSN:
1557-3125
|
|
29-char Source Abbrev.:
MOL CANCER RES
|
|
ISO Source Abbrev.:
Mol. Cancer Res.
|
|
Source Item Page Count:
13
|
| Funding: |
| Funding Agency | Grant Number |
|
Department of Atomic Energy, Government of India (DAE) | |
|
Department of Atomic Energy, Government of India (GOI) | |
|
Women’s Cancer Initiative (WCI)-Tata Memorial Hospital – HBNI, Mumbai |
BT/MED/30/VNCI-Hr-BRCA/2015
|
|
TMC, Mumbai – Department of Biotechnology (DBT), GOI, through the DBT-Virtual National Cancer Institute (VNCI) Breast Cancer | |
|
Department of Science and Technology (DST)-Scientific Engineering and Research Board (SERB) Prime Minister’s Fellowship | |
|
|
This study was funded by the Department of Atomic Energy, Government of India (GOI). We acknowledge the generous support and funding received from Sunil Gupta for the NanoString nCounter Assays. We also acknowledge funding from Mizuho Bank Limited for research infrastructure at our institute. We are thankful to Akhil Gupta for funding laboratory infrastructure. We acknowledge part research funding for this study from the Women’s Cancer Initiative (WCI)-Tata Memorial Hospital. R. Chaubal and N. Gardi were funded by a fellowship from HBNI, Mumbai, and TMC, Mumbai. R. Chaubal, N. Gardi, and R. Kadam are also funded by a fellowship from the Department of Biotechnology (DBT), GOI, through the DBT-Virtual National Cancer Institute (VNCI) Breast Cancer 2015 grant (BT/MED/30/VNCI-Hr-BRCA/2015) awarded (to S. Gupta). N. Gardi is also funded by the Department of Science and Technology (DST)-Scientific Engineering and Research Board (SERB) Prime Minister’s Fellowship.
|
|
Open Access:
hybrid
|
|
Output Date:
2024-07-01
|
| Record 30 of 44 |
|
Title:
Investigations of thermal conductivity in nano-crystalline Gd<sub>2</sub>Ti<sub>2</sub>O<sub>7</sub> pyrochlore
|
|
Author(s):
Singh, Y (Singh, Yogendar); Kumar, V (Kumar, Vivek); Sharma, SK (Sharma, Saurabh Kumar); Vazhappilly, T (Vazhappilly, Tijo); Lian, J (Lian, Jie); Kulriya, PK (Kulriya, Pawan Kumar) |
| Source:
JOURNAL OF ALLOYS AND COMPOUNDS Volume:
990 Article Number:
174249 DOI:
10.1016/j.jallcom.2024.174249 Published Date:
2024 JUN 30 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
51
|
|
Abstract:
Pyrochlore ceramics with chemical formula A(2)B(2)O(7) (A= rare earth, B= tetravalent metal) have extremely low thermal conductivities (kappa) and are thought to be promising candidates for thermal barrier coatings (TBCs) applications. This study reports kappa for nanocrystalline (nc) Gd2Ti2O7 pyrochlore fabricated by spark plasma sintering followed by sintering at different temperatures to better understand their thermal properties. The structural analysis confirmed the synthesis of single-phase nc-Gd2Ti2O7 pyrochlore. The thermal conductivity investigations displayed a systematic decrease in thermal conductivity from 1.6 Wm(-1)K(-1) to 0.6 Wm(-1)K(-1) for the sample sintered at a lower temperature due to high porosity. The value of the kappa is found to decrease sublinearly (kappa proportional to T-alpha, where 0 < alpha < 1) with temperature for all the nc-Gd2Ti2O7 pyrochlore samples. DFT- GGA calculation exhibits that the nc-Gd2Ti2O7 is a direct band gap at the Gamma point of the Brillouin zone, and its value is increased with the sintering temperature. In addition, the effect of sintering temperature on the specific heat capacity (C-p) is insignificant in nc-Gd2Ti2O7 structures, as confirmed by the quasi-harmonic approximation. Theoretical and experimentally determined results are in good agreement, and values are compatible with the thermal insulation requirements for various applications. |
|
Accession Number:
WOS:001227321700001
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Nano-crystalline Ceramic; Spark Plasma Sintering; Thermal Conductivity; Pyrochlore |
|
KeyWords Plus:
THERMOPHYSICAL PROPERTIES; GRAIN-SIZE; TEMPERATURE; GROWTH |
Addresses:
[Singh, Yogendar; Kumar, Vivek; Kulriya, Pawan Kumar] Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India.
[Vazhappilly, Tijo] Bhabha Atom Res Ctr, Chem Div, Theoret Chem Sect, Mumbai 400085, India.
[Vazhappilly, Tijo] Homi Bhabha Natl Inst, Mumbai 400094, India.
[Sharma, Saurabh Kumar; Lian, Jie] Rensselaer Polytech Inst, Mech Aerosp & Nucl Engn Dept, Troy, NY 12180 USA. |
|
Corresponding Address:
Kulriya, PK (corresponding author), Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India. |
|
E-mail Addresses:
pkkulriya@mail.jnu.ac.in |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; Bhabha Atomic Research Center (BARC); Homi Bhabha National Institute; Rensselaer Polytechnic Institute |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Sharma, Dr. Saurabh Kumar | GYA-0495-2022 | 0000-0002-3520-9168 |
|
|
Publisher:
ELSEVIER SCIENCE SA
|
|
Publisher Address:
PO BOX 564, 1001 LAUSANNE, SWITZERLAND
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Chemistry, Physical; Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering |
|
Research Areas:
Chemistry; Materials Science; Metallurgy & Metallurgical Engineering |
|
IDS Number:
RJ5Y8
|
|
ISSN:
0925-8388
|
|
eISSN:
1873-4669
|
|
29-char Source Abbrev.:
J ALLOY COMPD
|
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ISO Source Abbrev.:
J. Alloy. Compd.
|
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Source Item Page Count:
9
|
| Funding: |
| Funding Agency | Grant Number |
|
United States-India Educational Foundation (USIF) |
251/FNPDR/2015
|
|
Board of Research in Nuclear Sciences (BRNS) |
58/14/05/2019-BRNS/37013
|
|
Ministry of Education, Govt. of India |
PMRF-2122-2836
|
|
|
One of the authors, Pawan Kumar Kulriya, acknowledges the United States-India Educational Foundation (USIF) for awarding a Fulbright Post Doctorate Fellowship (Award No. 251/FNPDR/2015) and the Board of Research in Nuclear Sciences (BRNS) for providing financial support under project 58/14/05/2019-BRNS/37013. Yogendar Singh acknowledges the Ministry of Education, Govt. of India, for awarding the Prime Minister’s Research Fellowship (PMRF) with reference number PMRF-2122-2836. The authors also acknowledge the Central Instrumentation Facility (CIF) and School of Physical Sciences (SPS) for XRD measurements. The authors acknowledge Mr. Saroj Jha for Raman spectroscopy measurements.
|
|
Output Date:
2024-07-01
|
| Record 31 of 44 |
|
Title:
Efficient electron transfer in CdSe quantum dots-decorated reduced graphene oxide for electromagnetic interference shielding application
|
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Author(s):
Yadav, AN (Yadav, Amar Nath); Upadhyay, S (Upadhyay, Shiva); Singh, AK (Singh, Ashwani Kumar); Singh, K (Singh, Kedar) |
| Source:
BULLETIN OF MATERIALS SCIENCE Volume:
47 Issue:
2 Article Number:
119 DOI:
10.1007/s12034-024-03240-1 Published Date:
2024 JUN 4 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
34
|
|
Abstract:
Effective charge separation and use of hot charge carriers are considered to be the most essential factors affecting the activity of an excellent energy harvester. Herein, we have successfully decorated 3 nm of CdSe quantum dots (QDs) on the surface of reduced graphene oxide (rGO) using solvothermal method. Formation of CdSe-rGO nanocomposite (NC) has been confirmed by X-ray diffraction pattern, transmission electron microscopy and Raman analysis. Further, the emission spectrum of CdSe-rGO NC shows quenching of emission of CdSe QDs on the surface of rGO nanosheet. To elucidate this phenomenon, we have carried out time-correlated single-photon counting (TCSPC) measurements, which reveal efficient electron transfer, as the exciton lifetime of CdSe QDs in the NC is significantly reduced compared to bare CdSe QDs. Owing to the efficient electron transfer, this NC showed big boost in total shielding effectiveness (SET = 29 dB) when compared to graphene (SET = 23 dB) in electromagnetic interference shielding application. |
|
Accession Number:
WOS:001239343200002
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Semiconductors; carbon materials; nanocomposites (NCs); spectroscopy |
|
KeyWords Plus:
SOLAR-CELLS; SEMICONDUCTOR; NANOCRYSTALS; NANOCOMPOSITE; NANOPARTICLES |
Addresses:
[Yadav, Amar Nath; Singh, Kedar] Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India.
[Upadhyay, Shiva] Univ Delhi, Swami Shraddhanand Coll, Dept Phys, Delhi 110036, India.
[Singh, Ashwani Kumar] Univ Delhi, Deshbandhu Coll, Dept Phys, Delhi 110019, India.
[Yadav, Amar Nath] Hanyang Univ, Div Mat Sci & Engn, Seoul 04763, South Korea. |
Corresponding Address:
Yadav, AN (corresponding author), Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India.
Yadav, AN (corresponding author), Hanyang Univ, Div Mat Sci & Engn, Seoul 04763, South Korea. |
|
E-mail Addresses:
amar22892@gmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; University of Delhi; University of Delhi; Hanyang University |
|
Publisher:
INDIAN ACAD SCIENCES
|
|
Publisher Address:
C V RAMAN AVENUE, SADASHIVANAGAR, P B #8005, BANGALORE 560 080, INDIA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Materials Science, Multidisciplinary |
|
Research Areas:
Materials Science |
|
IDS Number:
TD5T3
|
|
ISSN:
0250-4707
|
|
eISSN:
0973-7669
|
|
29-char Source Abbrev.:
B MATER SCI
|
|
ISO Source Abbrev.:
Bull. Mat. Sci.
|
|
Source Item Page Count:
8
|
| Funding: |
| Funding Agency | Grant Number |
|
SERB |
EEQ/2021/000097
|
|
Department of Science and Technology (DST)-SERB | |
|
University Grants Commission (UGC) | |
|
|
We thank AIRF, JNU, for providing the instrumentation facilities. KS gratefully acknowledges Department of Science and Technology (DST)-SERB, Govt. of India, for financial support under project no. EEQ/2021/000097. ANY acknowledges the University Grants Commission (UGC) for the JRF fellowship.
|
|
Output Date:
2024-07-01
|
| Record 32 of 44 |
|
Title:
Electrical and dielectric properties of optimized cubic structure with promising morphological texture in Ce<sub>0.8</sub>Zr<sub>0.2</sub>O<sub>2</sub>
|
|
Author(s):
Kumari, S (Kumari, Sushama); Sharma, SK (Sharma, Saurabh Kumar); Meena, R (Meena, Ramcharan); Atal, K (Atal, Krishna); Goel, VK (Goel, Vijay Kumar); Bugalia, S (Bugalia, Swati) |
| Source:
BULLETIN OF MATERIALS SCIENCE Volume:
47 Issue:
3 Article Number:
127 DOI:
10.1007/s12034-024-03244-x Published Date:
2024 JUN 13 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
37
|
|
Abstract:
Influence of structure and microstructure on the dielectric properties of single-phase solid solution of ZrO2-CeO2 system with 80% CeO2 has been investigated. Highly dense polycrystalline Ce0.8Zr0.2O2 ceramic was synthesized through solid-state reaction route, and its cubic structure was verified through X-ray diffraction and Raman spectroscopy techniques. The compact grain morphology was validated through FESEM with grain size of similar to 9 mu m. Dielectric properties of the Ce0.8Zr0.2O2 were probed by applying ac electric field of different frequencies at variable temperatures. The measured dielectric constant of Ce0.8Zr0.2O2 in the presence of applied ac field of 2 kHz frequency at 300 K is similar to 1819, is reduced to 27 with an increase in the frequency up to 2 MHz, which is a comparatively high dielectric constant than binary oxides. The high packing fraction of cubic structure of ZrO2-CeO2 with 80% CeO2 showed a small dielectric loss (tan delta). The interfacial polarization effect was confirmed by low-frequency dielectric dispersion in epsilon ” and epsilon r. The large conductivity coupled with a relaxation phenomenon at higher temperatures is attributed to the shift from extended hopping to localized ionic transport. Ce0.8Zr0.2O2 showed a negative coefficient of resistance validated through increasing ac conductivity with temperature. A high dielectric constant with small dielectric tangent loss achieved in cubic structured sample established its application in high-performance metal oxide semiconductor field effect transistor (MOSFET) devices along with the formation of advanced solid-electrolytes for solid oxide fuel cells. |
|
Accession Number:
WOS:001250021200001
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Ce0.8Zr0.2O2; fuel cell; MOSFET; X-ray diffraction; Rietveld refinement; dielectric properties |
|
KeyWords Plus:
OXIDE; CONDUCTIVITY |
Addresses:
[Kumari, Sushama; Atal, Krishna; Bugalia, Swati] Univ Rajasthan, Dept Chem, Jaipur 302004, India.
[Sharma, Saurabh Kumar] Rensselaer Polytech Inst, Mech Aerosp & Nucl Engn Dept, Troy, NY 12180 USA.
[Meena, Ramcharan] Interuniv Accelerator Ctr, Mat Sci Grp, New Delhi 110067, India.
[Goel, Vijay Kumar] Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India. |
|
Corresponding Address:
Bugalia, S (corresponding author), Univ Rajasthan, Dept Chem, Jaipur 302004, India. |
|
E-mail Addresses:
swati.bugalia@gmail.com |
|
Affiliations:
University of Rajasthan; Rensselaer Polytechnic Institute; Inter-University Accelerator Centre; Jawaharlal Nehru University, New Delhi |
|
Publisher:
INDIAN ACAD SCIENCES
|
|
Publisher Address:
C V RAMAN AVENUE, SADASHIVANAGAR, P B #8005, BANGALORE 560 080, INDIA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Materials Science, Multidisciplinary |
|
Research Areas:
Materials Science |
|
IDS Number:
US3Z4
|
|
ISSN:
0250-4707
|
|
eISSN:
0973-7669
|
|
29-char Source Abbrev.:
B MATER SCI
|
|
ISO Source Abbrev.:
Bull. Mat. Sci.
|
|
Source Item Page Count:
9
|
| Funding: |
| Funding Agency | Grant Number |
|
Council of Scientific and Industrial Research, Goverment of India |
09/149(0799)/2020-EMR-I
|
|
|
Sushama Kumari acknowledges the Council of Scientific and Industrial Research, Goverment of India, for awarding the Senior Research Fellowship with reference number 09/149(0799)/2020-EMR-I.
|
|
Output Date:
2024-07-01
|
| Record 33 of 44 |
|
Title:
Surgical Tumor Resection Deregulates Hallmarks of Cancer in Resected Tissue and the Surrounding Microenvironment
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|
Author(s):
Chaubal, R (Chaubal, Rohan); Gardi, N (Gardi, Nilesh); Joshi, S (Joshi, Shalaka); Pantvaidya, G (Pantvaidya, Gouri); Kadam, R (Kadam, Rasika); Vanmali, V (Vanmali, Vaibhav); Hawaldar, R (Hawaldar, Rohini); Talker, E (Talker, Elizabeth); Chitra, J (Chitra, Jaya); Gera, P (Gera, Poonam); Bhatia, D (Bhatia, Dimple); Kalkar, P (Kalkar, Prajakta); Gurav, M (Gurav, Mamta); Shetty, O (Shetty, Omshree); Desai, S (Desai, Sangeeta); Krishnan, NM (Krishnan, Neeraja M.); Nair, N (Nair, Nita); Parmar, V (Parmar, Vani); Dutt, A (Dutt, Amit); Panda, B (Panda, Binay); Gupta, S (Gupta, Sudeep); Badwe, R (Badwe, Rajendra) |
| Source:
MOLECULAR CANCER RESEARCH Volume:
22 Issue:
6 Pages:
572-584 Published Date:
2024 JUN 4 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
95
|
|
Abstract:
Surgery exposes tumor tissue to severe hypoxia and mechanical stress leading to rapid gene expression changes in the tumor and its microenvironment, which remain poorly characterized. We biopsied tumor and adjacent normal tissues from patients with breast (n = 81) and head/neck squamous cancers (HNSC; n = 10) at the beginning (A), during (B), and end of surgery (C). Tumor/normal RNA from 46/81 patients with breast cancer was subjected to mRNA-Seq using Illumina short-read technology, and from nine patients with HNSC to whole-transcriptome microarray with Illumina BeadArray. Pathways and genes involved in 7 of 10 known cancer hallmarks, namely, tumor-promoting inflammation (TNF-A, NFK-B, IL18 pathways), activation of invasion and migration (various extracellular matrix-related pathways, cell migration), sustained proliferative signaling (K-Ras Signaling), evasion of growth suppressors (P53 signaling, regulation of cell death), deregulating cellular energetics (response to lipid, secreted factors, and adipogenesis), inducing angiogenesis (hypoxia signaling, myogenesis), and avoiding immune destruction (CTLA4 and PDL1) were significantly deregulated during surgical resection (time points A vs. B vs. C). These findings were validated using NanoString assays in independent pre/intra/post-operative breast cancer samples from 48 patients. In a comparison of gene expression data from biopsy (analogous to time point A) with surgical resection samples (analogous to time point C) from The Cancer Genome Atlas study, the top deregulated genes were the same as identified in our analysis, in five of the seven studied cancer types. This study suggests that surgical extirpation deregulates the hallmarks of cancer in primary tumors and adjacent normal tissue across different cancers.Implications: Surgery deregulates hallmarks of cancer in human tissue. |
|
Accession Number:
WOS:001239198100006
|
|
Language:
English |
|
Document Type:
Article |
|
KeyWords Plus:
INFLUENCING HEPATIC METASTASES; GENE-EXPRESSION; BREAST-CANCER; MOLECULAR PORTRAITS; DRUG-ADDICTION; HYPOXIA; SURGERY; AP-1; CLASSIFICATION; RESISTANCE |
Addresses:
[Chaubal, Rohan; Joshi, Shalaka; Pantvaidya, Gouri; Chitra, Jaya; Nair, Nita; Parmar, Vani; Badwe, Rajendra] Tata Mem Hosp, Tata Mem Ctr, Dept Surg Oncol, Mumbai, India.
[Chaubal, Rohan; Gardi, Nilesh; Joshi, Shalaka; Talker, Elizabeth; Chitra, Jaya; Bhatia, Dimple; Kalkar, Prajakta; Nair, Nita; Gupta, Sudeep; Badwe, Rajendra] Tata Mem Hosp, Adv Ctr Treatment Res & Educ Canc, Clinician Scientist Lab, Hypoxia & Clin Genom Lab, Navi Mumbai, Maharashtra, India.
[Chaubal, Rohan; Gardi, Nilesh; Joshi, Shalaka; Pantvaidya, Gouri; Kadam, Rasika; Vanmali, Vaibhav; Hawaldar, Rohini; Gurav, Mamta; Shetty, Omshree; Desai, Sangeeta; Nair, Nita; Parmar, Vani; Dutt, Amit; Gupta, Sudeep; Badwe, Rajendra] Homi Bhabha Natl Inst, Training Sch Complex, Mumbai, Maharashtra, India.
[Gardi, Nilesh; Kadam, Rasika; Talker, Elizabeth; Gupta, Sudeep] Tata Mem Hosp, Tata Mem Ctr, Dept Med Oncol, Mumbai, India.
[Vanmali, Vaibhav; Hawaldar, Rohini] Tata Mem Hosp, Tata Mem Ctr, Clin Res Secretariat, Mumbai, India.
[Gera, Poonam] Tata Mem Hosp, Adv Ctr Treatment Res & Educ Canc, Biorepository, Navi Mumbai, Maharashtra, India.
[Gurav, Mamta; Shetty, Omshree; Desai, Sangeeta] Tata Mem Hosp, Tata Mem Ctr, Dept Pathol, Mumbai, India.
[Krishnan, Neeraja M.; Panda, Binay] Jawaharlal Nehru Univ, Sch Biotechnol, New Delhi, India.
[Parmar, Vani] Tata Mem Hosp, Adv Ctr Treatment Res & Educ Canc, 3D Printing Lab, Navi Mumbai, Maharashtra, India.
[Dutt, Amit] Tata Mem Hosp, Adv Ctr Treatment Res & Educ Canc, Integrated Canc Genom Lab, Kharghar 410210, Navi Mumbai, India.
[Badwe, Rajendra] Tata Mem Hosp, Dr E Borges Rd, Mumbai 400012, Maharashtra, India. |
Corresponding Address:
Gupta, S; Badwe, R (corresponding author), Tata Mem Hosp, Adv Ctr Treatment Res & Educ Canc, Clinician Scientist Lab, Hypoxia & Clin Genom Lab, Navi Mumbai, Maharashtra, India.
Gupta, S; Badwe, R (corresponding author), Homi Bhabha Natl Inst, Training Sch Complex, Mumbai, Maharashtra, India.
Gupta, S (corresponding author), Tata Mem Hosp, Tata Mem Ctr, Dept Med Oncol, Mumbai, India.
Badwe, R (corresponding author), Tata Mem Hosp, Dr E Borges Rd, Mumbai 400012, Maharashtra, India. |
|
E-mail Addresses:
badwera@tmc.gov.in; sudeep.gupta@actrec.gov.in |
|
Affiliations:
Tata Memorial Centre (TMC); Tata Memorial Hospital; Tata Memorial Centre (TMC); Advance Centre for Treatment, Research & Education in Cancer (ACTREC); Tata Memorial Hospital; Homi Bhabha National Institute; Tata Memorial Centre (TMC); Tata Memorial Hospital; Tata Memorial Centre (TMC); Tata Memorial Hospital; Tata Memorial Centre (TMC); Tata Memorial Hospital; Advance Centre for Treatment, Research & Education in Cancer (ACTREC); Tata Memorial Centre (TMC); Tata Memorial Hospital; Jawaharlal Nehru University, New Delhi; Tata Memorial Centre (TMC); Tata Memorial Hospital; Advance Centre for Treatment, Research & Education in Cancer (ACTREC); Tata Memorial Centre (TMC); Tata Memorial Hospital; Advance Centre for Treatment, Research & Education in Cancer (ACTREC); Tata Memorial Centre (TMC); Tata Memorial Hospital |
|
Publisher:
AMER ASSOC CANCER RESEARCH
|
|
Publisher Address:
615 CHESTNUT ST, 17TH FLOOR, PHILADELPHIA, PA 19106-4404 USA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Oncology; Cell Biology |
|
Research Areas:
Oncology; Cell Biology |
|
IDS Number:
TD0F4
|
|
ISSN:
1541-7786
|
|
eISSN:
1557-3125
|
|
29-char Source Abbrev.:
MOL CANCER RES
|
|
ISO Source Abbrev.:
Mol. Cancer Res.
|
|
Source Item Page Count:
13
|
| Funding: |
| Funding Agency | Grant Number |
|
Department of Atomic Energy, Government of India (DAE) | |
|
Department of Atomic Energy, Government of India (GOI) | |
|
Women’s Cancer Initiative (WCI)-Tata Memorial Hospital – HBNI, Mumbai |
BT/MED/30/VNCI-Hr-BRCA/2015
|
|
TMC, Mumbai – Department of Biotechnology (DBT), GOI, through the DBT-Virtual National Cancer Institute (VNCI) Breast Cancer | |
|
Department of Science and Technology (DST)-Scientific Engineering and Research Board (SERB) Prime Minister’s Fellowship | |
|
|
This study was funded by the Department of Atomic Energy, Government of India (GOI). We acknowledge the generous support and funding received from Sunil Gupta for the NanoString nCounter Assays. We also acknowledge funding from Mizuho Bank Limited for research infrastructure at our institute. We are thankful to Akhil Gupta for funding laboratory infrastructure. We acknowledge part research funding for this study from the Women’s Cancer Initiative (WCI)-Tata Memorial Hospital. R. Chaubal and N. Gardi were funded by a fellowship from HBNI, Mumbai, and TMC, Mumbai. R. Chaubal, N. Gardi, and R. Kadam are also funded by a fellowship from the Department of Biotechnology (DBT), GOI, through the DBT-Virtual National Cancer Institute (VNCI) Breast Cancer 2015 grant (BT/MED/30/VNCI-Hr-BRCA/2015) awarded (to S. Gupta). N. Gardi is also funded by the Department of Science and Technology (DST)-Scientific Engineering and Research Board (SERB) Prime Minister’s Fellowship.
|
|
Output Date:
2024-07-01
|
| Record 34 of 44 |
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Title:
Novel mutations found in <i>Mycobacterium leprae</i> DNA repair gene nth from central India
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|
Author(s):
Sharma, M (Sharma, Mukul); Dwivedi, P (Dwivedi, Purna); Joshi, V (Joshi, Vandana); Singh, P (Singh, Pushpendra) |
| Source:
JOURNAL OF INFECTION AND CHEMOTHERAPY Volume:
30 Issue:
6 Pages:
531-535 DOI:
10.1016/j.jiac.2023.12.011 Published Date:
2024 JUN |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
25
|
|
Abstract:
Introduction: The importance of DNA repair enzymes in maintaining genomic integrity is highlighted by the hypothesis that DNA damage by reactive oxygen/nitrogen species produced inside the host cell is essential for the mutagenesis process. Endonuclease III (Nth), formamidopyrimide (Fpg) and endonuclease VIII (Nei) DNA glycosylases are essential components of the bacterial base excision repair process. Mycobacterium leprae lost both fpg/nei genes during the reductive evolution event and only has the nth (ML2301) gene. This study aims to characterize the mutations in the nth gene of M. leprae strains and explore its correlation with drug -resistance. Method: A total of 91 M. leprae positive DNA samples extracted from skin biopsy samples of newly diagnosed leprosy patients from NSCB Hospital Jabalpur were assessed for the nth gene as well as drug resistance -associated loci of the rpoB, gyrA and folP1 genes through PCR followed by Sanger sequencing. Results: Of these 91 patients, a total of two insertion frameshift mutations, two synonymous and seven nonsynonymous mutations were found in nth in seven samples. Sixteen samples were found to be resistant to ofloxacin and one was found to be dapsone resistant as per the known DRDR mutations. No mutations were found in the rpoB region. Interestingly, none of the nth mutations were identified in the drug -resistant associated samples. Conclusion: The in-silico structural analysis of the non -synonymous mutations in the Nth predicted five of them were to be deleterious. Our results suggest that the mutations in the nth gene may be potential markers for phylogenetic and epidemiological studies. |
|
Accession Number:
WOS:001233102700001
|
|
PubMed ID:
38141720
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Mycobacterium leprae; nth; DNA repair gene; Drug resistance; Molecular epidemiology; Mutation |
|
KeyWords Plus:
ESCHERICHIA-COLI NTH; EFFICIENT REPAIR; GLYCOSYLASES; DAMAGE; RESISTANCE; PATHWAYS; HOMOLOGS; EXCISION |
Addresses:
[Sharma, Mukul; Dwivedi, Purna; Joshi, Vandana; Singh, Pushpendra] ICMR Natl Inst Res Tribal Hlth, Jabalpur, Madhya Pradesh, India.
[Dwivedi, Purna] Maharaja Sayajirao Univ Baroda, Vadodara, Gujarat, India.
[Joshi, Vandana] Jawaharlal Nehru Univ, Sch Biotechnol, New Delhi, India.
[Singh, Pushpendra] ICMR NIRTH, Jabalpur 482003, Madhya Pradesh, India. |
|
Corresponding Address:
Singh, P (corresponding author), ICMR NIRTH, Jabalpur 482003, Madhya Pradesh, India. |
|
E-mail Addresses:
Pushpendra.S@icmr.gov.in |
|
Affiliations:
Indian Council of Medical Research (ICMR); ICMR – National Institute for Research in Tribal Health (NIRTH); Maharaja Sayajirao University Baroda; Jawaharlal Nehru University, New Delhi |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Dwivedi, Purna | | 0000-0002-3132-4716 |
|
JOSHI, VANDANA | | 0009-0003-6151-3774 |
|
|
Publisher:
ELSEVIER
|
|
Publisher Address:
RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Infectious Diseases; Pharmacology & Pharmacy |
|
Research Areas:
Infectious Diseases; Pharmacology & Pharmacy |
|
IDS Number:
SF7H9
|
|
ISSN:
1341-321X
|
|
eISSN:
1437-7780
|
|
29-char Source Abbrev.:
J INFECT CHEMOTHER
|
|
ISO Source Abbrev.:
J. Infect. Chemother.
|
|
Source Item Page Count:
5
|
| Funding: |
| Funding Agency | Grant Number |
|
R2STOP (effect:hope TLM) Canada | |
|
Turing Foundation and Leprosy Research Initiative (LRI) Netherlands | |
|
Department of Biotechnology (Government of India) | |
|
Indian Council of Medical Research (ICMR) | |
|
ICMR-RA | |
|
ICMR- SRF | |
|
|
The authors thank Afzal Ansari for submitting the sequence into the database. The manuscript has been approved by the Publication Screening Committee of ICMR-NIRTH, Jabalpur and assigned with the number ICMR-NIRTH/PSC/27/2023. Research work of P.S. is funded in part by R2STOP (effect:hope TLM) Canada, Turing Foundation and Leprosy Research Initiative (LRI) Netherlands, the Department of Biotechnology (Government of India) and Indian Council of Medical Research (ICMR) . MS and PD are the recipient of ICMR-RA and ICMR- SRF fellowships, respectively.
|
|
Output Date:
2024-07-01
|
| Record 35 of 44 |
|
Title:
Mechanistic Insights into Cellular and Molecular Targets of Zinc Oxide Quantum Dots (ZnO QDs) in Fungal Pathogen, Candida albicans: One Drug Multi-Targeted Therapeutic Approach
|
|
Author(s):
Chand, P (Chand, Preeti); Narula, K (Narula, Kritika); Radhakrishnan, VS (Radhakrishnan, V. S.); Sharma, S (Sharma, Shubham); Kumari, S (Kumari, Sangeeta); Mondal, N (Mondal, Neelima); Singh, SP (Singh, Surinder P.); Mishra, P (Mishra, Prashant); Prasad, T (Prasad, Tulika) |
| Source:
ACS INFECTIOUS DISEASES Volume:
10 Issue:
6 Pages:
1914-1934 DOI:
10.1021/acsinfecdis.3c00562 Early Access Date:
JUN 2024 Published Date:
2024 JUN 4 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
67
|
|
Abstract:
Rationally designed multitargeted drugs, known as network therapeutics/multimodal drugs, have emerged as versatile therapeutic solutions to combat drug-resistant microbes. Here, we report novel mechanistic insights into cellular and molecular targets of ZnO quantum dots (QDs) against Candida albicans, a representative of fungal pathogens. Stable, monodispersed 4-6 nm ZnO QDs were synthesized using a wet chemical route, which exhibited dose-dependent inhibition on the growth dynamics of Candida. Treatment with 200 mu g/mL ZnO QDs revealed an aberrant morphology and a disrupted cellular ultrastructure in electron microscopy and led to a 23% reduction in ergosterol content and a 53% increase in intracellular reactive oxygen species. Significant increase in steady-state fluorescence polarization and fluorescence lifetime decay of membrane probe 1,6-diphenyl-1,3,5-hexatriene (DPH) in treated cells, respectively, implied reduction in membrane fluidity and enhanced microviscosity. The observed reduction in passive diffusion of fluorescent Rhodamine 6G across the membrane validated the intricate relationship between ergosterol, membrane fluidity, and microviscosity. An inverse relationship existing between ergosterol biosynthetic genes, ERG11 and ERG3 in treated cells, related well with displayed higher susceptibilities. Furthermore, treated cells exhibited impaired functionality and downregulation of ABC drug efflux pumps. Multiple cellular targets of ZnO QDs in Candida were validated by in silico molecular docking. Thus, targeting ERG11, ERG3, and ABC drug efflux pumps might emerge as a versatile, nano-ZnO-based strategy in fungal therapeutics to address the challenges of drug resistance. |
|
Accession Number:
WOS:001239418800001
|
|
PubMed ID:
38831663
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
ZnO quantum dots; mechanistic action; drugefflux pumps; membrane fluidity; drug resistance; multitargeted antifungal |
|
KeyWords Plus:
MULTIDRUG-RESISTANCE; MEMBRANE-FLUIDITY; NANOPARTICLES; SUSCEPTIBILITIES; ACCURACY; UPDATE |
Addresses:
[Chand, Preeti; Radhakrishnan, V. S.; Prasad, Tulika] Jawaharlal Nehru Univ, Special Ctr Nano Sci & AIRF, New Delhi 110067, India.
[Narula, Kritika; Sharma, Shubham; Mishra, Prashant] Indian Inst Technol Delhi, Biochem Engn & Biotechnol, New Delhi 110016, India.
[Kumari, Sangeeta; Mondal, Neelima] Jawaharlal Nehru Univ, Sch Life Sci, New Delhi 110067, India.
[Singh, Surinder P.] CSIR Natl Phys Lab, New Delhi 110012, India. |
|
Corresponding Address:
Prasad, T (corresponding author), Jawaharlal Nehru Univ, Special Ctr Nano Sci & AIRF, New Delhi 110067, India. |
|
E-mail Addresses:
prasadtulika@hotmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) – Delhi; Jawaharlal Nehru University, New Delhi; Council of Scientific & Industrial Research (CSIR) – India; CSIR – National Physical Laboratory (NPL) |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
PRASAD, TULIKA | | 0000-0003-1617-8375 |
|
|
Publisher:
AMER CHEMICAL SOC
|
|
Publisher Address:
1155 16TH ST, NW, WASHINGTON, DC 20036 USA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Chemistry, Medicinal; Infectious Diseases |
|
Research Areas:
Pharmacology & Pharmacy; Infectious Diseases |
|
IDS Number:
UI8X4
|
|
ISSN:
2373-8227
|
|
29-char Source Abbrev.:
ACS INFECT DIS
|
|
ISO Source Abbrev.:
ACS Infect. Dis.
|
|
Source Item Page Count:
21
|
| Funding: |
| Funding Agency | Grant Number |
|
Jawaharlal Nehru University |
5/8/5/1/Adhoc/2020/ECD-I
35/11/2019-Nano/BMS
35/02/2022-NAN/BMS
ID-161
|
|
ICMR | |
|
Council of Scientific and Industrial Research (CSIR), India | |
|
Ministry of Human Resource Development (MHRD) | |
|
|
TP gratefully acknowledges ICMR Grants (F. No. 5/8/5/1/Adhoc/2020/ECD-I; F. No. 35/11/2019-Nano/BMS dated 7/10/19; F. No. 35/02/2022-NAN/BMS), JNU-UPOE II scheme (ID-161) and JNU-DST-PURSE (Phase-II), India. PC gratefully thanks the Council of Scientific and Industrial Research (CSIR), India for providing a Senior Research Fellowship. KN is highly grateful to the Ministry of Human Resource Development (MHRD), Govt. of India for providing the Senior Research fellowship. The infrastructural facilities of JNU are sincerely acknowledged.
|
|
Output Date:
2024-07-01
|
| Record 36 of 44 |
|
Title:
Structural and photoluminescence properties of terbium (III) activated Li<sub>2</sub>SiO<sub>3</sub> phosphors: an approach for bluish-green light emission
|
|
Author(s):
Barik, P (Barik, Priya); Verma, AK (Verma, Aksh Kumar); Kumar, R (Kumar, Ravinder); Kumar, V (Kumar, Vinod); Dewangan, P (Dewangan, Pradeep); Sahu, M (Sahu, Manorama); Sahu, IP (Sahu, Ishwar Prasad) |
| Source:
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING Volume:
130 Issue:
6 Article Number:
391 DOI:
10.1007/s00339-024-07525-4 Published Date:
2024 JUN |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
58
|
|
Abstract:
In this paper, a series of bluish-green emitting Li2SiO3:xTb(3+)(x = 0.01, 0.02, 0.03, 0.04 and 0.05 mol) phosphors were synthesized by solid state reaction method. The effects of Tb3+ doping concentration on photoluminescence (PL) properties of Li2SiO3:xTb(3+) were investigated. Powder X-ray diffraction (PXRD) analysis show that the prepared phosphors confirm the sample has orthorhombic crystal structure. Energy dispersive X-ray analysis (EDX) shown that Tb element are uniformly doped in Li2SiO3 phosphor with a proper stoichiometric ratio. UV-Visible absorption spectroscopy was used to determine the band gap of Li2SiO3:0.04Tb(3+) phosphor. The near ultraviolet light at the wavelength of 379 nm can excite this phosphor and exhibits blue emission at 484 nm at transition D-5(3) -> F-7(6), and green emission at 541 nm at transition D-5(4) -> F-7(5.) The critical quenching concentration of Tb3+ in Li(2)SiO(3)host is 0.04 mol(.) The life time measurements were also performed for Li2SiO3:0.04Tb(3+) phosphor and estimated average life time. From the photometric properties result indicates that prepared phosphors were emit bluish-green light and they were useful for the solid state lighting applications. |
|
Accession Number:
WOS:001220357200002
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Li2SiO3:xTb(3+) phosphors; Photoluminescence; Critical quenching; Photometric properties |
|
KeyWords Plus:
CONDITION HYDROTHERMAL SYNTHESIS; ENERGY-TRANSFER; LUMINESCENCE PROPERTIES; LITHIUM METASILICATE; TB; EU3+; UV; TEMPERATURE; OXIDE; SM3+ |
Addresses:
[Barik, Priya; Sahu, Ishwar Prasad] Indira Gandhi Natl Tribal Univ, Dept Phys, Amarkantak 484887, Madhya Pradesh, India.
[Verma, Aksh Kumar] Pt Ravishankar Shukla Univ, Sch Studies Phys & Astrophys, Raipur 492010, Chhattisgarh, India.
[Kumar, Ravinder] GurukulaKangri, Dept Chem, Haridwar 249404, Uttaranchal, India.
[Kumar, Vinod] Jawaharlal Nehru Univ, Special Ctr Nanosci, Delhi 110067, India.
[Dewangan, Pradeep; Sahu, Manorama] Shri Shankaracharya Inst Profess Management & Tech, Dept Phys, Raipur 492015, Chhattisgarh, India.
[Sahu, Manorama] Govt Polytech, Dept Phys, Kabirdham 491995, Chhattisgarh, India. |
|
Corresponding Address:
Sahu, IP (corresponding author), Indira Gandhi Natl Tribal Univ, Dept Phys, Amarkantak 484887, Madhya Pradesh, India. |
|
E-mail Addresses:
ishwarprasad1986@gmail.com |
|
Affiliations:
Indira Gandhi National Tribal University; Pt. Ravishankar Shukla University; Jawaharlal Nehru University, New Delhi |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Barik, Priya | KBQ-3621-2024 | 0009-0004-5172-8592 |
|
|
Publisher:
SPRINGER HEIDELBERG
|
|
Publisher Address:
TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Materials Science, Multidisciplinary; Physics, Applied |
|
Research Areas:
Materials Science; Physics |
|
IDS Number:
QI9F4
|
|
ISSN:
0947-8396
|
|
eISSN:
1432-0630
|
|
29-char Source Abbrev.:
APPL PHYS A-MATER
|
|
ISO Source Abbrev.:
Appl. Phys. A-Mater. Sci. Process.
|
|
Source Item Page Count:
19
|
| Funding: |
| Funding Agency | Grant Number |
|
University Grants Commission- India |
CRG/2018/004139
|
|
Science & Engineering Research Board (SERB), New Delhi, Government of India | |
|
|
The corresponding author; Dr. Ishwar Prasad Sahu, would like to acknowledge the Science & Engineering Research Board (SERB), New Delhi, Government of India for funding FTIR Spectrophotometer (CRG/2018/004139). This instrument is used for the IR spectroscopic analysis of the prepared sample from the study.
|
|
Output Date:
2024-07-01
|
| Record 37 of 44 |
|
Title:
Intermolecular Interaction Mediated Potassium Ion Intercalation Chemistry in Ether-Based Electrolyte for Potassium-Ion Batteries
|
|
Author(s):
Xie, HL (Xie, Hongliang); Liang, HH (Liang, Honghong); Kumar, P (Kumar, Pushpendra); Cheng, HR (Cheng, Haoran); Zhao, F (Zhao, Fei); Wang, YQ (Wang, Yuqi); Cai, T (Cai, Tao); Wahyudi, W (Wahyudi, Wandi); Ma, Z (Ma, Zheng); Li, Q (Li, Qian); Ming, J (Ming, Jun) |
| Source:
ADVANCED FUNCTIONAL MATERIALS DOI:
10.1002/adfm.202401118 Early Access Date:
JUN 2024 Published Date:
2024 JUN 4 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
55
|
|
Abstract:
Electrolyte design is indeed a highly effective strategy to improve battery performance. However, identifying the intermolecular interaction in electrolyte solvation structure is rarely reported in potassium-ion batteries. Herein, it is discovered that a solvent-solvent intermolecular interaction can be formed when introducing the cyclopentylmethyl ether (CPME) solvent into the commonly used 1,2-dimethoxyethane (DME)-based electrolytes. Such interaction is not only analyzed by 2D H-1-H-1 correlation spectroscopy for the first time but also found that it can weaken the K+-DME interaction significantly, consequently enabling a reversible K+ (de-)intercalation within the graphite. By employing this strategy without using any fluorine-based solvent, a new fluorine-free and low-concentration ether-based electrolyte is designed, which is not only compatible with graphite but also facilitates the design of high-energy-density and safe potassium ion sulfur batteries. A novel molecular interfacial model is further presented to analyze the interfacial behaviors of K+-solvent-anion complexes on the electrode surface that are affected by intermolecular interactions, elucidating the reasons behind the superior electrolyte compatibility and graphite electrode performance at the molecular scale. This work sheds some light on the critical role of solvent-solvent interactions in electrolyte design for potassium-ion batteries and provides valuable insights for engineering and enhancing the performance of electrolytes and batteries. |
|
Accession Number:
WOS:001239134100001
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
electrolyte; graphite anode; intermolecular interactions; potassium-ion batteries; solvation structure |
|
KeyWords Plus:
INTERFACIAL MODEL; GRAPHITE; ANODE |
Addresses:
[Xie, Hongliang; Liang, Honghong; Cheng, Haoran; Zhao, Fei; Wang, Yuqi; Cai, Tao; Ma, Zheng; Li, Qian; Ming, Jun] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Rare Earth Resource Utilizat, Changchun 130022, Peoples R China.
[Liang, Honghong; Cheng, Haoran; Zhao, Fei; Wang, Yuqi; Cai, Tao; Ming, Jun] Univ Sci & Technol China, Sch Appl Chem & Engn, Hefei 230026, Peoples R China.
[Kumar, Pushpendra] Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India.
[Wahyudi, Wandi] King Abdullah Univ Sci & Technol, Mat Sci & Engn, Thuwal 239556900, Saudi Arabia. |
Corresponding Address:
Ming, J (corresponding author), Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Rare Earth Resource Utilizat, Changchun 130022, Peoples R China.
Ming, J (corresponding author), Univ Sci & Technol China, Sch Appl Chem & Engn, Hefei 230026, Peoples R China. |
|
E-mail Addresses:
jun.ming@ciac.ac.cn |
|
Affiliations:
Chinese Academy of Sciences; Changchun Institute of Applied Chemistry, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Jawaharlal Nehru University, New Delhi; King Abdullah University of Science & Technology |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Ming, Jun | B-5193-2016 | 0000-0001-9561-5718 |
|
Ming, Jun | | 0009-0001-6422-069X |
|
|
Publisher:
WILEY-V C H VERLAG GMBH
|
|
Publisher Address:
POSTFACH 101161, 69451 WEINHEIM, GERMANY
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter |
|
Research Areas:
Chemistry; Science & Technology – Other Topics; Materials Science; Physics |
|
IDS Number:
TC7U1
|
|
ISSN:
1616-301X
|
|
eISSN:
1616-3028
|
|
29-char Source Abbrev.:
ADV FUNCT MATER
|
|
ISO Source Abbrev.:
Adv. Funct. Mater.
|
|
Source Item Page Count:
11
|
| Funding: |
| Funding Agency | Grant Number |
|
National Natural Science Foundation of China | |
|
Postdoctoral Fellowship Program of CPSF |
GZB20230835
|
|
Bureau of International Cooperation Chinese Academy of Sciences |
CAS-NST
121522KYSB20200047
|
|
Scientific and Technological Developing Project of Jilin Province |
YDZJ202101ZYTS022
20230101028JC
|
| |
22109155
|
| |
22122904
|
| |
22379136
|
| |
U21A20330
|
|
|
The authors greatly thank the funding support from the National Natural Science Foundation of China (22109155, 22122904, 22379136, U21A20330) and the Postdoctoral Fellowship Program of CPSF (GZB20230835). The authors also thank the Bureau of International Cooperation Chinese Academy of Sciences, CAS-NST Joint Research Projects (121522KYSB20200047), and the Scientific and Technological Developing Project of Jilin Province (YDZJ202101ZYTS022, 20230101028JC). The computational work was done on the KAUST supercomputer.
|
|
Output Date:
2024-07-01
|
| Record 38 of 44 |
|
Title:
Unusual Dzyaloshinskii-Moriya Interaction in Graphene/Fe<sub>3</sub>GeTe<sub>2</sub> Van der Waals Heterostructure
|
|
Author(s):
Srivastava, PK (Srivastava, Pawan Kumar); Hassan, Y (Hassan, Yasir); Lee, S (Lee, Seungjun); Joe, M (Joe, Minwoong); Abbas, MS (Abbas, Muhammad Sabbtain); Ahn, H (Ahn, Hyobin); Tiwari, A (Tiwari, Ankita); Ghosh, S (Ghosh, Subhasis); Yoo, WJ (Yoo, Won Jong); Singh, B (Singh, Budhi); Low, T (Low, Tony); Lee, C (Lee, Changgu) |
| Source:
SMALL DOI:
10.1002/smll.202402604 Early Access Date:
JUN 2024 Published Date:
2024 JUN 19 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
59
|
|
Abstract:
Dzyaloshinskii-Moriya interaction (DMI) is shown to induce a topologically protected chiral spin texture in magnetic/nonmagnetic heterostructures. In the context of van der Waals spintronic devices, graphene emerges as an excellent candidate material. However, due to its negligible spin-orbit interaction, inducing DMI to stabilize topological spins when coupled to 3d-ferromagnets remains challenging. Here, it is demonstrated that, despite these challenges, a sizeable Rashba-type spin splitting followed by significant DMI is induced in graphene/Fe3GeTe2. This is made possible due to an interfacial electric field driven by charge asymmetry together with the broken inversion symmetry of the heterostructure. These findings reveal that the enhanced DMI energy parameter, resulting from a large effective electron mass in Fe3GeTe2, remarkably contributes to stabilizing non-collinear spins below the Curie temperature, overcoming the magnetic anisotropy energy. These results are supported by the topological Hall effect, which coexists with the non-trivial breakdown of Fermi liquid behavior, confirming the interplay between spins and non-trivial topology. This work paves the way toward the design and control of interface-driven skyrmion-based devices. |
|
Accession Number:
WOS:001251193100001
|
|
PubMed ID:
38898739
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
Dzyaloshinskii-Moriya Interaction; Fe3GeTe2; magnetic anisotropy energy; non-Fermi liquid; Rashba effect; topological Hall effect |
|
KeyWords Plus:
NON-FERMI LIQUID; METAL; TEMPERATURE; SKYRMIONS; GRAPHENE |
Addresses:
[Srivastava, Pawan Kumar; Singh, Budhi] Sungkyunkwan Univ, Sch Mech Engn, Suwon 16419, South Korea.
[Hassan, Yasir; Joe, Minwoong; Lee, Changgu] Chungnam Natl Univ, Dept Mat Sci & Engn, 99 Daehak Ro, Daejeon 34143, South Korea.
[Lee, Seungjun; Low, Tony] Univ Minnesota, Dept Elect & Comp Engn, Minneapolis, MN 55455 USA.
[Abbas, Muhammad Sabbtain] Govt Coll Univ Lahore, Ctr Adv Studies Phys, Lahore 54000, Pakistan.
[Ahn, Hyobin; Yoo, Won Jong; Lee, Changgu] Sungkyunkwan Univ, SKKU Adv Inst Nanotechnol SAINT, Suwon 16419, South Korea.
[Tiwari, Ankita; Ghosh, Subhasis] Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India. |
Corresponding Address:
Singh, B (corresponding author), Sungkyunkwan Univ, Sch Mech Engn, Suwon 16419, South Korea.
Lee, C (corresponding author), Chungnam Natl Univ, Dept Mat Sci & Engn, 99 Daehak Ro, Daejeon 34143, South Korea.
Low, T (corresponding author), Univ Minnesota, Dept Elect & Comp Engn, Minneapolis, MN 55455 USA.
Lee, C (corresponding author), Sungkyunkwan Univ, SKKU Adv Inst Nanotechnol SAINT, Suwon 16419, South Korea. |
|
E-mail Addresses:
budhisingh@skku.edu; tlow@umn.edu; peterlee@skku.edu |
|
Affiliations:
Sungkyunkwan University (SKKU); Chungnam National University; University of Minnesota System; University of Minnesota Twin Cities; Government College University Lahore; Sungkyunkwan University (SKKU); Jawaharlal Nehru University, New Delhi |
|
Publisher:
WILEY-V C H VERLAG GMBH
|
|
Publisher Address:
POSTFACH 101161, 69451 WEINHEIM, GERMANY
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter |
|
Research Areas:
Chemistry; Science & Technology – Other Topics; Materials Science; Physics |
|
IDS Number:
UW8M1
|
|
ISSN:
1613-6810
|
|
eISSN:
1613-6829
|
|
29-char Source Abbrev.:
SMALL
|
|
ISO Source Abbrev.:
Small
|
|
Source Item Page Count:
7
|
| Funding: |
| Funding Agency | Grant Number |
|
National Research Foundation of Korea |
2021R1I1A1A01050054
2021R111A1A01050297
2021R1A6A1A03043682,2021R1I1A1A01057416
2023005383,2021R1A6A3A14038837
RS-2023-00248011
|
|
Basic Science Research Program through the National Research Foundation of Korea (NRF) | |
|
Ministry of Education, Science and ICT of Korea |
SRFC-MA2102-02
|
|
Samsung Science and Technology Foundation | |
|
KISTI supercomputing center |
DMR-1921629
|
|
National Science Foundation (NSF) through the DMREF program | |
|
|
P.K.S., Y.H., and S.L. contributed equally to this work. This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) (2021R1I1A1A01050054, 2021R111A1A01050297, 2021R1A6A1A03043682,2021R1I1A1A01057416, 2023005383,2021R1A6A3A14038837, RS-2023-00248011), funded by the Ministry of Education, Science and ICT of Korea, Samsung Science and Technology Foundation (project no. SRFC-MA2102-02) and the KISTI supercomputing center (Grant No. KSC-2022-CRE-0325). S.L. and T.L. were supported by the National Science Foundation (NSF) through the DMREF program under Award No. DMR-1921629.
|
|
Output Date:
2024-07-01
|
| Record 39 of 44 |
|
Title:
Low-Temperature and Fast-Charging Lithium Metal Batteries Enabled by Solvent-Solvent Interaction Mediated Electrolyte
|
|
Author(s):
Huang, A (Huang, Akang); Ma, Z (Ma, Zheng); Kumar, P (Kumar, Pushpendra); Liang, HH (Liang, Honghong); Cai, T (Cai, Tao); Zhao, F (Zhao, Fei); Cao, Z (Cao, Zhen); Cavallo, L (Cavallo, Luigi); Li, Q (Li, Qian); Ming, J (Ming, Jun) |
| Source:
NANO LETTERS Volume:
24 Issue:
24 Pages:
7499-7507 DOI:
10.1021/acs.nanolett.4c01591 Early Access Date:
JUN 2024 Published Date:
2024 JUN 10 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
7 |
|
Usage Count
(Since 2013):
7 |
|
Cited Reference Count:
45
|
|
Abstract:
Lithium metal batteries utilizing lithium metal as the anode can achieve a greater energy density. However, it remains challenging to improve low-temperature performance and fast-charging features. Herein, we introduce an electrolyte solvation chemistry strategy to regulate the properties of ethylene carbonate (EC)-based electrolytes through intermolecular interactions, utilizing weakly solvated fluoroethylene carbonate (FEC) to replace EC, and incorporating the low-melting-point solvent 1,2-difluorobenzene (2FB) as a diluent. We identified that the intermolecular interaction between 2FB and solvent can facilitate Li+ desolvation and lower the freezing point of the electrolyte effectively. The resulting electrolyte enables the LiNi0.8Co0.1Mn0.1O2||Li cell to operate at -30 degrees C for more than 100 cycles while delivering a high capacity of 154 mAh g(-1) at 5.0C. We present a solvation structure and interfacial model to analyze the behavior of the formulated electrolyte composition, establishing a relationship with cell performance and also providing insights for the electrolyte design under extreme conditions. |
|
Accession Number:
WOS:001243957600001
|
|
PubMed ID:
38856230
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
lithium metal battery; low-temperature electrolyte; solvation structure; solvent-solvent interaction; Li+ desolvation process |
|
KeyWords Plus:
INTERFACIAL MODEL; RECHARGEABLE BATTERIES; ANTIMONY ANODE |
Addresses:
[Huang, Akang; Ma, Zheng; Liang, Honghong; Cai, Tao; Zhao, Fei; Li, Qian; Ming, Jun] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Rare Earth Resource Utilizat, Changchun 130022, Peoples R China.
[Huang, Akang; Liang, Honghong; Cai, Tao; Zhao, Fei; Ming, Jun] Univ Sci & Technol China, Sch Appl Chem & Engn, Hefei 230026, Peoples R China.
[Kumar, Pushpendra] Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India.
[Cao, Zhen; Cavallo, Luigi] King Abdullah Univ Sci & Technol KAUST, KAUST Catalysis Ctr, Thuwal 23955, Saudi Arabia. |
Corresponding Address:
Ma, Z; Li, Q; Ming, J (corresponding author), Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Rare Earth Resource Utilizat, Changchun 130022, Peoples R China.
Ming, J (corresponding author), Univ Sci & Technol China, Sch Appl Chem & Engn, Hefei 230026, Peoples R China. |
|
E-mail Addresses:
zheng.ma@ciac.ac.cn; qianli@ciac.ac.cn; jun.ming@ciac.ac.cn |
|
Affiliations:
Chinese Academy of Sciences; Changchun Institute of Applied Chemistry, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Jawaharlal Nehru University, New Delhi; King Abdullah University of Science & Technology |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Ming, Jun | B-5193-2016 | 0000-0001-9561-5718 |
|
Ming, Jun | | 0009-0001-6422-069X |
|
Cavallo, Luigi | D-5215-2019 | 0000-0002-1398-338X |
|
|
Publisher:
AMER CHEMICAL SOC
|
|
Publisher Address:
1155 16TH ST, NW, WASHINGTON, DC 20036 USA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter |
|
Research Areas:
Chemistry; Science & Technology – Other Topics; Materials Science; Physics |
|
IDS Number:
UU0R0
|
|
ISSN:
1530-6984
|
|
eISSN:
1530-6992
|
|
29-char Source Abbrev.:
NANO LETT
|
|
ISO Source Abbrev.:
Nano Lett.
|
|
Source Item Page Count:
9
|
| Funding: |
| Funding Agency | Grant Number |
|
National Natural Science Foundation of China |
22109155
22122904
22379136
U21A20330
|
|
National Natural Science Foundation of China |
121522KYSB20200047
|
|
Bureau of International Cooperation Chinese Academy of Sciences |
YDZJ202101ZYTS022
20230101028JC
|
|
Scientific and Technological Developing Project of Jilin Province | |
|
|
The authors greatly thank the funding support from the National Natural Science Foundation of China (22109155, 22122904, 22379136, U21A20330). The authors also thank the Bureau of International Cooperation Chinese Academy of Sciences, CAS-NST Joint Research Projects (121522KYSB20200047), and the Scientific and Technological Developing Project of Jilin Province (YDZJ202101ZYTS022, 20230101028JC). The computational work was done on the KAUST supercomputer.
|
|
Output Date:
2024-07-01
|
| Record 40 of 44 |
|
Title:
Investigation of Indian stock markets using topological data analysis and geometry-inspired network measures
|
|
Author(s):
Kulkarni, S (Kulkarni, Saumitra); Pharasi, HK (Pharasi, Hirdesh K.); Vijayaraghavan, S (Vijayaraghavan, Sudharsan); Kumar, S (Kumar, Sunil); Chakraborti, A (Chakraborti, Anirban); Samal, A (Samal, Aredjit) |
| Source:
PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS Volume:
643 Article Number:
129785 DOI:
10.1016/j.physa.2024.129785 Published Date:
2024 JUN 1 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
126
|
|
Abstract:
Financial markets are a quintessential example of complex systems wherein strategic connections arising through the trading (buying and selling) of different stocks gives rise to dynamic correlation patterns in stock prices. Network science based approaches have been employed for more than two decades to investigate the stock market as an inferential network, with nodes representing stocks and edges as pairwise cross -correlations between stock prices. However, a recent focus has been the characterization of the higher -order structure, beyond pairwise correlation, of such networks. To this end, geometry -inspired measures (such as discrete Ricci curvatures) and topological data analysis (TDA) based methods (such as persistent homology) have become attractive tools for characterizing the higher -order structure of networks representing the financial systems. In this study, our goal is to perform a comparative analysis of both these approaches, especially by assessing the fragility and systemic risk in the Indian stock markets, which is known for its high volatility and risk. To achieve this goal, we analyze the time series of daily log -returns of stocks comprising the National Stock Exchange (NSE) and the Bombay Stock Exchange (BSE). Specifically, our aim is to monitor the changes in standard network measures, edge -centric discrete Ricci curvatures, and persistent homology based topological measures computed from cross -correlation matrices of stocks. In this study, the edge -centric discrete Ricci curvatures have been employed for the first time in the analysis of the Indian stock markets. The Indian stock markets are known to be less diverse in comparison to the US market, and hence provides us an interesting example. Our results point that, among the persistent homology based topological measures, persistent entropy is simple and more robust than L 1 -norm and L 2 -norm of persistence landscape. In a broader comparison between network analysis and TDA, we highlight that the network analysis is sensitive to the way of constructing the networks (threshold or minimum spanning tree), as well as the threshold values used to construct the correlation -based threshold networks. On the other hand, the persistent homology is a more robust approach and is able to capture the higher -order interactions and eliminate noisy data in financial systems, since it does not take into account a single value of threshold but rather a range of values. |
|
Accession Number:
WOS:001240204400001
|
|
Language:
English |
|
Document Type:
Article |
|
Author Keywords:
Indian stock markets; Correlation-based threshold networks; Network geometry; Discrete Ricci curvatures; Topological data analysis; Persistent homology |
|
KeyWords Plus:
PERSISTENT HOMOLOGY; RICCI CURVATURE; INFORMATION |
Addresses:
[Kulkarni, Saumitra; Vijayaraghavan, Sudharsan; Samal, Aredjit] Inst Math Sci IMSc, CIT Campus, Chennai 600113, Tamil Nadu, India.
[Pharasi, Hirdesh K.] BML Munjal Univ, Sch Engn & Technol, Gurugram 122413, Haryana, India.
[Kumar, Sunil] Univ Delhi, Ramjas Coll, Dept Phys, Delhi 110007, India.
[Chakraborti, Anirban] Jawaharlal Nehru Univ, Sch Computat & Integrat Sci, New Delhi 110067, Delhi, India.
[Samal, Aredjit] HBNI, Mumbai 400094, Maharashtra, India. |
|
Corresponding Address:
Samal, A (corresponding author), Inst Math Sci IMSc, CIT Campus, Chennai 600113, Tamil Nadu, India. |
|
E-mail Addresses:
anirban@jnu.ac.in; asamal@imsc.res.in |
|
Affiliations:
Institute of Mathematical Sciences (IMSc) India; BML Munjal University; University of Delhi; Jawaharlal Nehru University, New Delhi; Homi Bhabha National Institute |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
Chakraborti, Anirban | A-4565-2010 | 0000-0002-6235-0204 |
|
Samal, Areejit | E-5422-2011 | |
|
PHARASI, HIRDESH KUMAR | IWM-4757-2023 | |
|
Kulkarni, Saumitra | | 0000-0001-8859-3207 |
|
PHARASI, HIRDESH KUMAR | | 0000-0002-6937-9237 |
|
Samal, Areejit | | 0000-0002-6796-9604 |
|
|
Publisher:
ELSEVIER
|
|
Publisher Address:
RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Physics, Multidisciplinary |
|
Research Areas:
Physics |
|
IDS Number:
TG8M2
|
|
ISSN:
0378-4371
|
|
eISSN:
1873-2119
|
|
29-char Source Abbrev.:
PHYSICA A
|
|
ISO Source Abbrev.:
Physica A
|
|
Source Item Page Count:
18
|
| Funding: |
| Funding Agency | Grant Number |
|
Max Planck Society, Germany through Max Planck Partner Group in Mathematical Biology | |
|
Department of Atomic Energy (DAE) , Government of India | |
|
Science and Engineering Research Board (SERB) , Department of Science and Technology, Government of India |
MTR/2020/000651
|
|
|
Areejit Samal would like to acknowledge support from the Max Planck Society, Germany, through the award of a Max Planck Partner Group in Mathematical Biology, and the Department of Atomic Energy (DAE) , Government of India, through the Apex project to The Institute of Mathematical Sciences (IMSc) , Chennai. Sunil Kumar would like to acknowledge the Science and Engineering Research Board (SERB) , Department of Science and Technology, Government of India for providing financial support via MATRICS grant [MTR/2020/000651] .
|
|
Open Access:
Green Submitted
|
|
Output Date:
2024-07-01
|
| Record 41 of 44 |
|
Title:
Effect of graphene and bio silica extract from waste coconut shell and rye grass: aluminum silicon alloy hybrid composites for energy storage applications
|
|
Author(s):
Naidu, SCVRM (Naidu, S. C. V. Ramana Murty); Vellingiri, S (Vellingiri, Suresh); Shankar, E (Shankar, E.); Prabhu, P (Prabhu, P.); Srinivasnaik, M (Srinivasnaik, M.); Balamurugan, R (Balamurugan, R.); Raju, VKV (Raju, V. K. Viswanadha) |
| Source:
BIOMASS CONVERSION AND BIOREFINERY DOI:
10.1007/s13399-024-05805-w Early Access Date:
JUN 2024 Published Date:
2024 JUN 8 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
5 |
|
Usage Count
(Since 2013):
5 |
|
Cited Reference Count:
50
|
|
Abstract:
Lightweight and high-strength materials are the significant demand for energy storage applications in recent years. Composite materials have the potential to attain physical, chemical, mechanical, and tribological qualities in the present environment. In this study, graphene (Gr) and biosilica (Bs) nanoparticle extracts from waste coconut shell and rye grass are utilized as reinforcement materials to add to the aluminum silicon (Al-Si) alloy matrix materials. Selective laser melting (SLM) is a rapidly manufacturing technology used to create Al/Gr/Bs hybrid composites. The specimens are made up of four distinct combinations of base matrix alloy (100 wt%), Gr (3, 6, and 9 wt %), and Bs (2, 4, and 6 wt %) with an aluminium alloy matrix. The influence on mechanical characteristics, specifically hardness, tensile strength, and wear, was investigated and compared to the basic matrix alloy. The fracture processes of wear specimens are studied using field emission scanning electron microscopy. Globally, graphene (Gr)-based materials for energy storage devices have been successfully manufactured and deployed in a variety of applications, including super capacitors, lithium-ion batteries, water splitting, fuel cell electrocatalysts, and solar cells. Environmentally friendly graphene (Gr) and biosilica (Bs) nanoparticles have the potential to be used as reinforcement in composite development. These findings showed how promising graphene (Gr) and biosilica (Bs), which are inexpensive reinforcement materials made from leftover coconut shell and rye grass, are for use in energy storage applications. |
|
Accession Number:
WOS:001243290900001
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
Energy Storage; Graphene; Bio silica; SLM; Micro hardness; Tensile strength; Wear |
|
KeyWords Plus:
MECHANICAL-PROPERTIES; MICROSTRUCTURE; WEAR |
Addresses:
[Naidu, S. C. V. Ramana Murty] Sri Venkateswara Coll Engn & Technol, Dept Mech Engn, Srikakulam 532410, Andhra Pradesh, India.
[Vellingiri, Suresh; Prabhu, P.] KIT Kalaignarkarunanidhi Inst Technol, Dept Mech Engn, Coimbatore 641402, Tamil Nadu, India.
[Shankar, E.] Rajalakshmi Engn Coll Rajalakshmi Nagar, Dept Mech Engn, Chennai 602105, Tamil Nadu, India.
[Srinivasnaik, M.] Jawaharlal Nehru Univ JNU, Sch Engn, Dept Mech Engn, New Delhi 110067, India.
[Balamurugan, R.] M Kumarasamy Coll Engn, Dept Mech Engn, Karur 639113, Tamil Nadu, India.
[Raju, V. K. Viswanadha] Sagi Rama Krishnam Raju Engn Coll, Dept Mech Engn, Bhimavaram 534204, Andhra Pradesh, India. |
|
Corresponding Address:
Vellingiri, S (corresponding author), KIT Kalaignarkarunanidhi Inst Technol, Dept Mech Engn, Coimbatore 641402, Tamil Nadu, India. |
|
E-mail Addresses:
scvrmn@gmail.com; winsureshv2011@gmail.com; shankar.e@rajalakshmi.edu.in; prab_er@yahoo.co.in; srinivasmukuloth@gmail.com; balamuruganr.mech@mkce.ac.in; kvraju.vegesna@rediffmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; M.Kumarasamy College of Engineering; SRKR Engineering College |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
|
V K, VISWANADHA RAJU | | 0009-0005-1752-7575 |
|
|
Publisher:
SPRINGER HEIDELBERG
|
|
Publisher Address:
TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Energy & Fuels; Engineering, Chemical |
|
Research Areas:
Energy & Fuels; Engineering |
|
IDS Number:
TS6P5
|
|
ISSN:
2190-6815
|
|
eISSN:
2190-6823
|
|
29-char Source Abbrev.:
BIOMASS CONVERS BIOR
|
|
ISO Source Abbrev.:
Biomass Convers. Biorefinery
|
|
Source Item Page Count:
14
|
|
Output Date:
2024-07-01
|
| Record 42 of 44 |
|
Title:
A Comprehensive Pilot Study to Elucidate the Distinct Gut Microbial Composition and Its Functional Significance in Cardio-Metabolic Disease
|
|
Author(s):
Ray, AK (Ray, Ashwini Kumar); Shukla, A (Shukla, Avaneesh); Yadav, A (Yadav, Alka); Kaur, U (Kaur, Urvinder); Singh, AK (Singh, Alok Kumar); Mago, P (Mago, Payal); Bhavesh, NS (Bhavesh, Neel Sarovar); Chaturvedi, R (Chaturvedi, Rupesh); Tandon, R (Tandon, Ravi); Shalimar (Shalimar); Kumar, A (Kumar, Abhishek); Malik, MZ (Malik, Md. Zubbair) |
| Source:
BIOCHEMICAL GENETICS DOI:
10.1007/s10528-024-10847-w Early Access Date:
JUN 2024 Published Date:
2024 JUN 5 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
115
|
|
Abstract:
Cardio-metabolic disease is a significant global health challenge with increasing prevalence. Recent research underscores the disruption of gut microbial balance as a key factor in disease susceptibility. We aimed to characterize the gut microbiota composition and function in cardio-metabolic disease and healthy controls. For this purpose, we collected stool samples of 18 subjects (12 diseased, 6 healthy) and we performed metagenomics analysis and functional prediction using QIIME2 and PICRUSt. Furthermore, we carried out assessments of microbe-gene interactions, gene ontology, and microbe-disease associations. Our findings revealed distinct microbial patterns in the diseased group, particularly evident in lower taxonomic levels with significant variations in 14 microbial features. The diseased cohort exhibited an enrichment of Lachnospiraceae family, correlating with obesity, insulin resistance, and metabolic disturbances. Conversely, reduced levels of Clostridium, Gemmiger, and Ruminococcus genera indicated a potential inflammatory state, linked to compromised butyrate production and gut permeability. Functional analyses highlighted dysregulated pathways in amino acid metabolism and energy equilibrium, with perturbations correlating with elevated branch-chain amino acid levels-a known contributor to insulin resistance and type 2 diabetes. These findings were consistent across biomarker assessments, microbe-gene associations, and gene ontology analyses, emphasizing the intricate interplay between gut microbial dysbiosis and cardio-metabolic disease progression. In conclusion, our study unveils significant shifts in gut microbial composition and function in cardio-metabolic disease, emphasizing the broader implications of microbial dysregulation. Addressing gut microbial balance emerges as a crucial therapeutic target in managing cardio-metabolic disease burden. |
|
Accession Number:
WOS:001243289000002
|
|
PubMed ID:
38839647
|
|
Language:
English |
|
Document Type:
Article; Early Access |
|
Author Keywords:
Cardio-metabolic disease; Metagenomics; Gut microbes; Inflammation microbes-gene association |
|
KeyWords Plus:
CHAIN AMINO-ACIDS; INTESTINAL MICROBIOTA; INSULIN-RESISTANCE; OBESITY; HEALTHY; GENE; ASSOCIATION; METFORMIN; MARKER; RISK |
Addresses:
[Ray, Ashwini Kumar; Shukla, Avaneesh] Univ Delhi, Dept Environm Studies, New Delhi, India.
[Malik, Md. Zubbair] Dasman Diabet Inst, Dept Genet & Bioinformat, Kuwait, Kuwait.
[Yadav, Alka; Kaur, Urvinder; Chaturvedi, Rupesh; Malik, Md. Zubbair] Jawaharlal Nehru Univ, Sch Biotechnol, New Delhi, India.
[Singh, Alok Kumar] Univ Delhi, Ramjas Coll, Dept Zool, New Delhi, India.
[Mago, Payal] Univ Delhi, Shaheed Rajguru Coll Appl Sci Women, New Delhi, India.
[Mago, Payal] Univ Delhi, Campus Open Learning, New Delhi, India.
[Bhavesh, Neel Sarovar] Int Ctr Genet Engn & Biotechnol, New Delhi, India.
[Tandon, Ravi] Jawaharlal Nehru Univ, Sch Biotechnol, Lab AIDS Res & Immunol, New Delhi, India.
[Shalimar] All India Inst Med Sci, Dept Gastroenterol, New Delhi, India.
[Kumar, Abhishek] Manipal Acad Higher Educ MAHE, Manipal, India.
[Kumar, Abhishek] Int Technol Pk, Inst Bioinformat, Bangalore, India. |
Corresponding Address:
Ray, AK (corresponding author), Univ Delhi, Dept Environm Studies, New Delhi, India.
Malik, MZ (corresponding author), Dasman Diabet Inst, Dept Genet & Bioinformat, Kuwait, Kuwait.
Malik, MZ (corresponding author), Jawaharlal Nehru Univ, Sch Biotechnol, New Delhi, India. |
|
E-mail Addresses:
aray@es.du.ac.in; zubair.bioinfo@gmail.com |
|
Affiliations:
University of Delhi; Dasman Diabetes Institute (DDI); Jawaharlal Nehru University, New Delhi; University of Delhi; University of Delhi; University of Delhi; Department of Biotechnology (DBT) India; International Center for Genetic Engineering & Biotechnology (ICGEB); International Center for Genetic Engineering & Biotechnology (ICGEB), New Delhi; Jawaharlal Nehru University, New Delhi; All India Institute of Medical Sciences (AIIMS) New Delhi; Manipal Academy of Higher Education (MAHE) |
|
Publisher:
SPRINGER/PLENUM PUBLISHERS
|
|
Publisher Address:
233 SPRING ST, NEW YORK, NY 10013 USA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Biochemistry & Molecular Biology; Genetics & Heredity |
|
Research Areas:
Biochemistry & Molecular Biology; Genetics & Heredity |
|
IDS Number:
TS6N6
|
|
ISSN:
0006-2928
|
|
eISSN:
1573-4927
|
|
29-char Source Abbrev.:
BIOCHEM GENET
|
|
ISO Source Abbrev.:
Biochem. Genet.
|
|
Source Item Page Count:
27
|
| Funding: |
| Funding Agency | Grant Number |
|
National Heart, Lung, and Blood Institute (NHLBI) and Fogarty International Centre (FIC), NIH, USA | |
|
National Supercomputing Mission | |
|
Government of India at the Centre For Development of Advanced Computing, Pune | |
|
|
The computational infrastructure and support provided by the “Bioinformatics Research and Application Facility (BRAF)” funded by the National Supercomputing Mission. Government of India at the Centre For Development of Advanced Computing, Pune are gratefully acknowledged.
|
|
Output Date:
2024-07-01
|
| Record 43 of 44 |
|
Title:
Targeting<i> Pf</i>Prohibitin 2-Hu-Hsp70A1A complex as a unique approach towards malaria vaccine development
|
|
Author(s):
Marothia, M (Marothia, Manisha); Behl, A (Behl, Ankita); Maurya, P (Maurya, Preeti); Saini, M (Saini, Monika); Shoaib, R (Shoaib, Rumaisha); Garg, S (Garg, Swati); Kumari, G (Kumari, Geeta); Biswas, S (Biswas, Shreeja); Munjal, A (Munjal, Akshay); Anand, S (Anand, Sakshi); Kahlon, AK (Kahlon, Amandeep Kaur); Gupta, P (Gupta, Pragya); Biswas, S (Biswas, Saurav); Goswami, B (Goswami, Bidhan); Almuqdadi, HTA (Almuqdadi, Haider Thaer Abdulhameed); Bhowmick, IP (Bhowmick, Ipsita Pal); Shevtsov, M (Shevtsov, Maxim); Ramalingam, S (Ramalingam, Sivaprakash); Ranganathan, A (Ranganathan, Anand); Singh, S (Singh, Shailja) |
| Source:
ISCIENCE Volume:
27 Issue:
6 Article Number:
109918 DOI:
10.1016/j.isci.2024.109918 Published Date:
2024 JUN 21 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
1 |
|
Usage Count
(Since 2013):
1 |
|
Cited Reference Count:
49
|
|
Abstract:
Malaria parasite invasion to host erythrocytes is mediated by multiple interactions between merozoite ligands and erythrocyte receptors that contribute toward the development of disease pathology. Here, we report a novel antigen Plasmodium prohibitin “PfPHB2″and identify its cognate partner “Hsp70A1A”in host erythrocyte that plays a crucial role in mediating host -parasite interaction during merozoite invasion. Using small interfering RNA (siRNA)- and glucosamine-6-phosphate riboswitch (glmS) ribozyme-mediated approach, we show that loss of Hsp70A1A in red blood cells (RBCs) or PfPHB2 in infected red blood cells (iRBCs), respectively, inhibit PfPHB2-Hsp70A1A interaction leading to invasion inhibition. Antibodies targeting PfPHB2 and monoclonal antibody therapeutics against Hsp70A1A efficiently block parasite invasion. Recombinant PfPHB2 binds to RBCs which is inhibited by anti-PfPHB2 antibody and monoclonal antibody against Hsp70A1A. The validation of PfPHB2 to serve as antigen is further supported by detection of anti-PfPHB2 antibody in patient sera. Overall, this study proposes PfPHB2 as vaccine candidate and highlights the use of monoclonal antibody therapeutics for future malaria treatment. |
|
Accession Number:
WOS:001244303500001
|
|
PubMed ID:
38812541
|
|
Language:
English |
|
Document Type:
Article |
|
KeyWords Plus:
PLASMODIUM-FALCIPARUM; ERYTHROCYTE INVASION; PROHIBITIN; PROTEIN; ANTIBODIES; CHAPERONES; ANTIGENS; BASIGIN; ROLES |
Addresses:
[Marothia, Manisha; Behl, Ankita; Maurya, Preeti; Saini, Monika; Garg, Swati; Kumari, Geeta; Biswas, Shreeja; Munjal, Akshay; Anand, Sakshi; Kahlon, Amandeep Kaur; Ranganathan, Anand; Singh, Shailja] Jawaharlal Nehru Univ, Special Ctr Mol Med, New Delhi, India.
[Shoaib, Rumaisha; Almuqdadi, Haider Thaer Abdulhameed] Jamia Millia Islamia, Dept Biosci, New Delhi, India.
[Gupta, Pragya; Ramalingam, Sivaprakash] CSIR Inst Genom & Integrat Biol, Mathura Rd, New Delhi 110025, India.
[Biswas, Saurav; Bhowmick, Ipsita Pal] Reg Med Res Ctr Northeast Reg RMRC NE ICMR, Dibrugarh 786001, India.
[Goswami, Bidhan] Agartala Govt Med Coll, Multidisciplinary Res Unit, Agartala, Tripura West, India.
[Almuqdadi, Haider Thaer Abdulhameed] Al Nahrain Univ, Coll Sci, Dept Chem, Baghdad, Iraq.
[Shevtsov, Maxim] Tech Univ Munich, Klinikum Rechts Isar, D-81675 Munich, Germany.
[Shevtsov, Maxim] Russian Acad Sci RAS, Inst Cytol, St Petersburg 194064, Russia.
[Shevtsov, Maxim] Personalized Med Ctr, Almazov Natl Med Res Ctr, Akkuratova Str 2, St Petersburg 197341, Russia. |
|
Corresponding Address:
Ranganathan, A; Singh, S (corresponding author), Jawaharlal Nehru Univ, Special Ctr Mol Med, New Delhi, India. |
|
E-mail Addresses:
anand.icgeb@gmail.com; shailja.jnu@gmail.com |
|
Affiliations:
Jawaharlal Nehru University, New Delhi; Jamia Millia Islamia; Council of Scientific & Industrial Research (CSIR) – India; CSIR – Institute of Genomics & Integrative Biology (IGIB); Al-Nahrain University; Technical University of Munich; Russian Academy of Sciences; St. Petersburg Scientific Centre of the Russian Academy of Sciences; Institute of Cytology RAS; Almazov National Medical Research Centre |
|
Publisher:
CELL PRESS
|
|
Publisher Address:
50 HAMPSHIRE ST, FLOOR 5, CAMBRIDGE, MA 02139 USA
|
|
Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
|
|
Web of Science Categories:
Multidisciplinary Sciences |
|
Research Areas:
Science & Technology – Other Topics |
|
IDS Number:
TW5G3
|
|
eISSN:
2589-0042
|
|
29-char Source Abbrev.:
ISCIENCE
|
|
ISO Source Abbrev.:
iScience
|
|
Source Item Page Count:
23
|
| Funding: |
| Funding Agency | Grant Number |
|
DBT-Research Associateship |
DBT-RA/2023/January/N/3456
|
|
SNU-Foundation fellowship | |
|
Intensification of Research in High Priority Areas (IRHPA) of Science and Engineering Research Board (SERB) |
IRHPA IPA/2020/000007
|
|
Indian Council of Medical Research |
NER/84/2022-ECD-I
|
|
DBT | |
|
Ministry of Science and Higher Education of the Russian Federation |
075-15-2022-301
|
|
|
M.M. is ICMR-SRF, and A.B. is supported by DBT-Research Associateship (DBT-RA/2023/January/N/3456) . P.M. is DBT-JRF, and M.S. is supported by SNU-Foundation fellowship. This work is supported by funding from Intensification of Research in High Priority Areas (IRHPA) of Science and Engineering Research Board (SERB; IRHPA IPA/2020/000007) (A.R., S.S.) . Grant from Indian Council of Medical Research (NER/84/2022-ECD-I) and the National Bioscience Award from DBT for S.S. is acknowledged. M. Shevtsov was financially supported by the Ministry of Science and Higher Education of the Russian Federation (agreement no. 075-15-2022-301) . HA-glmS plasmid was a kind gift from Prof. Paul Gilson, Co -group Head, Malaria Virulence and Drug Discovery Group; Head of Burnet Cell Imaging Facility, Burnet Institute. Model in Figure 8 was designed using BioRender (BioRender.com ) .
|
|
Open Access:
gold
|
|
Output Date:
2024-07-01
|
| Record 44 of 44 |
|
Title:
Optimal rainfall threshold for monsoon rice production in India varies across space and time
|
|
Author(s):
Maiti, A (Maiti, Arabinda); Hasan, MK (Hasan, Md Kamrul); Sannigrahi, S (Sannigrahi, Srikanta); Bar, S (Bar, Somnath); Chakraborti, S (Chakraborti, Suman); Mahto, SS (Mahto, Shanti Shwarup); Chatterjee, S (Chatterjee, Sumanta); Pramanik, S (Pramanik, Suvamoy); Pilla, F (Pilla, Francesco); Auerbach, J (Auerbach, Jeremy); Sonnentag, O (Sonnentag, Oliver); Song, CH (Song, Conghe); Zhang, Q (Zhang, Qi) |
| Source:
COMMUNICATIONS EARTH & ENVIRONMENT Volume:
5 Issue:
1 Article Number:
302 DOI:
10.1038/s43247-024-01414-7 Published Date:
2024 JUN 6 |
|
Times Cited in Web of Science Core Collection:
0
|
|
Total Times Cited:
0
|
|
Usage Count
(Last 180 days):
0 |
|
Usage Count
(Since 2013):
0 |
|
Cited Reference Count:
54
|
Abstract:
Climate change affects Indian agriculture, which depends heavily on the spatiotemporal distribution of monsoon rainfall. Despite the nonlinear relationship between crop yield and rainfall, little is known about the optimal rainfall threshold, particularly for monsoon rice. Here, we investigate the responses of rice yield to monsoon rainfall in India by analyzing historical rice production statistics and climate data from 1990 to 2017. Results show that excessive and deficit rainfall reduces rice yield by 33.7% and 19%, respectively. The overall optimal rainfall threshold nationwide is 1621 +/- 34 mm beyond which rice yield declines by 6.4 kg per hectare per 100 mm of rainfall, while the identifiable thresholds vary spatially across 14 states. The temporal variations in rice yield are influenced by rainfall anomalies featured by El Ni & ntilde;o-Southern Oscillation events.
Excessive rainfalls have led to a greater decrease in monsoon-season rice yield in India than deficit rainfalls, suggests a statistical analysis of historical rice production and climate data from 1990 to 2017. |
|
Accession Number:
WOS:001244003700001
|
|
Language:
English |
|
Document Type:
Article |
|
KeyWords Plus:
CLIMATE-CHANGE; SEGMENTED REGRESSION; CROP YIELD; IMPACT; TRENDS; ENSO |
Addresses:
[Maiti, Arabinda] Vidyasagar Univ, Dept Geog, Midnapore 721102, W Bengal, India.
[Hasan, Md Kamrul] Patuakhali Sci & Technol Univ, Dept Agr Extens & Rural Dev, Dumki 8602, Patuakhali, Bangladesh.
[Sannigrahi, Srikanta; Auerbach, Jeremy] Univ Coll Dublin, Sch Geog, Newman Bldg, Dublin, Ireland.
[Bar, Somnath] Univ Southampton, Sch Geog & Environm Sci, Southampton SO171BJ, England.
[Chakraborti, Suman; Pramanik, Suvamoy] Jawaharlal Nehru Univ, Ctr Study Reg Dev, Delhi 110067, India.
[Mahto, Shanti Shwarup] Indian Inst Technol IIT, Earth Sci, Gandhinagar, India.
[Chatterjee, Sumanta] ARS, USDA, Hydrol & Remote Sensing Lab, 10300 Baltimore Ave, Beltsville, MD 20705 USA.
[Chatterjee, Sumanta] ICAR Natl Rice Res Inst, Cuttack 753006, India.
[Pilla, Francesco] Univ Coll Dublin, Sch Architecture Planning & Environm Policy, Dublin D04 V1W8, Ireland.
[Sonnentag, Oliver] Univ Montreal, Dept Geog, Montreal, PQ, Canada.
[Sonnentag, Oliver] Univ Montreal, Ctr Etud Nord, Montreal, PQ, Canada.
[Song, Conghe; Zhang, Qi] Univ N Carolina, Dept Geog & Environm, Chapel Hill, NC 27599 USA. |
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Corresponding Address:
Zhang, Q (corresponding author), Univ N Carolina, Dept Geog & Environm, Chapel Hill, NC 27599 USA. |
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E-mail Addresses:
qz@unc.edu |
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Affiliations:
Vidyasagar University; University College Dublin; University of Southampton; Jawaharlal Nehru University, New Delhi; Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) – Madras; United States Department of Agriculture (USDA); Indian Council of Agricultural Research (ICAR); ICAR – National Rice Research Institute; University College Dublin; Universite de Montreal; Universite de Montreal; University of North Carolina; University of North Carolina Chapel Hill |
| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
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Auerbach, Jeremy | HJP-9177-2023 | 0000-0003-0061-7943 |
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Pilla, Francesco | | 0000-0002-1535-1239 |
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MAHTO, SHANTI SHWARUP | | 0000-0003-3224-4969 |
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Publisher:
SPRINGERNATURE
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Publisher Address:
CAMPUS, 4 CRINAN ST, LONDON, N1 9XW, ENGLAND
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Web of Science Index:
Science Citation Index Expanded (SCI-EXPANDED)
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Web of Science Categories:
Environmental Sciences; Geosciences, Multidisciplinary; Meteorology & Atmospheric Sciences |
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Research Areas:
Environmental Sciences & Ecology; Geology; Meteorology & Atmospheric Sciences |
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IDS Number:
TV3U6
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eISSN:
2662-4435
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29-char Source Abbrev.:
COMMUN EARTH ENVIRON
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ISO Source Abbrev.:
Commun. Earth Environ.
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Source Item Page Count:
8
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| Funding: |
| Funding Agency | Grant Number |
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National Science Foundation (NSF) |
2108238
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U.S. National Science Foundation DISES Program | |
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This research was supported by the U.S. National Science Foundation DISES Program (2108238).
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Open Access:
gold
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Output Date:
2024-07-01
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| Record 15 of 21 |
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Title:
OsRR26, a type-B response regulator, modulates salinity tolerance in rice via phytohormone-mediated ROS accumulation in roots and influencing reproductive development
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Author(s):
Nongpiur, RC (Nongpiur, Ramsong Chantre); Rawat, N (Rawat, Nishtha); Singla-Pareek, SL (Singla-Pareek, Sneh Lata); Pareek, A (Pareek, Ashwani) |
| Source:
PLANTA Volume:
259 Issue:
5 Article Number:
96 DOI:
10.1007/s00425-024-04366-6 Published Date:
2024 MAY |
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Abstract:
Main ConclusionOsRR26 is a cytokinin-responsive response regulator that promotes phytohormone-mediated ROS accumulation in rice roots, regulates seedling growth, spikelet fertility, awn development, represses NADPH oxidases, and negatively affects salinity tolerance.Plant two-component systems (TCS) play a pivotal role in phytohormone signaling, stress responses, and circadian rhythm. However, a significant knowledge gap exists regarding TCS in rice. In this study, we utilized a functional genomics approach to elucidate the role of OsRR26, a type-B response regulator in rice. Our results demonstrate that OsRR26 is responsive to cytokinin, ABA, and salinity stress, serving as the ortholog of Arabidopsis ARR11. OsRR26 primarily localizes to the nucleus and plays a crucial role in seedling growth, spikelet fertility, and the suppression of awn development. Exogenous application of cytokinin led to distinct patterns of reactive oxygen species (ROS) accumulation in the roots of both WT and transgenic plants (OsRR26OE and OsRR26KD), indicating the potential involvement of OsRR26 in cytokinin-mediated ROS signaling in roots. The application of exogenous ABA resulted in varied cellular compartmentalization of ROS between the WT and transgenic lines. Stress tolerance assays of these plants revealed that OsRR26 functions as a negative regulator of salinity stress tolerance across different developmental stages in rice. Physiological and biochemical analyses unveiled that the knockdown of OsRR26 enhances salinity tolerance, characterized by improved chlorophyll retention and the accumulation of soluble sugars, K+ content, and amino acids, particularly proline.Main ConclusionOsRR26 is a cytokinin-responsive response regulator that promotes phytohormone-mediated ROS accumulation in rice roots, regulates seedling growth, spikelet fertility, awn development, represses NADPH oxidases, and negatively affects salinity tolerance.Plant two-component systems (TCS) play a pivotal role in phytohormone signaling, stress responses, and circadian rhythm. However, a significant knowledge gap exists regarding TCS in rice. In this study, we utilized a functional genomics approach to elucidate the role of OsRR26, a type-B response regulator in rice. Our results demonstrate that OsRR26 is responsive to cytokinin, ABA, and salinity stress, serving as the ortholog of Arabidopsis ARR11. OsRR26 primarily localizes to the nucleus and plays a crucial role in seedling growth, spikelet fertility, and the suppression of awn development. Exogenous application of cytokinin led to distinct patterns of reactive oxygen species (ROS) accumulation in the roots of both WT and transgenic plants (OsRR26OE and OsRR26KD), indicating the potential involvement of OsRR26 in cytokinin-mediated ROS signaling in roots. The application of exogenous ABA resulted in varied cellular compartmentalization of ROS between the WT and transgenic lines. Stress tolerance assays of these plants revealed that OsRR26 functions as a negative regulator of salinity stress tolerance across different developmental stages in rice. Physiological and biochemical analyses unveiled that the knockdown of OsRR26 enhances salinity tolerance, characterized by improved chlorophyll retention and the accumulation of soluble sugars, K+ content, and amino acids, particularly proline. |
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Accession Number:
WOS:001189228400001
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PubMed ID:
38517516
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| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
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Pareek, Ashwani | | 0000-0002-2923-0681 |
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ISSN:
0032-0935
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eISSN:
1432-2048
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| Record 5 of 40 |
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Title:
Graphic, Quantitation, Visualization, Standardization, Digitization, and Intelligence of Electrolyte and Electrolyte-Electrode Interface
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Author(s):
Cai, T (Cai, Tao); Wang, YQ (Wang, Yuqi); Zhao, F (Zhao, Fei); Ma, Z (Ma, Zheng); Kumar, P (Kumar, Pushpendra); Xie, HL (Xie, Hongliang); Sun, CS (Sun, Chunsheng); Wang, J (Wang, Jing); Li, Q (Li, Qian); Guo, YJ (Guo, Yingjun); Ming, J (Ming, Jun) |
| Source:
ADVANCED ENERGY MATERIALS DOI:
10.1002/aenm.202400569 Early Access Date:
APR 2024 Published Date:
2024 APR 22 |
Abstract:
Electrolytes have recently regained significant attention in rechargeable batteries due to the discovery that the electrolyte microstructures play a determinant role in battery performance. By adjusting the compositions of electrolytes to cater to various functionalities, such as high-voltage, fast-charging, wide-temperature operation, and non-flammable features, a diverse range of batteries can be developed to adapt to different environmental working conditions. Nevertheless, elucidating the electrolyte microstructures and understanding the associated electrode interfacial behaviors remain challenging. These challenges arise from the interdisciplinary nature of the research, encompassing subjects such as solution chemistry, interface chemistry, electrochemistry, and organic chemistry. This topic holds particular significance because solution chemistry and solution-solid interface chemistry are ubiquitous in daily lives, yet their behaviors remain unclear due to their inherent complexity, dynamic nature, and rapid variability. In this context, electrolyte and electrolyte-electrode interface research are used as an illustrative example and summarize their progress from six key perspectives of graphic, quantitation, visualization, standardization, digitization, and intelligence. It is aimed to provide a multi-faceted understanding of electrolyte microstructures and their behaviors on the electrode interface. This comprehensive approach enables the effective design of electrolytes and enhances the accuracy of predicting battery performance, servicing the development of solution and solution-solid interface.
A comprehensive review of the electrolyte and electrolyte-electrode interface research is summarized from six aspects of graphic, quantitation, visualization, standardization, digitization, and intelligence. This review aimed to have multiple view-angles to understand electrolyte microstructures and their behaviors on electrode interface, in turn designing electrolytes and predicting battery performance effectively, and also servicing the development of the solution and solution-solid interface. image |
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Accession Number:
WOS:001206555700001
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| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
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Ming, Jun | B-5193-2016 | 0000-0001-9561-5718 |
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ISSN:
1614-6832
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eISSN:
1614-6840
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| Record 12 of 40 |
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Title:
Small molecules that disrupt RAD54-BLM interaction hamper tumor proliferation in colon cancer chemoresistance models
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Author(s):
Kaur, E (Kaur, Ekjot); Agrawal, R (Agrawal, Ritu); Arun, R (Arun, Rimpy); Madhavan, V (Madhavan, Vinoth); Srivastava, V (Srivastava, Vivek); Kumar, D (Kumar, Dilip); Rath, PP (Rath, Pragyan Parimita); Kumar, N (Kumar, Nitin); Vedagopuram, S (Vedagopuram, Sreekanth); Pandey, N (Pandey, Nishant); Priya, S (Priya, Swati); Legembre, P (Legembre, Patrick); Gourinath, S (Gourinath, Samudrala); Bajaj, A (Bajaj, Avinash); Sengupta, S (Sengupta, Sagar) |
| Source:
JOURNAL OF CLINICAL INVESTIGATION Volume:
134 Issue:
8 Article Number:
e161941 DOI:
10.1172/JCI161941 Published Date:
2024 APR 15 |
|
Abstract:
RAD54 and BLM helicase play pivotal roles during homologous recombination repair (HRR) to ensure genome maintenance. BLM amino acids (aa 181-212) interact with RAD54 and enhance its chromatin remodeling activity. Functionally, this interaction heightens HRR, leading to a decrease in residual DNA damage in colon cancer cells. This contributes to chemoresistance in colon cancer cells against cisplatin, camptothecin, and oxaliplatin, eventually promoting tumorigenesis in preclinical colon cancer mouse models. ChIP-Seq analysis and validation revealed increased BLM and RAD54 corecruitment on the MRP2 promoter in camptothecin-resistant colon cancer cells, leading to BLM-dependent enhancement of RAD54mediated chromatin remodeling. We screened the Prestwick small -molecule library, with the intent to revert camptothecinand oxaliplatin-induced chemoresistance by disrupting the RAD54-BLM interaction. Three FDA/European Medicines Agency-approved candidates were identified that could disrupt this interaction. These drugs bound to RAD54, altered its conformation, and abrogated RAD54-BLM-dependent chromatin remodeling on G5E4 and MRP2 arrays. Notably, the small molecules also reduced HRR efficiency in resistant lines, diminished anchorage -independent growth, and hampered the proliferation of tumors generated using camptothecinand oxaliplatin-resistant colon cancer cells in both xenograft and syngeneic mouse models in BLM-dependent manner. Therefore, the 3 identified small molecules can serve as possible viable candidates for adjunct therapy in colon cancer treatment. |
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Accession Number:
WOS:001208946600010
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|
PubMed ID:
38421735
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| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
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KUMAR, DILIP | GXH-1843-2022 | 0000-0002-1848-3034 |
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Vedagopuram, Sreekanth | G-6493-2017 | 0000-0002-7065-2675 |
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RATH, PRAGYAN PARIMITA | | 0000-0002-1207-9735 |
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Sengupta, Sagar | | 0000-0002-6365-1770 |
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ISSN:
0021-9738
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eISSN:
1558-8238
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| Record 18 of 40 |
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Title:
Quest for a Desolvated Structure Unveils Breathing Phenomena in a MOF Leading to Greener Catalysis in a Solventless Setup: Insights from Combined Experimental and Computational Studies
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Author(s):
Kumari, S (Kumari, Sarita); Yadav, A (Yadav, Anand); Kumari, A (Kumari, Ankita); Mahapatra, S (Mahapatra, Somanath); Kumar, D (Kumar, Devender); Sharma, J (Sharma, Jyoti); Yadav, P (Yadav, Preety); Ghosh, D (Ghosh, Dibyajyoti); Chakraborty, A (Chakraborty, Anindita); Kanoo, P (Kanoo, Prakash) |
| Source:
INORGANIC CHEMISTRY Volume:
63 Issue:
16 Pages:
7146-7160 DOI:
10.1021/acs.inorgchem.3c04062 Early Access Date:
APR 2024 Published Date:
2024 APR 9 |
|
Abstract:
The crystal structure of the metal-organic framework (MOF), {Mn-2(1,4-bdc)(2)(DMF)(2)}(n) (1) (1,4-bdcH(2), 1,4-benzenedicarboxylic acid; DMF, N,N-dimethylformamide), is known for a long time; however, its desolvated structure, {Mn-2(1,4-bdc)(2)}(n) (1 ‘), is not yet known. The first-principles-based computational simulation was used to unveil the structure of 1 ‘ that shows the expansion in the framework, leading to pore opening after the removal of coordinated DMF molecules. We have used 1 ‘ that contains open metal sites (OMSs) in the structure in cyanosilylation and CO2 cycloaddition reactions and recorded complete conversions in a solventless setup. The pore opening in 1 ‘ allows the facile diffusion of small aldehyde molecules into the channels, leading to complete conversion. The reactions with larger aldehydes, 2-naphthaldehyde and 9-anthracenecarboxaldehyde, also show 99.9% conversions, which are the highest reported until date in solventless conditions. The in silico simulations illustrate that larger aldehydes interact with Mn(II) OMSs on the surfaces, enabling a closer interaction and facilitating complete conversions. The catalyst shows high recyclability, exhibiting 99.9% conversions in the successive reaction cycles with negligible change in the structure. Our investigations illustrate that the catalyst 1 ‘ is economical, efficient, and robust and allows reactions in a solventless greener setup, and therefore the catalysis with 1 ‘ can be regarded as “green catalysis”. |
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Accession Number:
WOS:001199621300001
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PubMed ID:
38592926
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ISSN:
0020-1669
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eISSN:
1520-510X
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| Record 20 of 40 |
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Title:
Dynamics and drivers of mycorrhizal fungi after glacier retreat
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Author(s):
Carteron, A (Carteron, Alexis); Cantera, I (Cantera, Isabel); Guerrieri, A (Guerrieri, Alessia); Marta, S (Marta, Silvio); Bonin, A (Bonin, Aurelie); Ambrosini, R (Ambrosini, Roberto); Anthelme, F (Anthelme, Fabien); Azzoni, RS (Azzoni, Roberto Sergio); Almond, P (Almond, Peter); Gazitúa, PA (Alviz Gazitua, Pablo); Cauvy-Fraunie, S (Cauvy-Fraunie, Sophie); Lievano, JLC (Ceballos Lievano, Jorge Luis); Chand, P (Chand, Pritam); Sharma, MC (Chand Sharma, Milap); Clague, JJ (Clague, John J.); Rapre, JAC (Cochachin Rapre, Justiniano Alejo); Compostella, C (Compostella, Chiara); Encarnacion, RC (Cruz Encarnacion, Rolando); Dangles, O (Dangles, Olivier); Eger, A (Eger, Andre); Erokhin, S (Erokhin, Sergey); Franzetti, A (Franzetti, Andrea); Gielly, L (Gielly, Ludovic); Gili, F (Gili, Fabrizio); Gobbi, M (Gobbi, Mauro); Hagvar, S (Hagvar, Sigmund); Khedim, N (Khedim, Norine); Meneses, RI (Meneses, Rosa Isela); Peyre, G (Peyre, Gwendolyn); Pittino, F (Pittino, Francesca); Rabatel, A (Rabatel, Antoine); Urseitova, N (Urseitova, Nurai); Yang, Y (Yang, Yan); Zaginaev, V (Zaginaev, Vitalii); Zerboni, A (Zerboni, Andrea); Zimmer, A (Zimmer, Anais); Taberlet, P (Taberlet, Pierre); Diolaiuti, GA (Diolaiuti, Guglielmina Adele); Poulenard, J (Poulenard, Jerome); Thuiller, W (Thuiller, Wilfried); Caccianiga, M (Caccianiga, Marco); Ficetola, GF (Ficetola, Gentile Francesco) |
| Source:
NEW PHYTOLOGIST Volume:
242 Issue:
4 Pages:
1739-1752 DOI:
10.1111/nph.19682 Early Access Date:
APR 2024 Published Date:
2024 MAY |
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Abstract:
The development of terrestrial ecosystems depends greatly on plant mutualists such as mycorrhizal fungi. The global retreat of glaciers exposes nutrient-poor substrates in extreme environments and provides a unique opportunity to study early successions of mycorrhizal fungi by assessing their dynamics and drivers. We combined environmental DNA metabarcoding and measurements of local conditions to assess the succession of mycorrhizal communities during soil development in 46 glacier forelands around the globe, testing whether dynamics and drivers differ between mycorrhizal types. Mycorrhizal fungi colonized deglaciated areas very quickly (< 10 yr), with arbuscular mycorrhizal fungi tending to become more diverse through time compared to ectomycorrhizal fungi. Both alpha- and beta-diversity of arbuscular mycorrhizal fungi were significantly related to time since glacier retreat and plant communities, while microclimate and primary productivity were more important for ectomycorrhizal fungi. The richness and composition of mycorrhizal communities were also significantly explained by soil chemistry, highlighting the importance of microhabitat for community dynamics. The acceleration of ice melt and the modifications of microclimate forecasted by climate change scenarios are expected to impact the diversity of mycorrhizal partners. These changes could alter the interactions underlying biotic colonization and belowground-aboveground linkages, with multifaceted impacts on soil development and associated ecological processes. |
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Accession Number:
WOS:001197763400001
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PubMed ID:
38581206
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| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
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Guerrieri, Alessia | | 0000-0002-1519-3517 |
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Anthelme, Fabien | | 0000-0001-6249-995X |
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Marta, Silvio | | 0000-0001-8850-610X |
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Gili, Fabrizio | | 0000-0002-1817-0193 |
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Azzoni, Roberto Sergio | | 0000-0002-5931-486X |
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Carteron, Alexis | | 0000-0003-4162-9254 |
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Bonin, Aurelie | | 0000-0001-7800-8609 |
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ISSN:
0028-646X
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eISSN:
1469-8137
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| Record 28 of 40 |
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Title:
Isolation, Characterization, and Expression Analysis of NAC Transcription Factor from <i>Andrographis paniculata</i> (Burm. f.) Nees and Their Role in Andrographolide Production
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Author(s):
Kumar, R (Kumar, Ramesh); Kumar, C (Kumar, Chavlesh); Choudhury, DR (Choudhury, Debjani Roy); Ranjan, A (Ranjan, Aashish); Raipuria, RK (Raipuria, Ritesh Kumar); Dubey, KKD (Dubey, Kaushik Kumar Dhar); Mishra, A (Mishra, Ayushi); Kumar, C (Kumar, Chetan); Manzoor, MM (Manzoor, Malik Muzafar); Kumar, A (Kumar, Ashok); Kumari, A (Kumari, Abha); Singh, K (Singh, Kuldeep); Singh, GP (Singh, Gyanendra Pratap); Singh, R (Singh, Rakesh) |
| Source:
GENES Volume:
15 Issue:
4 Article Number:
422 DOI:
10.3390/genes15040422 Published Date:
2024 APR |
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Abstract:
Andrographis paniculata (Burm. f.) Nees is an important medicinal plant known for its bioactive compound andrographolide. NAC transcription factors (NAM, ATAF1/2, and CUC2) play a crucial role in secondary metabolite production, stress responses, and plant development through hormonal signaling. In this study, a putative partial transcript of three NAC family genes (ApNAC83, ApNAC21 22 and ApNAC02) was used to isolate full length genes using RACE. Bioinformatics analyses such as protein structure prediction, cis-acting regulatory elements, and gene ontology analysis were performed. Based on in silico predictions, the diterpenoid profiling of the plant’s leaves (five-week-old) and the real-time PCR-based expression analysis of isolated NAC genes under abscisic acid (ABA) treatment were performed. Additionally, the expression analysis of isolated NAC genes under MeJA treatment and transient expression in Nicotiana tabacum was performed. Full-length sequences of three members of the NAC transcription factor family, ApNAC83 (1102 bp), ApNAC21 22 (996 bp), and ApNAC02 (1011 bp), were isolated and subjected to the promoter and gene ontology analysis, which indicated their role in transcriptional regulation, DNA binding, ABA-activated signaling, and stress management. It was observed that ABA treatment leads to a higher accumulation of andrographolide and 14-deoxyandrographolide content, along with the upregulation of ApNAC02 (9.6-fold) and the downregulation of ApNAC83 and ApNAC21 22 in the leaves. With methyl jasmonate treatment, ApNAC21 22 expression decreased, while ApNAC02 increased (1.9-fold), with no significant change being observed in ApNAC83. The transient expression of the isolated NAC genes in a heterologous system (Nicotiana benthamiana) demonstrated their functional transcriptional activity, leading to the upregulation of the NtHMGR gene, which is related to the terpene pathway in tobacco. The expression analysis and heterologous expression of ApNAC21 22 and ApNAC02 indicated their role in andrographolide biosynthesis. |
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Accession Number:
WOS:001211059000001
|
|
PubMed ID:
38674357
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| Author Identifiers: |
| Author | Web of Science ResearcherID | ORCID Number |
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Manzoor, Malik Muzafar | | 0000-0001-8906-1106 |
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eISSN:
2073-4425
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| Record 30 of 40 |
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Title:
Herbo-Mineral Medicine, Lithom Exhibits Anti-Nephrolithiasis Activity in Rat Model of Hyperoxaluria by Attenuating Calcium Oxalate Crystal Formation and Oxidative Stress
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Author(s):
Balkrishna, A (Balkrishna, Acharya); Sinha, S (Sinha, Sandeep); Manik, M (Manik, Moumita); Pandey, A (Pandey, Anupam); Maity, M (Maity, Madhulina); Dev, R (Dev, Rishabh); Varshney, A (Varshney, Anurag) |
| Source:
DISCOVERY MEDICINE Volume:
36 Issue:
183 Pages:
799-815 DOI:
10.24976/Discov.Med.202436183.75 Published Date:
2024 APR |
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Abstract:
Background: Calcium oxalate monohydrate (COM) forms the most common type of kidney stones observed in clinics, elevated levels of urinary oxalate being the principal risk factor for such an etiology. The objective of the present study was to evaluate the anti-nephrolithiatic effect of herbo-mineral formulation, Lithom. Methods: The in vitro biochemical synthesis of COM crystals in the presence of Lithom was performed and observations were made by microscopy and Scanning Electron Microscope (SEM) based analysis for the detection of crystal size and morphology. The phytochemical composition of Lithom was evaluated by Ultra-High-Performance Liquid Chromatography (UHPLC). The in vivo model of Ethylene glycol-induced hyperoxaluria in Sprague-Dawley rats was used for the evaluation of Lithom. The animals were randomly allocated to 5 different groups namely Normal control, Disease control (ethylene glycol (EG), 0.75%, 28 days), Allopurinol (50 mg/kg, q.d.), Lithom (43 mg/kg, b.i.d.), and Lithom (129 mg/kg, b.i.d.). Analysis of crystalluria, oxalate, and citrate levels, oxidative stress parameters (malondialdehyde (MDA), catalase, myeloperoxidase (MPO)), and histopathology by hematoxylin and eosin (H&E) and Von Kossa staining was performed for evaluation of Lithom. Results: The presence of Lithom during COM crystals synthesis significantly reduced the average crystal area, feret’s diameter, and area-perimeter ratio, in a dose-dependent manner. SEM analysis revealed that COM crystals synthesized in the presence of 100 and 300 mu g/mL of Lithom exhibited a veritable morphological transition from irregular polygons with sharp edges to smoothened smaller cuboid polygons. UHPLC analysis of Lithom revealed the presence of Trigonelline, Bergenin, Xanthosine, Adenosine, Bohoervinone B, Vanillic acid, and Ellagic acid as key phytoconstituents. In EG-induced SD rats, the Lithom-treated group showed a decrease in elevated urinary oxalate levels, oxidative stress, and renal inflammation. Von Kossa staining of kidney tissue also exhibited a marked reduction in crystal depositions in Lithom-treated groups. Conclusion: Taken together, Lithom could be a potential clinical-therapeutic alternative for management of nephrolithiasis. |
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Accession Number:
WOS:001209121600009
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PubMed ID:
38665028
|
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ISSN:
1539-6509
|
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eISSN:
1944-7930
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